| Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue. | Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF., Free PMC Article | 02/23/2024 |
| Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma. | Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma.
Ostrovsky O, Beider K, Magen H, Leiba M, Sanderson RD, Vlodavsky I, Nagler A., Free PMC Article | 10/20/2023 |
| Heparanase promotes malignant phenotypes of human oral squamous carcinoma cells by regulating the epithelial-mesenchymal transition-related molecules and infiltrated levels of natural killer cells. | Heparanase promotes malignant phenotypes of human oral squamous carcinoma cells by regulating the epithelial-mesenchymal transition-related molecules and infiltrated levels of natural killer cells.
Wang C, Huang Y, Jia B, Huang Y, Chen J. | 08/14/2023 |
| Ethnic differences in urinary monocyte chemoattractant protein-1 and heparanase-1 levels in individuals with type 2 diabetes: the HELIUS study. | Ethnic differences in urinary monocyte chemoattractant protein-1 and heparanase-1 levels in individuals with type 2 diabetes: the HELIUS study.
van der Velden AIM, van den Berg BM, van den Born BJ, Galenkamp H, Ijpelaar DHT, Rabelink TJ., Free PMC Article | 01/11/2023 |
| Single-Cell Sequencing Analysis and Multiple Machine Learning Methods Identified G0S2 and HPSE as Novel Biomarkers for Abdominal Aortic Aneurysm. | Single-Cell Sequencing Analysis and Multiple Machine Learning Methods Identified G0S2 and HPSE as Novel Biomarkers for Abdominal Aortic Aneurysm.
Xiong T, Lv XS, Wu GJ, Guo YX, Liu C, Hou FX, Wang JK, Fu YF, Liu FQ., Free PMC Article | 07/9/2022 |
| Heparanase-Induced Activation of AKT Stabilizes beta-Catenin and Modulates Wnt/beta-Catenin Signaling during Herpes Simplex Virus 1 Infection. | Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection.
Koujah L, Madavaraju K, Agelidis AM, Patil CD, Shukla D., Free PMC Article | 03/12/2022 |
| Insulin-like growth factor 2 mRNA binding protein 2 regulates proliferation, migration, and angiogenesis of keratinocytes by modulating heparanase stability. | Insulin-like growth factor 2 mRNA binding protein 2 regulates proliferation, migration, and angiogenesis of keratinocytes by modulating heparanase stability.
Zhi S, Li J, Kong X, Xie X, Zhang Q, Fang G., Free PMC Article | 02/19/2022 |
| CMV Seropositive Status Increases Heparanase SNPs Regulatory Activity, Risk of Acute GVHD and Yield of CD34(+) Cell Mobilization. | CMV Seropositive Status Increases Heparanase SNPs Regulatory Activity, Risk of Acute GVHD and Yield of CD34(+) Cell Mobilization.
Ostrovsky O, Beider K, Morgulis Y, Bloom N, Cid-Arregui A, Shimoni A, Vlodavsky I, Nagler A., Free PMC Article | 01/8/2022 |
| The Heparanase Regulatory Network in Health and Disease. | The Heparanase Regulatory Network in Health and Disease.
Mayfosh AJ, Nguyen TK, Hulett MD., Free PMC Article | 01/1/2022 |
| Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma. | Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma.
Si J, Li W, Li X, Cao L, Chen Z, Jiang Z., Free PMC Article | 09/18/2021 |
| Upregulation of Fecal Epithelial Heparanase mRNA Is Associated with Increased Ulcerative Colitis Activity and Cancerization Risk. | Upregulation of Fecal Epithelial Heparanase mRNA Is Associated with Increased Ulcerative Colitis Activity and Cancerization Risk.
Cui Y, Zhang J, Chen Y, Chen LG., Free PMC Article | 09/4/2021 |
| Significance of host heparanase in promoting tumor growth and metastasis. | Significance of host heparanase in promoting tumor growth and metastasis.
Zhang GL, Gutter-Kapon L, Ilan N, Batool T, Singh K, Digre A, Luo Z, Sandler S, Shaked Y, Sanderson RD, Wang XM, Li JP, Vlodavsky I., Free PMC Article | 08/28/2021 |
| Heparanase as a potential player in SARS-CoV-2 infection and induced coagulopathy. | Heparanase as a potential player in SARS-CoV-2 infection and induced coagulopathy.
Kinaneh S, Khamaysi I, Karram T, Hamoud S., Free PMC Article | 07/17/2021 |
| Heparanase from triplenegative breast cancer and platelets acts as an enhancer of metastasis. | Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis.
Yang WJ, Zhang GL, Cao KX, Liu XN, Wang XM, Yu MW, Li JP, Yang GW., Free PMC Article | 07/17/2021 |
| Correlation between heparanase gene polymorphism and susceptibility to endometrial cancer. | Correlation between heparanase gene polymorphism and susceptibility to endometrial cancer.
Cao H, Yang S, Yu X, Xi M., Free PMC Article | 06/5/2021 |
| Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelialtomesenchymal transition through the Wnt/betacatenin pathway. | Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelial‑to‑mesenchymal transition through the Wnt/β‑catenin pathway.
Wang C, Wei Y, Wang G, Zhou Y, Zhang J, Xu K., Free PMC Article | 05/8/2021 |
| Curcumin inhibits CT26 cells metastasis by decreasing heparanase expression. | Curcumin inhibits CT26 cells metastasis by decreasing heparanase expression.
Li S, Fu H, Wang Y, Wang L, Jia B, Bian Y. | 02/13/2021 |
| Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. | Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin.
Veridiano JM, Theodoro TR, Negrete BR, Petri G, da Silva Pinhal MA, de Toledo OMS. | 02/6/2021 |
| Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression. | Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression.
Rangarajan S, Richter JR, Richter RP, Bandari SK, Tripathi K, Vlodavsky I, Sanderson RD., Free PMC Article | 01/23/2021 |
| Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway. | Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway.
Wan LM, Zhang SK, Li SB, Li W, Ji SP, Gong L, Yun ZM, Zhang X, Gao HW, Zhong H, Wei CW, Bian LH, Zhuo HL, Luo Q, Li JP, Tan YX, Gong F. | 12/26/2020 |
| Heparanase, cell signaling, and viral infections. | Heparanase, cell signaling, and viral infections.
Koganti R, Suryawanshi R, Shukla D., Free PMC Article | 11/28/2020 |
| Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling. | Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling.
Kiyan Y, Tkachuk S, Kurselis K, Shushakova N, Stahl K, Dawodu D, Kiyan R, Chichkov B, Haller H., Free PMC Article | 10/31/2020 |
| In silico investigation of heparanase-correlated genes in breast cancer subtypes. | In silico investigation of heparanase-correlated genes in breast cancer subtypes.
Melo CM, Prado HP, Attie GA, Ruiz DL, Girão MJBC, Pinhal MADS., Free PMC Article | 10/24/2020 |
| New Advances of Heparanase in Human Diseases. | New Advances of Heparanase in Human Diseases.
Jin H, Cui M. | 10/24/2020 |
| Heparanase-Regulated Syndecan-1 Shedding Facilitates Herpes Simplex Virus 1 Egress. | Heparanase-Regulated Syndecan-1 Shedding Facilitates Herpes Simplex Virus 1 Egress.
Hadigal S, Koganti R, Yadavalli T, Agelidis A, Suryawanshi R, Shukla D., Free PMC Article | 09/5/2020 |