| CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation. | CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation.
Wang Z, Xu H, Chen M, Lu Y, Zheng L, Ma L., Free PMC Article | 08/17/2023 |
| CD193 (CCR3) expression by B cells correlates with reduced IgE production in paediatric schistosomiasis. | CD193 (CCR3) expression by B cells correlates with reduced IgE production in paediatric schistosomiasis.
Onkanga IO, Sang H, Hamilton R, Ondigo BN, Jaoko W, Odiere MR, Ganley-Leal L. | 05/1/2023 |
| CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines. | CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines.
Kaibori Y, Nagakubo D. | 01/21/2023 |
| The rs13075270 and rs13092160 polymorphisms of CCR1 and CCR3 genes on oral aphthous-like lesions in PFAPA syndrome. | The rs13075270 and rs13092160 polymorphisms of CCR1 and CCR3 genes on oral aphthous-like lesions in PFAPA syndrome.
Li W, Li N, Yang G, Li Y. | 07/16/2022 |
| CCR3 gene overexpression in patients with Down syndrome. | CCR3 gene overexpression in patients with Down syndrome.
Salemi M, Cannarella R, Marchese G, Salluzzo MG, Ravo M, Barone C, Cordella A, Caniglia S, Castiglione R, Ragalmuto A, Calogero AE, Romano C. | 01/22/2022 |
| Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3. | Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3.
Shah SA, Kanabar V, Riffo-Vasquez Y, Mohamed Z, Cleary SJ, Corrigan C, James AL, Elliot JG, Shute JK, Page CP, Pitchford SC., Free PMC Article | 07/31/2021 |
| Stromal CCL5 Promotes Breast Cancer Progression by Interacting with CCR3 in Tumor Cells. | Stromal CCL5 Promotes Breast Cancer Progression by Interacting with CCR3 in Tumor Cells.
Yamaguchi M, Takagi K, Narita K, Miki Y, Onodera Y, Miyashita M, Sasano H, Suzuki T., Free PMC Article | 04/24/2021 |
| The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes. | The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes.
Guérard A, Laurent V, Fromont G, Estève D, Gilhodes J, Bonnelye E, Le Gonidec S, Valet P, Malavaud B, Reina N, Attané C, Muller C., Free PMC Article | 04/17/2021 |
| KSHV enhances mesenchymal stem cell homing and promotes KS-like pathogenesis. | KSHV enhances mesenchymal stem cell homing and promotes KS-like pathogenesis.
Wang X, Chen W, Yuan Y. | 02/27/2021 |
| [Effect of CCR3 gene on related inflammatory cells in respiratory allergic diseases]. | [Effect of CCR3 gene on related inflammatory cells in respiratory allergic diseases].
Tang S, Shu X., Free PMC Article | 02/13/2021 |
| Analysis of CCR3 expression in corneal neovascularization in a murine model and human corneas. | Analysis of CCR3 expression in corneal neovascularization in a murine model and human corneas.
Haber A, Polania-Baron EJ, Bolaños-Jimenez R, Navas A, Graue Hernandez EO, Garfias Y. | 01/16/2021 |
| Mycosis fungoides/Sezary syndrome patients with high CCR3 or CCR4 expression had a poor survival prognosis. | Expression of CCR3 and CCR4 Suggests a Poor Prognosis in Mycosis Fungoides and Sézary Syndrome.
Shono Y, Suga H, Kamijo H, Fujii H, Oka T, Miyagaki T, Shishido-Takahashi N, Sugaya M, Sato S. | 02/1/2020 |
| Sequential activation of CCR3 and then PGD2 receptors by autocrine ligands in response to leptin stimulation of eosinophils culminates with eosinophil activation, characterized by assembly of lipidic cytoplasmic platforms synthesis and secretion of the pleiotropic lipid mediators, PGD2, and LTC4. Study results suggested involvement of H-PGDS, rather than L-PGDS, in leptin-induced synthesis of PGD2 by eosinophils. | Leptin Elicits LTC(4) Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD(2) Receptors.
Amorim NRT, Luna-Gomes T, Gama-Almeida M, Souza-Almeida G, Canetti C, Diaz BL, Weller PF, Torres Bozza P, Maya-Monteiro CM, Bandeira-Melo C., Free PMC Article | 10/26/2019 |
| MACs from Familial hypercholesterolemia (FH)-MACs have an inflammatory phenotype that is characterized by the up-regulation of CCR3, CCR4, and CXCR1 under the control of miR-505-3p. These results suggest a chronic inflammatory condition in FH innate immunity cells that is not reverted by standard lipid-lowering treatment | miR-505-3p controls chemokine receptor up-regulation in macrophages: role in familial hypercholesterolemia.
