| EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signallingdagger. | EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signalling†.
Zhang H, Kong L, Cao Z, Zhu Y, Jiang Y, Wang X, Jiang R, Liu Y, Zhou J, Kang Y, Zhen X, Kong N, Wu M, Yan G, Sun H. | 03/18/2024 |
| EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis. | EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis.
Chakraborty S, Bhat AM, Mushtaq I, Luan H, Kalluchi A, Mirza S, Storck MD, Chaturvedi N, Lopez-Guerrero JA, Llombart-Bosch A, Machado I, Scotlandi K, Meza JL, Ghosal G, Coulter DW, Jordan Rowley M, Band V, Mohapatra BC, Band H., Free PMC Article | 09/8/2023 |
| EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole. | EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.
Xie S, Naslavsky N, Caplan S., Free PMC Article | 06/14/2023 |
| EHD1 promotes the cancer stem cell (CSC)-like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation. | EHD1 promotes the cancer stem cell (CSC)-like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation.
Lu Y, Wang W, Tan S. | 08/13/2022 |
| A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness. | A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.
Issler N, Afonso S, Weissman I, Jordan K, Cebrian-Serrano A, Meindl K, Dahlke E, Tziridis K, Yan G, Robles-López JM, Tabernero L, Patel V, Kesselheim A, Klootwijk ED, Stanescu HC, Dumitriu S, Iancu D, Tekman M, Mozere M, Jaureguiberry G, Outtandy P, Russell C, Forst AL, Sterner C, Heinl ES, Othmen H, Tegtmeier I, Reichold M, Schiessl IM, Limm K, Oefner P, Witzgall R, Fu L, Theilig F, Schilling A, Shuster Biton E, Kalfon L, Fedida A, Arnon-Sheleg E, Ben Izhak O, Magen D, Anikster Y, Schulze H, Ziegler C, Lowe M, Davies B, Böckenhauer D, Kleta R, Falik Zaccai TC, Warth R., Free PMC Article | 04/9/2022 |
| A feedback circuit comprising EHD1 and 14-3-3zeta sustains beta-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer. | A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer.
Huang J, Tian F, Song Y, Cao M, Yan S, Lan X, Cui Y, Cui Y, Cui Y, Jia D, Cai L, Xing Y, Wang X. | 01/8/2022 |
| Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4. | Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4.
Lin YS, Huang KY, Yu HC, Lu MC, Fan CJ, Huang Tseng HY, Jhuang BY, Liu SQ, Lai NS, Lin TH, Huang HB. | 03/13/2021 |
| EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases. | EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases.
Martins-Marques T, Catarino S, Gonçalves A, Miranda-Silva D, Gonçalves L, Antunes P, Coutinho G, Leite Moreira A, Falcão Pires I, Girão H. | 02/27/2021 |
| Eps15 Homology Domain Protein 4 (EHD4) is required for Eps15 Homology Domain Protein 1 (EHD1)-mediated endosomal recruitment and fission. | Eps15 Homology Domain Protein 4 (EHD4) is required for Eps15 Homology Domain Protein 1 (EHD1)-mediated endosomal recruitment and fission.
Jones T, Naslavsky N, Caplan S., Free PMC Article | 11/21/2020 |
| RUSC2 and EHD1 function in a common pathway to positively regulate the basal traffic of Epidermal growth factor receptor from the Golgi compartment to the cell surface to ensure optimal surface receptor levels for subsequent ligand-mediated activation and cellular responses. | EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling.
Tom EC, Mushtaq I, Mohapatra BC, Luan H, Bhat AM, Zutshi N, Chakraborty S, Islam N, Arya P, Bielecki TA, Iseka FM, Bhattacharyya S, Cypher LR, Goetz BT, Negi SK, Storck MD, Rana S, Barnekow A, Singh PK, Ying G, Guda C, Natarajan A, Band V, Band H., Free PMC Article | 08/1/2020 |
| Data support the notion that a pool of centriolar gamma-tubulin and/or alpha-tubulin-beta-tubulin heterodimers anchor MICAL-L1 to the centriole, where it might recruit EHD1 to promote ciliogenesis. | MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium.
Xie S, Farmer T, Naslavsky N, Caplan S., Free PMC Article | 07/25/2020 |
| aberrant EHD1 signaling in the endometrium of RIF patients contributes to impaired decidualization and ultimately to implantation failure. EHD1 interacts with Wnt4, and this interaction leads to the suppression of Wnt4/beta-catenin signaling and impaired decidualization | EHD1 impairs decidualization by regulating the Wnt4/β-catenin signaling pathway in recurrent implantation failure.
