CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjogren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells. | CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells. Hinrichs AC, Kruize AA, Lafeber FPJG, Leavis HL, van Roon JAG., Free PMC Article | 08/19/2023 |
LncRNA15691 promotes T-ALL infiltration by upregulating CCR9 via increased MATR3 stability. | LncRNA15691 promotes T-ALL infiltration by upregulating CCR9 via increased MATR3 stability. Zeng X, Lei Y, Pan S, Sun J, He H, Xiao D, Jamal M, Shen H, Zhou F, Shao L, Zhang Q. | 02/27/2023 |
In patients with primary Sjogren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-gamma, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells. | In patients with primary Sjögren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells. Hinrichs AC, Kruize AA, Leavis HL, van Roon JAG., Free PMC Article | 01/11/2023 |
CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjogren's Syndrome. | CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren's Syndrome. Hinrichs AC, Blokland SLM, Kruize AA, Lafeber FPJ, Leavis HL, van Roon JAG., Free PMC Article | 07/2/2022 |
Potential for CCR9+ IL-17+ Regulatory T Cell as a Predictor of Early Necrotizing Enterocolitis. | Potential for CCR9+ IL-17+ Regulatory T Cell as a Predictor of Early Necrotizing Enterocolitis. Li F, Hao H, Gao X, Cai Y, Zhou J, Wang D, Xiao X, Li S, Ma F. | 05/21/2022 |
Role of CC chemokine receptor 9 in the progression of murine and human non-alcoholic steatohepatitis. | Role of CC chemokine receptor 9 in the progression of murine and human non-alcoholic steatohepatitis. Morikawa R, Nakamoto N, Amiya T, Chu PS, Koda Y, Teratani T, Suzuki T, Kurebayashi Y, Ueno A, Taniki N, Miyamoto K, Yamaguchi A, Shiba S, Katayama T, Yoshida K, Takada Y, Ishihara R, Ebinuma H, Sakamoto M, Kanai T. | 01/22/2022 |
Development of Anti-Human CC Chemokine Receptor 9 Monoclonal Antibodies for Flow Cytometry. | Development of Anti-Human CC Chemokine Receptor 9 Monoclonal Antibodies for Flow Cytometry. Nanamiya R, Takei J, Asano T, Tanaka T, Sano M, Nakamura T, Yanaka M, Hosono H, Kaneko MK, Kato Y. | 01/8/2022 |
LINC00853 restrains T cell acute lymphoblastic leukemia invasion and infiltration by regulating CCR9/CCL25. | LINC00853 restrains T cell acute lymphoblastic leukemia invasion and infiltration by regulating CCR9/CCL25. Li J, Muhammad J, Xie T, Sun J, Lei Y, Wei Z, Pan S, Qin H, Shao L, Jiang D, Zhang Q. | 12/25/2021 |
CCL25 and CCR9 is a unique pathway that potentiates pannus formation by remodeling RA macrophages into mature osteoclasts. | CCL25 and CCR9 is a unique pathway that potentiates pannus formation by remodeling RA macrophages into mature osteoclasts. Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Ahmad I, Tetali C, Sweiss N, Amin MA, Zomorrodi RK, Shahrara S., Free PMC Article | 09/25/2021 |
The Regulatory Function of CCR9(+) Dendritic Cells in Inflammation and Autoimmunity. | The Regulatory Function of CCR9(+) Dendritic Cells in Inflammation and Autoimmunity. Pathak M, Lal G., Free PMC Article | 05/1/2021 |
Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19. | Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19. Yao Y, Ye F, Li K, Xu P, Tan W, Feng Q, Rao S., Free PMC Article | 03/13/2021 |
CCR9 Promotes Migration and Invasion of Lung Adenocarcinoma Cancer Stem Cells. | CCR9 Promotes Migration and Invasion of Lung Adenocarcinoma Cancer Stem Cells. Lu L, Du H, Huang H, Wang C, Wang P, Zha Z, Wu Y, Liu X, Weng C, Fang X, Li B, Mao H, Wang L, Guan M, Liu G., Free PMC Article | 02/27/2021 |
The role of the CCL25-CCR9 axis in beta-cell function: potential for therapeutic intervention in type 2 diabetes. | The role of the CCL25-CCR9 axis in beta-cell function: potential for therapeutic intervention in type 2 diabetes. Atanes P, Lee V, Huang GC, Persaud SJ. | 12/26/2020 |
Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9(+) T cells. | Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9(+) T cells. Chen H, Cong X, Wu C, Wu X, Wang J, Mao K, Li J, Zhu G, Liu F, Meng X, Song J, Sun X, Wang X, Liu S, Zhang S, Yang X, Song Y, Yang YG, Sun T., Free PMC Article | 11/21/2020 |
Study provides evidence that high expression levels of CCR5, CCR6 and CCR9 are associated with prolonged overall survival in patients with earlystage pancreatic ductal adenocarcinoma (PDAC). Collectively, this highlights that CCR5, CCR6 and CCR9 are potential prognostic biomarkers for earlystage PDAC. | Clinical significance and prospective molecular mechanism of C‑C motif chemokine receptors in patients with early‑stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy. Zhou X, Liao X, Wang X, Huang K, Yang C, Yu T, Liu J, Han C, Zhu G, Su H, Qin W, Han Q, Liu Z, Huang J, Gong Y, Ye X, Peng T., Free PMC Article | 02/29/2020 |
our observations of increased circulating CCR9+ IL-17+ Treg cells and its inverse correlation with the severity of intestinal tissue injury in NEC are novel | Interleukin-6-mediated CCR9(+) interleukin-17-producing regulatory T cells polarization increases the severity of necrotizing enterocolitis. Ma F, Li S, Gao X, Zhou J, Zhu X, Wang D, Cai Y, Li F, Yang Q, Gu X, Ge W, Liu H, Xiao X, Hao H., Free PMC Article | 12/21/2019 |
There were significantly increased CCR9 protein levels in failing human hearts. | C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. Xu Z, Mei F, Liu H, Sun C, Zheng Z., Free PMC Article | 01/6/2018 |
this study showed that CCR7 are overexpressed in CD4(-) CD8(-) thymocytes of myasthenia gravis patients. | CCR9 AND CCR7 are overexpressed in CD4(-) CD8(-) thymocytes of myasthenia gravis patients. Li Q, Liu P, Xuan X, Zhang J, Zhang Y, Zhu Z, Gao F, Zhang Q, Du Y. | 07/8/2017 |
Results indicated that the expression levels of CCR9 in lesional skin may be a useful biologic marker of the clinical efficacy of infliximab therapy in psoriasis patients. | Enhanced CCR9 expression levels in psoriatic skin are associated with poor clinical outcome to infliximab treatment. Koga A, Kajihara I, Yamada S, Makino K, Ichihara A, Aoi J, Makino T, Fukushima S, Jinnin M, Ihn H. | 05/20/2017 |
Xray crystal structure of the CCR9 receptor in complex with vercirnon at 2.8 A resolution | Intracellular allosteric antagonism of the CCR9 receptor. Oswald C, Rappas M, Kean J, Doré AS, Errey JC, Bennett K, Deflorian F, Christopher JA, Jazayeri A, Mason JS, Congreve M, Cooke RM, Marshall FH. | 04/8/2017 |
It plays a pathogenic role in liver diseases and it will be a therapeutic target of the diseases. | [Role of inflammatory macrophages and CCR9/CCL25 chemokine axis in the pathogenesis of liver injury as a therapeutic target]. Nakamoto N. | 03/25/2017 |
that CCL25/CCR9 signal may provide cancer cells with chemotactic abilities through influencing several epithelial-mesenchymal transitionmarkers | CCL25/CCR9 Signal Promotes Migration and Invasion in Hepatocellular and Breast Cancer Cell Lines. Zhang Z, Sun T, Chen Y, Gong S, Sun X, Zou F, Peng R. | 02/4/2017 |
Studies indicate important roles played by chemokine ligand 25 (CCL25)/chemokine receptor 9 (CCR9) in tumorigenesis, tumor chemoresistance and metastasis. | CCR9 in cancer: oncogenic role and therapeutic targeting. Tu Z, Xiao R, Xiong J, Tembo KM, Deng X, Xiong M, Liu P, Wang M, Zhang Q., Free PMC Article | 10/29/2016 |
CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue. | Differential Effects of Gut-Homing Molecules CC Chemokine Receptor 9 and Integrin-β7 during Acute Graft-versus-Host Disease of the Liver. Schreder A, Moschovakis GL, Halle S, Schlue J, Lee CW, Schippers A, David S, Bernhardt G, Ganser A, Pabst O, Förster R, Koenecke C. | 08/20/2016 |
CCR9 mRNA and protein levels were significantly increased in the nasopharyngeal carcinoma group compared with the control group. | Intracellular expression profile and clinical significance of the CCR9-CCL25 chemokine receptor complex in nasopharyngeal carcinoma. Ye LF, Huang J, Zhang LP, Chen Z. | 05/7/2016 |