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    NOSTRIN nitric oxide synthase trafficking [ Homo sapiens (human) ]

    Gene ID: 115677, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Nitric-Oxide Synthase trafficking inducer (NOSTRIN) is an emerging negative regulator of colon cancer progression.

    Nitric-Oxide Synthase trafficking inducer (NOSTRIN) is an emerging negative regulator of colon cancer progression.
    Paul M, Gope TK, Das P, Ain R., Free PMC Article

    06/11/2022
    The suggest that scores obtained with the worst nostril are the most efficient in detecting an olfactory disorder.

    Nostril Differences in the Olfactory Performance in Health and Disease.
    Poupon D, Hummel T, Haehner A, Welge-Luessen A, Frasnelli J.

    01/20/2018
    NOSTRIN inhibited production of nitric oxide (NO) by suppressing the activation of endothelial nitric oxide synthase (eNOS).

    Endothelial Nitric Oxide Synthase Traffic Inducer (NOSTRIN) is a Negative Regulator of Disease Aggressiveness in Pancreatic Cancer.
    Wang J, Yang S, He P, Schetter AJ, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Gaida MM, Hanna N, Alexander HR, Hussain SP., Free PMC Article

    01/13/2018
    no significant difference in serum level associated with preeclampsia or intrauterine growth restriction

    The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction.
    Laskowska M, Laskowska K, Oleszczuk J.

    01/16/2016
    This study showed that overexpression of NOSTRIN had a significant effect on eNOS activity in HUVECs and resulted in significant cellular damage.

    Changes in human umbilical vein endothelial cells induced by endothelial nitric oxide synthase traffic inducer.
    Xu XY, Pang WJ, Wen ZN, Xiang WP.

    09/13/2014
    The expression of NOSTRIN is decreased, while the activity of eNOS and the level of NO2-/NO3- increased in the testis tissue of azoospermia patients.

    [Expression of NOSTRIN in the testis tissue of azoospermia patients].
    Xiang WP, Wen ZN, Hu L, Li HG, Xiong CL.

    11/19/2011
    Results reveal an elegant mechanism of eNOS regulation by PECAM-1 through signal transducers and activators of transcription 3-mediated transcriptional control of NOSTRIN.

    Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression.
    McCormick ME, Goel R, Fulton D, Oess S, Newman D, Tzima E., Free PMC Article

    04/9/2011
    NOSTRIN expression was increased in umbilical vessel of women with pre-eclampsia.

    Endothelial nitric oxide synthase traffic inducer in the umbilical vessels of the patients with pre-eclampsia.
    Xiang W, Chen H, Hu L, Xu X.

    03/19/2011
    Observational study and meta-analysis of gene-disease association. (HuGE Navigator)

    Linkage and candidate gene studies of autism spectrum disorders in European populations.
    Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojärvi K, Järvelä I, Klauck SM, Poustka F, Bailey AJ, Monaco AP, EU Autism MOLGEN Consortium., Free PMC Article

    06/30/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Observational study of gene-disease association. (HuGE Navigator)

    High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
    Maestrini E, Pagnamenta AT, Lamb JA, Bacchelli E, Sykes NH, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri TS, Minopoli F, Reichert J, Cai G, Buxbaum JD, Korvatska O, Schellenberg GD, Dawson G, de Bildt A, Minderaa RB, Mulder EJ, Morris AP, Bailey AJ, Monaco AP, IMGSAC., Free PMC Article

    05/17/2009
    results suggest that nuclear NOSTRINbeta may negatively regulate transcription of the NOSTRIN gene

    NOSTRINbeta--a shortened NOSTRIN variant with a role in transcriptional regulation.
    Wiesenthal A, Hoffmeister M, Siddique M, Kovacevic I, Oess S, Müller-Esterl W, Siehoff-Icking A.

    01/21/2010
    NOSTRIN modulates nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.

    NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.
    Zimmermann K, Opitz N, Dedio J, Renne C, Muller-Esterl W, Oess S., Free PMC Article

    01/21/2010
    NOSTRIN may facilitate endocytosis of endothelial nitric oxide synthase by coordinating the function of dynamin and the actin nucleation promoting factor N-WASP.

    NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS.
    Icking A, Matt S, Opitz N, Wiesenthal A, Müller-Esterl W, Schilling K.

    01/21/2010
    A ternary complex between NOSTRIN, caveolin-1, and eNOS mediates translocation of eNOS, with important implications for the activity and availability of eNOS in the cell.

    Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.
    Schilling K, Opitz N, Wiesenthal A, Oess S, Tikkanen R, Müller-Esterl W, Icking A., Free PMC Article

    01/21/2010
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