Zhou Q, Yan G, Ding L, Liu J, Yu X, Kong S, Zhang M, Wang Z, Liu Y, Jiang Y, Kong N, Sun J, Sun H., Free PMC Article | 05/2/2020 |
| EHD1 may be an independent prognostic marker in lung cancer and that the NF-kappaB/miR-590/EHD1 signalling pathway might be a potentially effective therapy for overcoming EGFR-TKI resistance. | NF-κB-driven improvement of EHD1 contributes to erlotinib resistance in EGFR-mutant lung cancers.
Wang X, Yin H, Zhang H, Hu J, Lu H, Li C, Cao M, Yan S, Cai L., Free PMC Article | 03/28/2020 |
| The expression of EHD1 was negatively correlated with disease-free survival and overall survival of osteosarcoma patients. | The expression of Eps15 homology domain 1 is negatively correlated with disease-free survival and overall survival of osteosarcoma patients.
Yu H, Qu G, Wang Y, Mai W, Bao JJ, Song C, Yao M., Free PMC Article | 09/7/2019 |
| the data obtained in this study suggest that EHD1 plays a critical role in Non-small cell lung cancer (NSCLC) angiogenesis via b2AR signaling and highlight a potential target for antiangiogenic therapy. | Mammalian Eps15 homology domain 1 potentiates angiogenesis of non-small cell lung cancer by regulating β2AR signaling.
Wang T, Xing Y, Meng Q, Lu H, Liu W, Yan S, Song Y, Xu X, Huang J, Cui Y, Jia D, Cai L., Free PMC Article | 08/17/2019 |
| Depletion of myosin-Va significantly inhibits the attachment of preciliary vesicles to the distal appendages of the mother centriole and decreases cilia assembly. Myosin-Va functions upstream of EHD1- and Rab11-mediated ciliary vesicle formation. | Myosin-Va is required for preciliary vesicle transportation to the mother centriole during ciliogenesis.
Wu CT, Chen HY, Tang TK. | 04/13/2019 |
| PACSIN1 and EHD1 assemble membrane tubules from the developing intracellular cilium that attach to the plasma membrane, creating an extracellular membrane channel to the outside of the cell. | Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport.
Insinna C, Lu Q, Teixeira I, Harned A, Semler EM, Stauffer J, Magidson V, Tiwari A, Kenworthy AK, Narayan K, Westlake CJ., Free PMC Article | 02/16/2019 |
| Results suggest that EHD1 is a cisplatin (CDDP)-resistant gene that suppresses DNA adduct-induced apoptosis by modulating intracellular CDDP concentrations. | EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations.
Gao J, Meng Q, Zhao Y, Chen X, Cai L., Free PMC Article | 10/7/2017 |
| this study shows that overexpression of EHD1 induced the epithelial-mesenchymal transition and increased the metastatic potential of lung cancer cells in vitro and in vivo | Mammalian Eps15 homology domain 1 promotes metastasis in non-small cell lung cancer by inducing epithelial-mesenchymal transition.
Meng Q, Xing Y, Ren T, Lu H, Xi Y, Jiang Z, Hu J, Li C, Sun L, Sun D, Cai L., Free PMC Article | 09/16/2017 |
| RAB11FIP3 combines with Eps15 homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor. | Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling.
Tong D, Liang YN, Stepanova AA, Liu Y, Li X, Wang L, Zhang F, Vasilyeva NV. | 03/4/2017 |
| van der Waals interactions should be the main consideration when we design peptide inhibitors of EHD1 EH domain with high affinities. | Molecular dynamics simulation of the interactions between EHD1 EH domain and multiple peptides.
Yu H, Wang MJ, Xuan NX, Shang ZC, Wu J., Free PMC Article | 07/30/2016 |
| Authors found that Eps15-homology domain 1 (EHD1), a protein that associates with the endocytic recycling compartment (ERC), colocalizes with active R-Ras in transiently expressed HeLa cells. | ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment.
Salem JC, Reviriego-Mendoza MM, Santy LC., Free PMC Article | 07/30/2016 |
| that Molecule Interacting with CasL Like-1 and Eps15 Homology Domain protein 1 differentially influence microtubule dynamics during early and late mitosis | Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.
Reinecke JB, Katafiasz D, Naslavsky N, Caplan S., Free PMC Article | 01/30/2016 |
| Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. | Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.
Lee S, Uchida Y, Wang J, Matsudaira T, Nakagawa T, Kishimoto T, Mukai K, Inaba T, Kobayashi T, Molday RS, Taguchi T, Arai H., Free PMC Article | 05/9/2015 |
| Data indicate that concordant transforming growth factor-beta1 (TGFbeta-1) positive and EH-domain containing 1 (EHD1) negative as a strong favorable prognosis factor in non-small cell lung cancer (NSCLC). | Expression of TGFβ-1 and EHD1 correlated with survival of non-small cell lung cancer.
Gao Y, Wang Y, Sun L, Meng Q, Cai L, Dong X. | 01/3/2015 |