U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CLIC1 chloride intracellular channel 1 [ Homo sapiens (human) ]

    Gene ID: 1192, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.

    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
    Zheng JH, Zhu YH, Yang J, Ji PX, Zhao RK, Duan ZH, Yao HF, Jia QY, Yin YF, Hu LP, Li Q, Jiang SH, Huo YM, Liu W, Sun YW, Liu DJ.

    08/30/2024
    Chloride Intracellular Channel Protein 1 (CLIC1) Is a Critical Host Cellular Factor for Influenza A Virus Replication.

    Chloride Intracellular Channel Protein 1 (CLIC1) Is a Critical Host Cellular Factor for Influenza A Virus Replication.
    Rashid MU, Coombs KM., Free PMC Article

    02/20/2024
    CLIC1-mediated autophagy confers resistance to DDP in gastric cancer.

    CLIC1-mediated autophagy confers resistance to DDP in gastric cancer.
    Nong ZL, Zhao K, Wang Y, Yu Z, Wang CJ, Chen JQ., Free PMC Article

    12/28/2023
    Comprehensive analysis of clinical prognosis and CLIC1 immune invasion in lung adenocarcinoma.

    Comprehensive analysis of clinical prognosis and CLIC1 immune invasion in lung adenocarcinoma.
    Chen Z, Chen W, Huang R, Chen D, Li Z, Qi X, Sun L, Lin L, Zhang Z., Free PMC Article

    10/8/2022
    CLIC1 promotes the progression of cervical cancer through the PTEN/PI3K/AKT pathway.

    CLIC1 promotes the progression of cervical cancer through the PTEN/PI3K/AKT pathway.
    Qu L, Liu B, Bi X, Liu C, Dong C, Liu W, Dong L.

    07/16/2022
    CLIC1 Drives Angiogenesis in Hepatocellular Carcinoma by Modulating VEGFA.

    CLIC1 Drives Angiogenesis in Hepatocellular Carcinoma by Modulating VEGFA.
    Wei X, Pan B, Yang M, Shu W, Khan AR, Su R, Lin H, Xu X., Free PMC Article

    06/25/2022
    Chloride Intracellular Channel 1 Expression Is Associated With Poor Prognosis of Lung Adenocarcinoma.

    Chloride Intracellular Channel 1 Expression Is Associated With Poor Prognosis of Lung Adenocarcinoma.
    Yasuda Y, Nagano T, Jimbo N, Kiriu T, Suraya R, Hazama D, Yamamoto M, Maniwa Y, Nishimura Y, Kobayashi K.

    01/15/2022
    Identification of chloride intracellular channels as prognostic factors correlated with immune infiltration in hepatocellular carcinoma using bioinformatics analysis.

    Identification of chloride intracellular channels as prognostic factors correlated with immune infiltration in hepatocellular carcinoma using bioinformatics analysis.
    Huang JJ, Lin J, Chen X, Zhu W., Free PMC Article

    12/25/2021
    Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-kappaB.

    Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-κB.
    Wang W, Li X, Xu Y, Guo W, Yu H, Zhang L, Wang Y, Chen X.

    12/18/2021
    PD_BiBIM: Biclustering-based biomarker identification in ESCC microarray data.

    PD_BiBIM: Biclustering-based biomarker identification in ESCC microarray data.
    Patowary P, Bhattacharyya DK.

    12/4/2021
    Exosomal CLIC1 released by CLL promotes HUVECs angiogenesis by regulating ITGbeta1-MAPK/ERK axis.

    Exosomal CLIC1 released by CLL promotes HUVECs angiogenesis by regulating ITGβ1-MAPK/ERK axis.
    Geng HY, Feng ZJ, Zhang JJ, Li GY.

    11/6/2021
    CLIC1 knockout inhibits invasion and migration of gastric cancer by upregulating AMOT-p130 expression.

    CLIC1 knockout inhibits invasion and migration of gastric cancer by upregulating AMOT-p130 expression.
    Qiu Y, Mao YT, Zhu JH, Zhao K, Wang JF, Huang JM, Chang GQ, Guan YT, Huang FY, Hu YJ, Chen JQ, Liu JL.

    09/18/2021
    CLIC1 recruits PIP5K1A/C to induce cell-matrix adhesions for tumor metastasis.

