| FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis. | FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.
Zhang J, Di S, Li M, Dong Y, Xie S, Gong T, Hu P, Jia Q, Fan B. | 12/5/2023 |
| FAM107A as a Tumor Suppressor in Bladder Cancer Inhibits Cell Proliferation, Migration, and Invasion. | FAM107A as a Tumor Suppressor in Bladder Cancer Inhibits Cell Proliferation, Migration, and Invasion.
Ou L, Wei Z, Xu J, Li W, Zhou Y, Wang Y, Shi B. | 04/30/2022 |
| Transcription factor SP1-induced microRNA-146b-3p facilitates the progression and metastasis of colorectal cancer via regulating FAM107A. | Transcription factor SP1-induced microRNA-146b-3p facilitates the progression and metastasis of colorectal cancer via regulating FAM107A.
Wang D, Feng M, Ma X, Tao K, Wang G. | 06/26/2021 |
| Results showed that DRR1 is overexpressed in glioblastoma multiforme (GBM) tissues. Its overexpression is associated with tumor progression and poor clinical outcome of GBM patients, which indicates that DRR1 might be a novel prognostic marker of GBM. More results indicated that DRR1 was involved in GBM invasion and progression possibly through the induction of EMT as activated by phosphorylation of AKT. | DRR1 promotes glioblastoma cell invasion and epithelial-mesenchymal transition via regulating AKT activation.
Ma YS, Wu ZJ, Bai RZ, Dong H, Xie BX, Wu XH, Hang XS, Liu AN, Jiang XH, Wang GR, Jiang JJ, Xu WH, Chen XP, Tan GH, Fu D, Liu JB, Liu Q. | 06/22/2019 |
| Both IQGAP3/BMP4 and IQGAP3/FAM107A ratios in ucfDNA were significantly higher in patients with BC than in those with hematuria. | Diagnostic value of combined IQGAP3/BMP4 and IQGAP3/FAM107A expression ratios in urinary cell-free DNA for discriminating bladder cancer from hematuria.
Xu Y, Kim YH, Jeong P, Piao XM, Byun YJ, Kang HW, Kim WT, Lee JY, Kim IY, Moon SK, Choi YH, Yun SJ, Kim WJ. | 03/9/2019 |
| FAM107A gene is down-regulated in laryngeal tumors. | Combined deletion and DNA methylation result in silencing of FAM107A gene in laryngeal tumors.
Kiwerska K, Szaumkessel M, Paczkowska J, Bodnar M, Byzia E, Kowal E, Kostrzewska-Poczekaj M, Janiszewska J, Bednarek K, Jarmuż-Szymczak M, Kalinowicz E, Wierzbicka M, Grenman R, Szyfter K, Marszałek A, Giefing M., Free PMC Article | 01/19/2019 |
| This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 that is involved in NF-kappaB degradation and cell cycle suppression in neuroblastoma cells. | A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.
Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K. | 10/28/2017 |
| Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression. | Decreased FAM107A Expression in Patients with Non-small Cell Lung Cancer.
Pastuszak-Lewandoska D, Czarnecka KH, Migdalska-Sęk M, Nawrot E, Domańska D, Kiszałkiewicz J, Kordiak J, Antczak A, Górski P, Brzeziańska-Lasota E. | 09/12/2015 |
| Results found that DRR expression leads to elevated AKT activation by recruiting AKT to focal adhesios in a manner dependent on SRC-family kinases (SFKs) and cell adhesion. | DRR regulates AKT activation to drive brain cancer invasion.
Dudley A, Sater M, Le PU, Trinh G, Sadr MS, Bergeron J, Deleavey GF, Bedell B, Damha MJ, Petrecca K. | 12/20/2014 |
| DRR1 protein is expressed in normal cells, particularly in the nervous system during embryogenesis, is involved in neuronal cell survival, and is downregulated during neuroblastoma carcinogenesis. | DRR1 is expressed in the developing nervous system and downregulated during neuroblastoma carcinogenesis.
Asano Y, Kishida S, Mu P, Sakamoto K, Murohara T, Kadomatsu K. | 05/10/2010 |
| TU3A is epigenetically inactivated in human cancer | Methylation-associated silencing of TU3A in human cancers.
Awakura Y, Nakamura E, Ito N, Kamoto T, Ogawa O. | 01/21/2010 |
| Expression of the down-regulated in renal cell carcinoma gene (DRR1) gene at 3p14.2 was lost in 7 and down regulated in 2 "chr3+" tumours. | Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice.
Kholodnyuk ID, Kozireva S, Kost-Alimova M, Kashuba V, Klein G, Imreh S. | 01/21/2010 |