Escate R, Mata P, Cepeda JM, Padró T, Badimon L. | 10/27/2018 |
| CCR3 exists as a mixture of monomers and dimers under nearly physiological conditions. The monomeric CCR3 receptor is the minimal functional unit in cellular signal transduction. Agonists increase dimers and oligomers at high concentrations. Antagonists do not affect oligomeric status. Monomeric CCR3 exhibits a stronger chemotactic response in the migration assay of stably transfected CCR3 cells. | Regulation of the Oligomeric Status of CCR3 with Binding Ligands Revealed by Single-Molecule Fluorescence Imaging.
Song Y, Ge B, Lao J, Wang Z, Yang B, Wang X, He H, Li J, Huang F. | 06/2/2018 |
| Study shows that CCR3, receptor of CCL28, was highly expressed in vascular endothelial cells in lung adenocarcinoma and is targeted by CCL28 to regulate angiogenesis. | Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells.
Huang G, Tao L, Shen S, Chen L., Free PMC Article | 04/28/2018 |
| Findings suggest that CCL11-CCR3 binding is involved in the progression of GBM. | Expression and prognostic significance of CCL11/CCR3 in glioblastoma.
Tian M, Chen L, Ma L, Wang D, Shao B, Wu J, Wu H, Jin Y., Free PMC Article | 01/27/2018 |
| Data show that high mRNA expression of CCR3 was related with improved relapse-free survival in luminal-A/B. | Intratumoral expression of CCR3 in breast cancer is associated with improved relapse-free survival in luminal-like disease.
Gong DH, Fan L, Chen HY, Ding KF, Yu KD., Free PMC Article | 12/16/2017 |
| the expression of CCR3 on dispersed synovial tissue and peripheral blood cells in rheumatoid arthritis, was investigated. | Upregulated expression of CCR3 in rheumatoid arthritis and CCR3-dependent activation of fibroblast-like synoviocytes.
Liu X, Zhang H, Chang X, Shen J, Zheng W, Xu Y, Wang J, Gao W, He S. | 09/30/2017 |
| Chemokine receptors CCR3 and CCR4, and the mucosa specific chemokine CCL28 have predominant roles in oral wound healing by increasing human gingiva fibroblast proliferation, migration, and the secretion of IL-6 and HGF and reducing the secretion of TIMP-1. | Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Buskermolen JK, Roffel S, Gibbs S., Free PMC Article | 09/23/2017 |
| simvastatin was demonstrated to inhibit IL-5-induced CCR3 expression and chemotaxis of eosinophils mediated via the mevalonate pathway. | Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils.
Fu CH, Tsai WC, Lee TJ, Huang CC, Chang PH, Su Pang JH., Free PMC Article | 07/15/2017 |
| Data indicate that approximately 4.5% dispersed osteoarthritis (OA) synovial tissue cells are CC chemokine receptor CCR 3 (CCR3)+ cells. | Upregulated expression of CCR3 in osteoarthritis and CCR3 mediated activation of fibroblast-like synoviocytes.
Chang X, Shen J, Yang H, Xu Y, Gao W, Wang J, Zhang H, He S. | 09/17/2016 |
| This meta-analysis provides robust estimates that interleukin 18 receptor accessory protein rs917997 and chemokine (C-C motif) receptor 3 rs6441961 are potential risk factors for celiac disease in European populations. | Systematic review and meta-analysis of the association between IL18RAP rs917997 and CCR3 rs6441961 polymorphisms with celiac disease risks.
Yang G, Zhang B, Huang W, Zhang N, Dong F, Jing L, Wang M, Liu Y, Guo C, Pan H, Wei X, Jing C. | 06/28/2016 |
| Results highlight the potential role of CCR genes in narcolepsy and support the hypothesis that patients with narcolepsy have impaired immune function. | A polymorphism in CCR1/CCR3 is associated with narcolepsy.
Toyoda H, Miyagawa T, Koike A, Kanbayashi T, Imanishi A, Sagawa Y, Kotorii N, Kotorii T, Hashizume Y, Ogi K, Hiejima H, Kamei Y, Hida A, Miyamoto M, Imai M, Fujimura Y, Tamura Y, Ikegami A, Wada Y, Moriya S, Furuya H, Takeuchi M, Kirino Y, Meguro A, Remmers EF, Kawamura Y, Otowa T, Miyashita A, Kashiwase K, Khor SS, Yamasaki M, Kuwano R, Sasaki T, Ishigooka J, Kuroda K, Kume K, Chiba S, Yamada N, Okawa M, Hirata K, Mizuki N, Uchimura N, Shimizu T, Inoue Y, Honda Y, Mishima K, Honda M, Tokunaga K. | 06/11/2016 |
| Periprostatic adipocytes drive prostate cancer progression in obesity via CCL7 secretion which stimulates CCR3 expressing tumor cells. | Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity.
Laurent V, Guérard A, Mazerolles C, Le Gonidec S, Toulet A, Nieto L, Zaidi F, Majed B, Garandeau D, Socrier Y, Golzio M, Cadoudal T, Chaoui K, Dray C, Monsarrat B, Schiltz O, Wang YY, Couderc B, Valet P, Malavaud B, Muller C., Free PMC Article | 05/21/2016 |