| Crystal structure of the GTP-binding protein-like domain of AGAP1. | Crystal structure of the GTP-binding protein-like domain of AGAP1.
Cheng N, Zhang H, Zhang S, Ma X, Meng G., Free PMC Article | 11/22/2021 |
| CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma. | CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma.
Lv Q, Wang G, Zhang Y, Shen A, Tang J, Sun Y, Ma C, Wang P., Free PMC Article | 10/23/2021 |
| AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion.
Tsutsumi K, Nakamura Y, Kitagawa Y, Suzuki Y, Shibagaki Y, Hattori S, Ohta Y. | 09/5/2020 |
| 2 Arf GAPs, ASAP1 and AGAP1, have been found to bind directly to and influence the activity of myosins and kinesins, motor proteins associated with filamentous actin and microtubules, respectively. | Arf GAPs and molecular motors.
Luo R, Reed CE, Sload JA, Wordeman L, Randazzo PA, Chen PW., Free PMC Article | 04/11/2020 |
| The effect of AGAP1 Knockdown could be rescued by FLAG-AGAP1, but not by an AGAP1 mutant that did not bind Kif2A efficiently, ArfGAP1-HA or Kif2A-GFP. The results support the hypothesis that the Kif2A.AGAP1 complex contributes to control of cytoskeleton remodeling involved in cell movement. | Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1).
Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA., Free PMC Article | 09/23/2017 |
| GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. | GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
Luo R, Akpan IO, Hayashi R, Sramko M, Barr V, Shiba Y, Randazzo PA., Free PMC Article | 07/28/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | Evaluation of the chromosome 2q37.3 gene CENTG2 as an autism susceptibility gene.
Wassink TH, Piven J, Vieland VJ, Jenkins L, Frantz R, Bartlett CW, Goedken R, Childress D, Spence MA, Smith M, Sheffield VC, Wassink TH, Piven J, Vieland VJ, Jenkins L, Frantz R, Bartlett CW, Goedken R, Childress D, Spence MA, Smith M, Sheffield VC. | 03/13/2008 |
| AGAP1 is unique among the AZAPs in its specificity for Arf1, and this activity is dependent on its NH(2)-terminal GTPase-like domain. AGAP1 induce reciprocal activation of Arf6. | Substrate specificities and activities of AZAP family Arf GAPs in vivo.
Cuthbert EJ, Davis KK, Casanova JE. | 01/21/2010 |
| The AGAP1 has been found to associate with the adaptor protein complex AP-3 and regulate the function of AP-3 endosomes. | The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3.
Nie Z, Fei J, Premont RT, Randazzo PA. | 01/21/2010 |
| overexpression inhibited formation of platelet-derived growth factor-induced ruffles and also induced loss of actin stress fibers | AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton.
Nie Z, Stanley KT, Stauffer S, Jacques KM, Hirsch DS, Takei J, Randazzo PA. | 01/21/2010 |
| AGAP1 is a novel binding partner of nitric oxide-sensitive guanylyl cyclase | AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.
Meurer S, Pioch S, Wagner K, Müller-Esterl W, Gross S. | 01/21/2010 |
| CENTG2 is an intriguing candidate gene that merits further scrutiny for its role in autism. | Evaluation of the chromosome 2q37.3 gene CENTG2 as an autism susceptibility gene.
Wassink TH, Piven J, Vieland VJ, Jenkins L, Frantz R, Bartlett CW, Goedken R, Childress D, Spence MA, Smith M, Sheffield VC, Wassink TH, Piven J, Vieland VJ, Jenkins L, Frantz R, Bartlett CW, Goedken R, Childress D, Spence MA, Smith M, Sheffield VC. | 01/21/2010 |