Chitinase 3-like-1 Inhibits Innate Antitumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα- and CD24-Siglec10-Mediated Phagocytosis.
Ma B, Kamle S, Sadanaga T, Lee CM, Lee JH, Yee DC, Zhu Z, Silverman EK, DeMeo DL, Choi AMK, Lee CG, Elias JA.

YKL40/Integrin β4 Axis Induced by the Interaction between Cancer Cells and Tumor-Associated Macrophages Is Involved in the Progression of High-Grade Serous Ovarian Carcinoma.
Yamanaka K, Koma YI, Urakami S, Takahashi R, Nagamata S, Omori M, Torigoe R, Yokoo H, Nakanishi T, Ishihara N, Tsukamoto S, Kodama T, Nishio M, Shigeoka M, Yokozaki H, Terai Y., Free PMC Article

Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus.
Song Y, Jiang W, Afridi SK, Wang T, Zhu F, Xu H, Nazir FH, Liu C, Wang Y, Long Y, Huang YA, Qiu W, Tang C.

Serum YKL-40 and Serum Krebs von den Lungen-6 as Potential Predictive Biomarkers for Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Liang B, Zhang Y, Ke D, Yan R, Jiang MN, Li L, Zhang LX, Zhao XG, Yuan GP, Xu B, Liu XM.

YKL-40 Knockdown Decreases Oxidative Stress Damage in Ovarian Granulosa Cells.
Tang T, Gao J, Pan X, Tang Q, Long H, Liu Z.

Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation.
Mizoguchi E, Sadanaga T, Nanni L, Wang S, Mizoguchi A., Free PMC Article

YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability.
Wang C, Liu Y, Huan W, Wu J, Jin J, Zou S, Chen Y, Qu L., Free PMC Article

Functional variants of the chitinase 3-like 1 gene are associated with clinicopathologic outcomes and progression of prostate cancer.
Wen YC, Lin CY, Ho KH, Lin YW, Hsiao CH, Wang SS, Chang LC, Yang SF, Chien MH., Free PMC Article

TIMP1/CHI3L1 facilitates glioma progression and immunosuppression via NF-κB activation.
Xu J, Wei C, Wang C, Li F, Wang Z, Xiong J, Zhou Y, Li S, Liu X, Yang G, Han L, Zhang J, Zhang S.

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1.
Hai L, Hoffmann DC, Wagener RJ, Azorin DD, Hausmann D, Xie R, Huppertz MC, Hiblot J, Sievers P, Heuer S, Ito J, Cebulla G, Kourtesakis A, Kaulen LD, Ratliff M, Mandelbaum H, Jung E, Jabali A, Horschitz S, Ernst KJ, Reibold D, Warnken U, Venkataramani V, Will R, Suvà ML, Herold-Mende C, Sahm F, Winkler F, Schlesner M, Wick W, Kessler T., Free PMC Article

Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia.
Pase MP, Himali JJ, Puerta R, Beiser AS, Gonzales MM, Satizabal CL, Yang Q, Aparicio HJ, Kojis DJ, Decarli CS, Lopez OL, Longstreth W, Gudnason V, Mosley TH, Bis JC, Fohner A, Psaty BM, Boada M, García-González P, Valero S, Marquié M, Tracy R, Launer LJ, Ruiz A, Fornage M, Seshadri S.,

Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression.
Pelkmans W, Shekari M, Brugulat-Serrat A, Sánchez-Benavides G, Minguillón C, Fauria K, Molinuevo JL, Grau-Rivera O, González Escalante A, Kollmorgen G, Carboni M, Ashton NJ, Zetterberg H, Blennow K, Suarez-Calvet M, Gispert JD, ALFA study., Free PMC Article

An Association of Chitinase-3 Like-Protein-1 With Neuronal Deterioration in Multiple Sclerosis.
Ahmad I, Wergeland S, Oveland E, Bø L., Free PMC Article

Clinical Significance of Chitinase-3-like Protein 1 Gene Expression in Patients With Locally Advanced Gastric Cancer.
Oshima T, Hashimoto I, Hiroshima Y, Kimura Y, Tanabe M, Onuma S, Nagasawa S, Kanematsu K, Aoyama T, Yamada T, Ogata T, Rino Y, Saito A, Miyagi Y.

The potential roles and mechanisms of Chitinase-3-like-1 in the pathogenesis of type 2-biased airway diseases.
Zhou Y, Liu Z, Liu Y.

The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer.
Taifour T, Attalla SS, Zuo D, Gu Y, Sanguin-Gendreau V, Proud H, Solymoss E, Bui T, Kuasne H, Papavasiliou V, Lee CG, Kamle S, Siegel PM, Elias JA, Park M, Muller WJ.

YKL-40 and the Cellular Metabolic Profile in Parkinson's Disease.
Gevezova M, Kazakova M, Trenova A, Sarafian V., Free PMC Article

Chitinase 3-like-1 Expression in the Microenvironment Is Associated with Neutrophil Infiltration in Bladder Cancer.
Xiao LY, Su YL, Huang SY, Chen YH, Hsueh PR., Free PMC Article

[YKL-40 Promotes the Expression of Inflammatory Factors in Type Ⅱ Alveolar Epithelial Cell Model of A549 Cell Line].
Miao Z, Ran J, Mou D, Wu S, Chen Y, Li C, Chen Y, Yang M, Xie Q., Free PMC Article

Independent Predictive Value of Elevated YKL-40 in Ischemic Stroke Prognosis: Findings from a Nationwide Stroke Registry.
Qin H, Liu G, Zhang Y, Zhang J, Wang A, Yu M, Zhang R, Lin J, Liang X, Liu L, Zhang G, Zhao X, Wang Y., Free PMC Article

Causal Effects of YKL-40 on Ischemic Stroke and Its Subtypes: A 2-Sample Mendelian Randomization Study.
Xu Q, Sun L, Wang Y, Wang R, Jia Y, Guo D, Shi M, Yang P, Zhang Y, Zhu Z., Free PMC Article

Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression.
Kim AD, Kui L, Kaufmann B, Kim SE, Leszczynska A, Feldstein AE., Free PMC Article

Chitinase 3-like 1: a Specifical Regulator of Myocardial Infarction.
Yao J, Xie J, Wang H, Vulugundam G, Wang H, Xiao J.

Induction of ER stress-mediated apoptosis through SOD1 upregulation by deficiency of CHI3L1 inhibits lung metastasis.
Yu JE, Yeo IJ, Yoo SS, Kim SH, Son DJ, Yun J, Han SB, Hong JT., Free PMC Article

YKL-40 derived from infiltrating macrophages cooperates with GDF15 to establish an immune suppressive microenvironment in gallbladder cancer.
Wang Z, Wang S, Jia Z, Hu Y, Cao D, Yang M, Liu L, Gao L, Qiu S, Yan W, Li Y, Luo J, Geng Y, Zhang J, Li Z, Wang X, Li M, Shao R, Liu Y.