| FOXM1 and CHD4 expression is associated with chemoresistance in hepatoblastoma. | FOXM1 and CHD4 expression is associated with chemoresistance in hepatoblastoma.
Hino Y, Kohashi K, Tamaki A, Kawakubo N, Hamada H, Fukuhara M, Shibui Y, Tajiri T, Oda Y. | 05/30/2024 |
| CHD4 and SMYD1 repress common transcriptional programs in the developing heart. | CHD4 and SMYD1 repress common transcriptional programs in the developing heart.
Shi W, Wasson LK, Dorr KM, Robbe ZL, Wilczewski CM, Hepperla AJ, Davis IJ, Seidman CE, Seidman JG, Conlon FL., Free PMC Article | 05/23/2024 |
| Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4. | Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4.
Saotome M, Poduval DB, Grimm SA, Nagornyuk A, Gunarathna S, Shimbo T, Wade PA, Takaku M., Free PMC Article | 05/8/2024 |
| Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/beta-catenin pathway inhibition. | Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition.
Xiao G, Lu W, Yuan J, Liu Z, Wang P, Fan H., Free PMC Article | 02/6/2024 |
| The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture. | The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture.
Graca Marques J, Pavlovic B, Ngo QA, Pedot G, Roemmele M, Volken L, Kisele S, Perbet R, Wachtel M, Schäfer BW. | 01/29/2024 |
| Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line. | Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line.
Moraes-Almeida MS, Sogayar MC, Demasi MAA., Free PMC Article | 11/21/2023 |
| The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for beta-Cell Function In Vivo. | The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
Davidson RK, Kanojia S, Wu W, Kono T, Xu J, Osmulski M, Bone RN, Casey N, Evans-Molina C, Sims EK, Spaeth JM., Free PMC Article | 08/25/2023 |
| Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA. | Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA.
Guel T, Scholtissek B, Siegl J, Fetter T, Mayer G, Bieber T, Wenzel J. | 07/13/2023 |
| Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. | Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1.
Shi W, Scialdone AP, Emerson JI, Mei L, Wasson LK, Davies HA, Seidman CE, Seidman JG, Cook JG, Conlon FL., Free PMC Article | 06/28/2023 |
| Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4. | Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.
Strathmann EA, Hölker I, Tschernoster N, Hosseinibarkooie S, Come J, Martinat C, Altmüller J, Wirth B., Free PMC Article | 03/8/2023 |
| The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/beta-catenin axis and acts as a therapeutic target in ovarian cancer. | The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/β-catenin axis and acts as a therapeutic target in ovarian cancer.
Wang J, Zhong F, Li J, Yue H, Li W, Lu X., Free PMC Article | 02/11/2023 |
| KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4. | KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.
Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, Wang KH, Inagaki T, Chuang F, Davis RR, Tepper CG, Nakano K, Izumiya C, Shimoda M, Nakajima KI, Merleev A, Zheng ZM, Campbell M, Izumiya Y., Free PMC Article | 06/11/2022 |
| CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer. | CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer.
Chang CL, Huang CR, Chang SJ, Wu CC, Chen HH, Luo CW, Yip HK., Free PMC Article | 04/2/2022 |
| CHD4 variants are associated with childhood idiopathic epilepsy with sinus arrhythmia. | CHD4 variants are associated with childhood idiopathic epilepsy with sinus arrhythmia.
Liu XR, Ye TT, Zhang WJ, Guo X, Wang J, Huang SP, Xie LS, Song XW, Deng WW, Li BM, He N, Wu QY, Zhuang MZ, Xu M, Shi YW, Su T, Yi YH, Liao WP, China Epilepsy Gene 1.0 Project., Free PMC Article | 01/29/2022 |
| CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents. | CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents.
Oyama Y, Shigeta S, Tokunaga H, Tsuji K, Ishibashi M, Shibuya Y, Shimada M, Yasuda J, Yaegashi N., Free PMC Article | 10/30/2021 |
| CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells. | CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells.
Pratheeshkumar P, Siraj AK, Divya SP, Parvathareddy SK, Alobaisi K, Al-Sobhi SS, Al-Dayel F, Al-Kuraya KS., Free PMC Article | 09/18/2021 |
| Knockdown of circ_0006528 Suppresses Cell Proliferation, Migration, Invasion, and Adriamycin Chemoresistance via Regulating the miR-1236-3p/CHD4 Axis in Breast Cancer. | Knockdown of circ_0006528 Suppresses Cell Proliferation, Migration, Invasion, and Adriamycin Chemoresistance via Regulating the miR-1236-3p/CHD4 Axis in Breast Cancer.
Hao J, Du X, Lv F, Shi Q. | 09/11/2021 |
| ZNF410 represses fetal globin by singular control of CHD4. | ZNF410 represses fetal globin by singular control of CHD4.
Vinjamur DS, Yao Q, Cole MA, McGuckin C, Ren C, Zeng J, Hossain M, Luk K, Wolfe SA, Pinello L, Bauer DE., Free PMC Article | 06/19/2021 |
| The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy. | The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.
Pinard A, Guey S, Guo D, Cecchi AC, Kharas N, Wallace S, Regalado ES, Hostetler EM, Sharrief AZ, Bergametti F, Kossorotoff M, Hervé D, Kraemer M, Bamshad MJ, Nickerson DA, Smith ER, Tournier-Lasserve E, Milewicz DM., Free PMC Article | 03/27/2021 |
| Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations. | Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations.
Farnung L, Ochmann M, Cramer P., Free PMC Article | 02/20/2021 |
| NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency. | NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.
Marques JG, Gryder BE, Pavlovic B, Chung Y, Ngo QA, Frommelt F, Gstaiger M, Song Y, Benischke K, Laubscher D, Wachtel M, Khan J, Schäfer BW., Free PMC Article | 02/13/2021 |
| ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. | ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, Crossley M, Weiss MJ, Cheng X, Shi J, Blobel GA., Free PMC Article | 02/6/2021 |
| [Clinical and genetic analysis of a novel CHD4 gene variant in a Chinese patient with Sifrim-Hitz-Weiss syndrome]. | [Clinical and genetic analysis of a novel CHD4 gene variant in a Chinese patient with Sifrim-Hitz-Weiss syndrome].
Zhou X, Wang Q, Liu Y, Liu J, Yuan H. | 01/30/2021 |
| CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors. | CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors.
Wang Y, Chen Y, Bao L, Zhang B, Wang JE, Kumar A, Xing C, Wang Y, Luo W., Free PMC Article | 01/16/2021 |
| CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A. | CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A.
Xu N, Liu F, Wu S, Ye M, Ge H, Zhang M, Song Y, Tong L, Zhou J, Bai C., Free PMC Article | 12/12/2020 |