    CLIC1 recruits PIP5K1A/C to induce cell-matrix adhesions for tumor metastasis.
    Peng JM, Lin SH, Yu MC, Hsieh SY., Free PMC Article

    09/11/2021
    Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function.

    Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function.
    Johnston CL, Marzano NR, Paudel BP, Wright G, Benesch JLP, van Oijen AM, Ecroyd H., Free PMC Article

    08/28/2021
    CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.

    CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
    Lu D, Le Y, Ding J, Dou X, Mao W, Zhu J.

    08/21/2021
    A Knock-Down Cell-Based Study for the Functional Analysis of Chloride Intracellular Channel 1 (CLIC1): Integrated Proteomics and Microarray Study.

    A Knock-Down Cell-Based Study for the Functional Analysis of Chloride Intracellular Channel 1 (CLIC1): Integrated Proteomics and Microarray Study.
    Yin SJ, Lee JR, Lee BN, Yang JM, Qian GY, Park YD, Hahn MJ.

    04/3/2021
    Predicting Clinical Dementia Rating Using Blood RNA Levels.

    Predicting Clinical Dementia Rating Using Blood RNA Levels.
    Miller JB, Kauwe JSK., Free PMC Article

    03/13/2021
    CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesis.

    CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesis.
    Uretmen Kagiali ZC, Saner N, Akdag M, Sanal E, Degirmenci BS, Mollaoglu G, Ozlu N., Free PMC Article

    03/13/2021
    Chloride Intracellular Channel Protein 1 (CLIC1), E-cadherin and P-cadherin Define Distinct Subclasses of HER2, Luminal B and Triple-negative Breast Cancer.

    Chloride Intracellular Channel Protein 1 (CLIC1), E-cadherin and P-cadherin Define Distinct Subclasses of HER2, Luminal B and Triple-negative Breast Cancer.
    Raica M, Ceausu AR, Cimpean AM, ComŞa Ş, Sarb S.

    02/6/2021
    Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth.

    Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth.
    Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X., Free PMC Article

    12/26/2020
    CLIC1 Protein Accumulates in Circulating Monocyte Membrane during Neurodegeneration.

    CLIC1 Protein Accumulates in Circulating Monocyte Membrane during Neurodegeneration.
    Carlini V, Verduci I, Cianci F, Cannavale G, Fenoglio C, Galimberti D, Mazzanti M., Free PMC Article

    11/21/2020
    CLIC1 is a key regulator of Ca(2+) signaling in the control of cancer cell survival.

    The inhibition of chloride intracellular channel 1 enhances Ca(2+) and reactive oxygen species signaling in A549 human lung cancer cells.
    Lee JR, Lee JY, Kim HJ, Hahn MJ, Kang JS, Cho H., Free PMC Article

    06/27/2020
    LncRNA-UCA1 promoted the metastasis of Bile duct carcinoma cells by regulating the expression of miR-122 and its downstream gene mRNA CLIC1 and promoted the activation of the ERK/MAPK pathway, which expanded the horizons of targeted therapy of cholangiocarcinoma.

    Upregulated lncRNA-UCA1 contributes to metastasis of bile duct carcinoma through regulation of miR-122/CLIC1 and activation of the ERK/MAPK signaling pathway.
    Kong L, Wu Q, Zhao L, Ye J, Li N, Yang H., Free PMC Article

    06/13/2020
    findings uncover the identification of a GXXXG motif in CLIC1, which likely serves as the cholesterol-binding domain, that facilitates the protein's membrane interaction and insertion

    A conserved GXXXG motif in the transmembrane domain of CLIC proteins is essential for their cholesterol-dependant membrane interaction.
    Hossain KR, Turkewitz DR, Holt SA, Herson L, Brown LJ, Cornell BA, Curmi PMG, Valenzuela SM.

    04/4/2020
    Cellular CLIC1 and CLIC4 are required for efficient Chikungunya virus replication.

    Chikungunya virus requires cellular chloride channels for efficient genome replication.
    Müller M, Slivinski N, Todd EJAA, Khalid H, Li R, Karwatka M, Merits A, Mankouri J, Tuplin A., Free PMC Article

    02/1/2020
    firstprevious page of 4 nextlast