| Exosomal miR-361-3p promotes the viability of breast cancer cells by targeting ETV7 and BATF2 to upregulate the PAI-1/ERK pathway. | Exosomal miR-361-3p promotes the viability of breast cancer cells by targeting ETV7 and BATF2 to upregulate the PAI-1/ERK pathway.
Li Y, Fan L, Yan A, Ren X, Zhao Y, Hua B., Free PMC Article | 03/1/2024 |
| BATF2 inhibits PD-L1 expression and regulates CD8+ T-cell infiltration in non-small cell lung cancer. | BATF2 inhibits PD-L1 expression and regulates CD8+ T-cell infiltration in non-small cell lung cancer.
Liu J, Li J, Tuo Z, Hu W, Liu J., Free PMC Article | 11/30/2023 |
| Nuclear export of BATF2 enhances colorectal cancer proliferation through binding to CRM1. | Nuclear export of BATF2 enhances colorectal cancer proliferation through binding to CRM1.
Zhou J, Lei Z, Chen J, Liao S, Chen Y, Liu C, Huang S, Li L, Zhang Y, Wang P, Huang Y, Li J, Liang H., Free PMC Article | 10/28/2023 |
| Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype. | Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype.
Zsurka G, Appel MLT, Nastaly M, Hallmann K, Hansen N, Nass D, Baumgartner T, Surges R, Hartmann G, Bartok E, Kunz WS., Free PMC Article | 02/11/2023 |
| m6A modification-mediated BATF2 suppresses metastasis and angiogenesis of tongue squamous cell carcinoma through inhibiting VEGFA. | m6A modification-mediated BATF2 suppresses metastasis and angiogenesis of tongue squamous cell carcinoma through inhibiting VEGFA.
Wen H, Tang J, Cui Y, Hou M, Zhou J., Free PMC Article | 12/24/2022 |
| SARI inhibits growth and reduces survival of oral squamous cell carcinomas (OSCC) by inducing endoplasmic reticulum stress. | SARI inhibits growth and reduces survival of oral squamous cell carcinomas (OSCC) by inducing endoplasmic reticulum stress.
Priyadarshini M, Maji S, Samal SK, Rath R, Li J, Das SK, Emdad L, Kundu CN, Fisher PB, Dash R. | 12/18/2021 |
| Expression and clinical implications of basic leucine zipper ATF-like transcription factor 2 in breast cancer. | Expression and clinical implications of basic leucine zipper ATF-like transcription factor 2 in breast cancer.
Lin Y, Zhou X, Peng W, Wu J, Wu X, Chen Y, Cui Z., Free PMC Article | 10/23/2021 |
| BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells. | BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells.
Zhang X, Liu Y, Dai L, Shi G, Deng J, Luo Q, Xie Q, Cheng L, Li C, Lin Y, Wang Q, Fan P, Zhang H, Su X, Zhang S, Yang Y, Hu X, Gong Q, Yu D, Zheng L, Deng H., Free PMC Article | 07/31/2021 |
| BATF2 expression as a novel marker for invasive phenotype in malignant melanoma. | BATF2 expression as a novel marker for invasive phenotype in malignant melanoma.
Tagawa H, Kanemaru H, Kimura T, Kuriyama H, Sawamura S, Kajihara I, Miyashita A, Aoi J, Fukushima S, Ihn H. | 07/24/2021 |
| miRNA-765 mediates multidrug resistance via targeting BATF2 in gastric cancer cells. | miRNA-765 mediates multidrug resistance via targeting BATF2 in gastric cancer cells.
Lin W, Miao Y, Meng X, Huang Y, Zhao W, Ruan J., Free PMC Article | 07/24/2021 |
| BATF2 balances the T cell-mediated immune response of CADM with an anti-MDA5 autoantibody. | BATF2 balances the T cell-mediated immune response of CADM with an anti-MDA5 autoantibody.
Li C, Liu M, Liu K, Li M, Liu Y, Li T, Wei Y, Long Y, He W, Shi X, Li Y, Zhang H. | 07/3/2021 |
| m(6)A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling. | m(6)A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling.
Xie JW, Huang XB, Chen QY, Ma YB, Zhao YJ, Liu LC, Wang JB, Lin JX, Lu J, Cao LL, Lin M, Tu RH, Zheng CH, Huang CM, Li P., Free PMC Article | 05/29/2021 |
| SARI prevents ocular angiogenesis and inflammation in mice. | SARI prevents ocular angiogenesis and inflammation in mice.
