Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY., Free PMC Article

Loss of Cdc42 in Exocrine Acini Decreases Saliva Secretion but Increases Tear Secretion-A Potential Model of Exocrine Gland Senescence.
Nagase H, Shitara A, Ohno Y, Satoh K, Kashimata M., Free PMC Article

ROBO1 deficiency impairs HSPC homeostasis and erythropoiesis via CDC42 and predicts poor prognosis in MDS.
Jin JC, Chen BY, Deng CH, Chen JN, Xu F, Tao Y, Hu CL, Xu CH, Chang BH, Wang Y, Fei MY, Liu P, Yu PC, Li ZJ, Li XY, Chen SB, Jiang YL, Chen XC, Zong LJ, Zhang JY, Ren YY, Xu FH, Liu Q, Huang XH, Guo J, He Q, Song LX, Zhou LY, Su JY, Xiao C, Zhang YM, Yan M, Zhang Z, Wu D, Chang CK, Li X, Wang L, Wu LY.

Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.
Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Antón J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L, Boztug K.

Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.
Jiang S, Xu CM, Yao S, Zhang R, Li XZ, Zhang RZ, Xie TY, Xing YQ, Zhang Q, Zhou XJ, Liao L, Dong JJ., Free PMC Article

Cdc42 promotes thyroid cancer cell proliferation and migration and tumor-associated macrophage polarization through the PTEN/AKT pathway.
Huang D, Qiu H, Miao L, Guo L, Zhang X, Lin M, Li Z, Li F.

Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription.
Wirth A, Labus J, Abdel Galil D, Schill Y, Schmidt S, Bunke T, Gorinski N, Yokoi N, Fukata M, Ponimaskin E., Free PMC Article

CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling.
Zhang Z, Zhang F, Davis AK, Xin M, Walz G, Tian W, Zheng Y., Free PMC Article

Cdc42 is required for male germline niche development in mice.
Mori Y, Takashima S, Kanatsu-Shinohara M, Yi Z, Shinohara T.

Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis.
Heinrich A, Bhandary B, Potter SJ, Ratner N, DeFalco T., Free PMC Article

Inhibition of CDC42 reduces macrophage recruitment and suppresses lung tumorigenesis in vivo.
Zhang B, Zhang J, Xia L, Luo J, Zhang L, Xu Y, Zhu X, Chen G.

Cdc42 has important roles in postnatal angiogenesis and vasculature formation.
Yoshida Y, Yamada A, Akimoto Y, Abe K, Matsubara S, Hayakawa J, Tanaka J, Kinoshita M, Kato T, Ogata H, Sakashita A, Mishima K, Kubota Y, Kawakami H, Kamijo R, Iijima T.

CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42.
Liu D, Tian X, Liu Y, Song H, Cheng X, Zhang X, Yan C, Han Y., Free PMC Article

Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver.
Zhou Y, Ji H, Xu Q, Zhang X, Cao X, Chen Y, Shao M, Wu Z, Zhang J, Lu C, Yang J, Shi Y, Bu H., Free PMC Article

Cdc42 localized in the CatSper signaling complex regulates cAMP-dependent pathways in mouse sperm.
Luque GM, Xu X, Romarowski A, Gervasi MG, Orta G, De la Vega-Beltrán JL, Stival C, Gilio N, Dalotto-Moreno T, Krapf D, Visconti PE, Krapf D, Darszon A, Buffone MG.

The Small GTPase Cdc42 Negatively Regulates the Formation of Neutrophil Extracellular Traps by Engaging Mitochondria.
Tackenberg H, Möller S, Filippi MD, Laskay T., Free PMC Article

Specific deletion of CDC42 in pancreatic β cells attenuates glucose-induced insulin expression and secretion in mice.
He XQ, Wang N, Zhao JJ, Wang D, Wang CJ, Xie L, Zheng HY, Shi SZ, He J, Zhou J, Xin HB, Deng KY.

The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway.
Lee YD, Kim B, Jung S, Kim H, Kim MK, Kwon JO, Song MK, Lee ZH, Kim HH., Free PMC Article

Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration.
Zhang X, Bandyopadhyay S, Araujo LP, Tong K, Flores J, Laubitz D, Zhao Y, Yap G, Wang J, Zou Q, Ferraris R, Zhang L, Hu W, Bonder EM, Kiela PR, Coffey R, Verzi MP, Ivanov II, Gao N., Free PMC Article

Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development.
Ma Y, Jing J, Feng J, Yuan Y, Wen Q, Han X, He J, Chen S, Ho TV, Chai Y., Free PMC Article

The Small GTPase Cdc42 Is a Major Regulator of Neutrophil Effector Functions.
Tackenberg H, Möller S, Filippi MD, Laskay T., Free PMC Article

Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42.
Gu J, Yang Z, Yuan L, Guo S, Wang D, Zhao N, Meng L, Liu H, Chen W, Ma J.

Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ(42) in triggering receptor expressed on myeloid cells 2 loss-of-function murine models.
Rong Z, Cheng B, Zhong L, Ye X, Li X, Jia L, Li Y, Shue F, Wang N, Cheng Y, Huang X, Liu CC, Fryer JD, Wang X, Zhang YW, Zheng H.

Neuropathophysiological significance of the c.1449T>C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome.
Hamada N, Ito H, Shibukawa Y, Morishita R, Iwamoto I, Okamoto N, Nagata KI.

miR-485-5p suppresses Schwann cell proliferation and myelination by targeting cdc42 and Rac1.
Zhang Z, Li X, Li A, Wu G.