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    UPK1A uroplakin 1A [ Homo sapiens (human) ]

    Gene ID: 11045, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1.

    Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1.
    Munipalli SB, Yenugu S.

    12/5/2023
    Large-scale human tissue analysis identifies Uroplakin 1a as a putative diagnostic marker for urothelial cancer.

    Large-scale human tissue analysis identifies Uroplakin 1a as a putative diagnostic marker for urothelial cancer.
    Reiswich V, Könemann S, Lennartz M, Höflmayer D, Menz A, Chirico V, Hube-Magg C, Fraune C, Bernreuther C, Simon R, Clauditz TS, Sauter G, Hinsch A, Kind S, Jacobsen F, Steurer S, Minner S, Büscheck F, Burandt E, Marx AH, Lebok P, Krech T.

    10/29/2022
    Long Noncoding RNA Expression Profiling Reveals Upregulation of Uroplakin 1A and Uroplakin 1A Antisense RNA 1 under Hypoxic Conditions in Lung Cancer Cells.

    Long Noncoding RNA Expression Profiling Reveals Upregulation of Uroplakin 1A and Uroplakin 1A Antisense RNA 1 under Hypoxic Conditions in Lung Cancer Cells.
    Byun Y, Choi YC, Jeong Y, Yoon J, Baek K., Free PMC Article

    07/31/2021
    Down-regulation of UPK1A suppresses proliferation and enhances apoptosis of bladder transitional cell carcinoma cells.

    Downregulation of UPK1A suppresses proliferation and enhances apoptosis of bladder transitional cell carcinoma cells.
    Zhu H, Tang Y, Zhang X, Jiang X, Wang Y, Gan Y, Yang J.

    03/19/2016
    expression of UPKIa was a promising predictor for poor outcome of colorectal cancer patients

    Decreased expression of uroplakin Ia is associated with colorectal cancer progression and poor survival of patients.
    He Y, Kong F, Du H, Wu M., Free PMC Article

    06/20/2015
    Reduced expression of uroplakin 1A is associated with gastric adenocarcinoma.

    Reduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.
    Zheng Y, Wang DD, Wang W, Pan K, Huang CY, Li YF, Wang QJ, Yuan SQ, Jiang SS, Qiu HB, Chen YM, Zhang XF, Zhao BW, Mai C, Xia JC, Zhou ZW., Free PMC Article

    01/31/2015
    Loss of UPK1A is associated with esophageal squamous cell carcinoma.

    Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma.
    Kong KL, Kwong DL, Fu L, Chan TH, Chen L, Liu H, Li Y, Zhu YH, Bi J, Qin YR, Law SY, Guan XY.

    01/1/2011
    The authors show by cryo-electron microscopy that FimH binding to the extracellular domain of UP Ia induces global conformational changes in the entire UP receptor complex, including a coordinated movement of the tightly bundled transmembrane helices.

    Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: implications in transmembrane signaling transduction.
    Wang H, Min G, Glockshuber R, Sun TT, Kong XP., Free PMC Article

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)

    Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
    Jiang S, Gitlin J, Deng FM, Liang FX, Lee A, Atala A, Bauer SB, Ehrlich GD, Feather SA, Goldberg JD, Goodship JA, Goodship TH, Hermanns M, Hu FZ, Jones KE, Malcolm S, Mendelsohn C, Preston RA, Retik AB, Schneck FX, Wright V, Ye XY, Woolf AS, Wu XR, Ostrer H, Shapiro E, Yu J, Sun TT.

    03/13/2008
    uroplakin Ia is expressed in urinary bladder transitional cell carcinoma

    High expression of human uroplakin Ia in urinary bladder transitional cell carcinoma.
    Kageyama S, Yoshiki T, Isono T, Tanaka T, Kim CJ, Yuasa T, Okada Y., Free PMC Article

    01/21/2010
    determined the genomic structure of the uroplakin Ia gene and defined the position of a transcriptional start site

    Transcriptional control of the human urothelial-specific gene, uroplakin Ia.
    Hall GD, Weeks RJ, Olsburgh J, Southgate J, Knowles MA, Selby PJ, Chester JD.

    01/21/2010
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