Zhang W, Dai L, Li X, Li Y, Hung Yap MK, Liu L, Deng H., Free PMC Article | 05/1/2021 |
| BATF2 was overexpressed in tissues from patients with non-responsive gastric cancer (GC) and the vincristine resistance cell line, SGC7901/VCR, while levels of c-Fos and c-Jun were reduced. AP-1 down-regulation by BATF2 overexpression or AP-1 knockdown can inhibit drug resistance in GC cells. These findings suggest that BATF2 inhibits DR in vincristine resistance GC cell line by down-regulating AP-1 expression. | BATF2 inhibits chemotherapy resistance by suppressing AP-1 in vincristine-resistant gastric cancer cells.
Yang W, Zhao S, Wu B, Xu J, Wu Z, Guo J, Zeng R. | 05/30/2020 |
| BATF2 role in the multidrug resistance of human gastric cancer cells and the regulation of the Wnt/beta-catenin signaling. | BATF2 reverses multidrug resistance of human gastric cancer cells by suppressing Wnt/β-catenin signaling.
Yang W, Wu B, Ma N, Wang Y, Guo J, Zhu J, Zhao S. | 12/21/2019 |
| BATF2 gene expression is associated with tuberculosis in the HIV infected patients. | "Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets".
Verma S, Du P, Nakanjako D, Hermans S, Briggs J, Nakiyingi L, Ellner JJ, Manabe YC, Salgame P., Free PMC Article | 06/15/2019 |
| BATF2 gene was modulated after treatment with zebularine and was a poor prognostic marker, since its low levels were correlated with relapse and a poor prognosis for medulloblastoma patients. | The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.
Andrade AF, Borges KS, Suazo VK, Geron L, Corrêa CA, Castro-Gamero AM, de Vasconcelos EJ, de Oliveira RS, Neder L, Yunes JA, Dos Santos Aguiar S, Scrideli CA, Tone LG. | 12/16/2017 |
| Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs and identify BATF2 as a mediator of infection-induced HSPC terminal differentiation | Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.
Matatall KA, Jeong M, Chen S, Sun D, Chen F, Mo Q, Kimmel M, King KY., Free PMC Article | 11/26/2017 |
| Our findings expanded the understanding of the role of BATF2 in tumors, and also suggested a potential of using BATF2 as a therapeutic target to hinder bevacizumab induced epithelial-mesenchymal transition in glioblastoma. | Inhibition of Bevacizumab-induced Epithelial-Mesenchymal Transition by BATF2 Overexpression Involves the Suppression of Wnt/β-Catenin Signaling in Glioblastoma Cells.
Huang W, Zhang C, Cui M, Niu J, Ding W. | 08/19/2017 |
| BATF2 may exert selective pressure on the recombination machinery via a repetitive motif-based mechanism for the maintenance of heterochromatin stability. | Discovery of a Regulatory Motif for Human Satellite DNA Transcription in Response to BATF2 Overexpression.
Bai X, Huang W, Zhang C, Niu J, Ding W. | 11/12/2016 |
| Batf2 has a role in infectious diseases and cancer | Targeting Batf2 for infectious diseases and cancer.
Guler R, Roy S, Suzuki H, Brombacher F., Free PMC Article | 08/20/2016 |
| Results demonstrate that SARI is a novel target gene of glucocorticoid receptor, and the upregulation of SARI plays an important role in dexamethasone's killing effect on B lymphoma cells. | SARI, a novel target gene of glucocorticoid receptor, plays an important role in dexamethasone-mediated killing of B lymphoma cells.
Huang Y, Zhou J, Huang Y, He J, Wang Y, Yang C, Liu D, Zhang L, He F. | 07/16/2016 |
| Suggest that SARI might play an important role in the occurrence and development of prostate cancer. IFN-beta might inhibit the growth of prostate cancer and promote cellular apoptosis by inducing the expression of SARI. | Expression and mechanism of action of the SARI tumor suppressor in prostate cancer.
Chen Q, Gu Y, Liu B., Free PMC Article | 06/28/2016 |
| In conclusion, as a tumor suppressor, BATF2 serves as a prognostic biomarker of esophageal squamous cell carcinoma and it may be a potential therapeutic target for ESCC treatment. | The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma.
Han T, Wang Z, Yang Y, Shu T, Li W, Liu D, Li P, Qi R, Ren Y, Li L, Liu H, Zhang S, Zhang L. | 05/14/2016 |
| these findings indicate that BATF2 status could be served as a potential biomarker to predict prognosis in colorectal cancer | BATF2 in human colorectal cancer.
Liu Z, Yang Y, Zhou X., Free PMC Article | 04/9/2016 |