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    CPT1A carnitine palmitoyltransferase 1A [ Homo sapiens (human) ]

    Gene ID: 1374, updated on 4-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.

    Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.
    Praveen Z, Choi SW, Lee JH, Park JY, Oh HJ, Kwon IJ, Park JH, Kim MK., Free PMC Article

    11/4/2024
    CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.

    CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
    Wu Y, Huang J, Liu L, Zhang X, Zhang W, Li Q.

    07/25/2024
    CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.

    CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.
    Liu Y, Wang F, Yan G, Tong Y, Guo W, Li S, Qian Y, Li Q, Shu Y, Zhang L, Zhang Y, Xia Q.

    06/28/2024
    Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase-1A-induced lipid metabolism in diabetic nephropathy.

    Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase-1A-induced lipid metabolism in diabetic nephropathy.
    Zhang Y, Zhang Z, Huang L, Wang C, Yang P, Zhang L, Liao X.

    06/18/2024
    CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells.

    CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells.
    Liu S, Chen X, Zhang L, Lu B., Free PMC Article

    03/19/2024
    Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.

    Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.
    Sarnowski C, Huan T, Ma Y, Joehanes R, Beiser A, DeCarli CS, Heard-Costa NL, Levy D, Lin H, Liu CT, Liu C, Meigs JB, Satizabal CL, Florez JC, Hivert MF, Dupuis J, De Jager PL, Bennett DA, Seshadri S, Morrison AC., Free PMC Article

    11/1/2023
    CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing.

    CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing.
    Liu Z, Liu W, Wang W, Ma Y, Wang Y, Drum DL, Cai J, Blevins H, Lee E, Shah S, Fisher PB, Wang X, Fang X, Guo C, Wang XY., Free PMC Article

    09/28/2023
    DNA Methylation Near CPT1A and Changes in Triglyceride-rich Lipoproteins in Response to Weight-loss Diet Interventions.

    DNA Methylation Near CPT1A and Changes in Triglyceride-rich Lipoproteins in Response to Weight-loss Diet Interventions.
    Li X, Shao X, Xue Q, Kou M, Champagne CM, Koseva BS, Heianza Y, Grundberg E, Bazzano LA, Bray GA, Sacks FM, Qi L., Free PMC Article

    07/21/2023
    NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation.

    NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation.
    Xu R, Liu Y, Ma L, Sun Y, Liu H, Yang Y, Jin T, Yang D., Free PMC Article

    06/26/2023
    Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer.

    Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer.
    Zhu Y, Wang Y, Li Y, Li Z, Kong W, Zhao X, Chen S, Yan L, Wang L, Tong Y, Shao H., Free PMC Article

    06/21/2023
    CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.

    CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
    Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H.

    02/26/2023
    The impact of variance in carnitine palmitoyltransferase-1 expression on breast cancer prognosis is stratified by clinical and anthropometric factors.

    The impact of variance in carnitine palmitoyltransferase-1 expression on breast cancer prognosis is stratified by clinical and anthropometric factors.
    Liu R, Ospanova S, Perry RJ., Free PMC Article

    02/10/2023
    Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres.

    Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres.
    Kim SJ, Park SJ, Park J, Cho HJ, Shim JK, Seon J, Choi RJ, Yoon SJ, Moon JH, Kim EH, Seo EK, Kim SH, Kim HS, Teo WY, Chang JH, Yook JI, Kang SG.

    01/14/2023
    Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid beta-oxidation.

    Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation.
    Pham L, Komalavilas P, Eddie AM, Thayer TE, Greenwood DL, Liu KH, Weinberg J, Patterson A, Fessel JP, Boyd KL, Schafer JC, Kuck JL, Shaver AC, Flaherty DK, Matlock BK, Wijers CDM, Serezani CH, Jones DP, Brittain EL, Rathmell JC, Noto MJ., Free PMC Article

    12/24/2022
    CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis.

    CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis.
    Tian T, Lu Y, Lin J, Chen M, Qiu H, Zhu W, Sun H, Huang J, Yang H, Deng W., Free PMC Article

    12/17/2022
    Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis.

    Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis.
    Bernard JN, Chinnaiyan V, Andl T, Le Bras GF, Qureshi MN, Altomare DA, Andl CD., Free PMC Article

    10/22/2022
    The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach.

    The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach.
    Das M, Giannoudis A, Sharma V., Free PMC Article

    10/8/2022
    Contribution of Adiponectin/Carnitine Palmityl Transferase 1A-Mediated Fatty Acid Metabolism during the Development of Idiopathic Pulmonary Fibrosis.

    Contribution of Adiponectin/Carnitine Palmityl Transferase 1A-Mediated Fatty Acid Metabolism during the Development of Idiopathic Pulmonary Fibrosis.
    Wu W, Zhang G, Qiu L, Liu X, Zhou S, Wu J., Free PMC Article

    09/3/2022
    Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells.

    Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells.
    Luo M, Liu YQ, Zhang H, Luo CH, Liu Q, Wang WY, He ZC, Chen C, Zhang XN, Mao M, Yang KD, Wang C, Chen XQ, Fu WJ, Niu Q, Bian XW, Shi Y, Ping YF.

    07/9/2022
    CPT1A-Mediated Fatty Acid Oxidation Promotes Precursor Osteoclast Fusion in Rheumatoid Arthritis.

    CPT1A-Mediated Fatty Acid Oxidation Promotes Precursor Osteoclast Fusion in Rheumatoid Arthritis.
    Huang Z, Luo R, Yang L, Chen H, Zhang X, Han J, Wang H, Zhou Z, Wang Z, Shao L., Free PMC Article

    05/14/2022
    Fatty acid beta-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway.

    Fatty acid β-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway.
    Zeng F, Yao M, Wang Y, Zheng W, Liu S, Hou Z, Cheng X, Sun S, Li T, Zhao H, Luo Y, Li J., Free PMC Article

    04/23/2022
    Overexpression CPT1A reduces lipid accumulation via PPARalpha/CD36 axis to suppress the cell proliferation in ccRCC.

    Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC.
    Yang H, Zhao H, Ren Z, Yi X, Zhang Q, Yang Z, Kuang Y, Zhu Y., Free PMC Article

    04/2/2022
    Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids.

    Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids.
    Horibata Y, Sugimoto H., Free PMC Article

    03/26/2022
    Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.

    Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.
    Huang D, Chowdhury S, Wang H, Savage SR, Ivey RG, Kennedy JJ, Whiteaker JR, Lin C, Hou X, Oberg AL, Larson MC, Eskandari N, Delisi DA, Gentile S, Huntoon CJ, Voytovich UJ, Shire ZJ, Yu Q, Gygi SP, Hoofnagle AN, Herbert ZT, Lorentzen TD, Calinawan A, Karnitz LM, Weroha SJ, Kaufmann SH, Zhang B, Wang P, Birrer MJ, Paulovich AG., Free PMC Article

    03/5/2022
    Association of CPT1A gene polymorphism with the risk of gestational diabetes mellitus: a case-control study.

    Association of CPT1A gene polymorphism with the risk of gestational diabetes mellitus: a case-control study.
    Ren Q, Guo M, Yang F, Han T, Du W, Zhao F, Li J, Li W, Feng Y, Wang S, Zhang Y, Wu W., Free PMC Article

    01/1/2022
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