| Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer. | Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer.
Sakata K, Kanda M, Shimizu D, Nakamura S, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Kodera Y., Free PMC Article | 04/30/2022 |
| CRABP1 and CRABP2 Protein Levels Correlate with Each Other but Do Not Correlate with Sensitivity of Breast Cancer Cells to Retinoic Acid. | CRABP1 and CRABP2 Protein Levels Correlate with Each Other but Do Not Correlate with Sensitivity of Breast Cancer Cells to Retinoic Acid.
Enikeev AD, Komelkov AV, Axelrod ME, Galetsky SA, Kuzmichev SA, Tchevkina EM. | 07/3/2021 |
| Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases. | Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases.
Lin YL, Lin YW, Nhieu J, Zhang X, Wei LN., Free PMC Article | 03/27/2021 |
| Cellular Retinoic-Acid Binding Protein 2 in Solid Tumor. | Cellular Retinoic-Acid Binding Protein 2 in Solid Tumor.
Jiao X, Liu R, Huang J, Lu L, Li Z, Xu L, Li E. | 01/9/2021 |
| Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance. | Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance.
Bang BR, Li M, Tsai KN, Aoyagi H, Lee SA, Machida K, Aizaki H, Jung JU, Ou JJ, Saito T., Free PMC Article | 02/1/2020 |
| These are supported by the fact that CRABP1 gene knockout (KO) mice exhibit multiple phenotypes including hippocampal NSC expansion and spontaneous cardiac hypertrophy. This indicates that more potential processes/signaling pathways involving atRA-CRABP1 may exist, which remain to be identified. | All-trans Retinoic Acid as a Versatile Cytosolic Signal Modulator Mediated by CRABP1.
Nagpal I, Wei LN., Free PMC Article | 12/28/2019 |
| We conclude that the underexpression of CRABP1 and the overexpression of LCN2 may be useful diagnostic biomarkers in thyroid tumours with questionable malignity, and the overexpression of LCN2 and C1QL1 may be useful for prognostic purposes. | CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension.
Celestino R, Nome T, Pestana A, Hoff AM, Gonçalves AP, Pereira L, Cavadas B, Eloy C, Bjøro T, Sobrinho-Simões M, Skotheim RI, Soares P., Free PMC Article | 08/18/2018 |
| Holo-CRABPs had higher affinity for CYP26B1 than free atRA, but both apo-CRABPs(CRABP-I and CRABP-II ) inhibited the formation of 4-OH-RA by CYP26B1. | Direct protein-protein interactions and substrate channeling between cellular retinoic acid binding proteins and CYP26B1.
Nelson CH, Peng CC, Lutz JD, Yeung CK, Zelter A, Isoherranen N., Free PMC Article | 05/13/2017 |
| p75NTR and CRABP1 modulate the effect of fenretinide on neuroblastoma cells | Cell Line-Dependent Variability of Coordinate Expression of p75NTR and CRABP1 and Modulation of Effects of Fenretinide on Neuroblastoma Cells.
Yang YP, Wang S, Li X, Schor NF., Free PMC Article | 12/17/2016 |
| miR-93/miR-106b/miR-375-CIC-CRABP1 is a novel key regulatory axis in prostate cancer progression | miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression.
Choi N, Park J, Lee JS, Yoe J, Park GY, Kim E, Jeon H, Cho YM, Roh TY, Lee Y., Free PMC Article | 08/13/2016 |
| CRABP1 expression is maintained in ER- and triple-negative breast tumors, and that elevated levels of CRABP1 is a significant indicator of high tumor grade, Ki67 immunoreactivity, and poor prognosis. | CRABP1 is associated with a poor prognosis in breast cancer: adding to the complexity of breast cancer cell response to retinoic acid.
Liu RZ, Garcia E, Glubrecht DD, Poon HY, Mackey JR, Godbout R., Free PMC Article | 03/26/2016 |
| the first evidence of pro-tumorigenic and pro-metastatic activity of CRABP1 in mesenchymal and neuroendocrine tumors. | CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors.
Kainov Y, Favorskaya I, Delektorskaya V, Chemeris G, Komelkov A, Zhuravskaya A, Trukhanova L, Zueva E, Tavitian B, Dyakova N, Zborovskaya I, Tchevkina E., Free PMC Article | 03/5/2016 |
| we demonstrated significant changes in CRABP1 and CRABP2 expression in non-small cell lung cancer samples | Expression and clinical significance of CRABP1 and CRABP2 in non-small cell lung cancer.
Favorskaya I, Kainov Y, Chemeris G, Komelkov A, Zborovskaya I, Tchevkina E. | 01/10/2015 |
| Factors involved in the retinoid pathway, in particular upregulation of CRBP, CRABP1 and CRABP2, also showed differential expression in tumors with different histological subtypes | Proteome analysis of the effects of all-trans retinoic acid on human germ cell tumor cell lines.
Honecker F, Rohlfing T, Harder S, Braig M, Gillis AJ, Glaesener S, Barett C, Bokemeyer C, Buck F, Brümmendorf TH, Looijenga LH, Balabanov S. | 09/20/2014 |
| Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. | Expression of CRABP1, GRP, and RERG mRNA in clinically non-functioning and functioning pituitary adenomas.
Chile T, Corrêa-Giannella ML, Fortes MA, Bronstein MD, Cunha-Neto MB, Giannella-Neto D, Giorgi RR. | 05/5/2012 |
| reduced expression of CRABP1 has a potential as a prognostic marker for serous adenocarcinoma which is the most frequent histological ovarian tumor type and also for clear cell carcinoma that often exhibits chemo-resistance. | CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma.
Miyake T, Ueda Y, Matsuzaki S, Miyatake T, Yoshino K, Fujita M, Nomura T, Enomoto T, Kimura T. | 05/21/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesMaternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC. Polymorphisms in TGFB1 and PDGFRB are associated with Moyamoya disease in European patients.
Roder C, Peters V, Kasuya H, Nishizawa T, Takehara Y, Berg D, Schulte C, Khan N, Tatagiba M, Krischek B. | 09/15/2010 |
| The authors identified several dysregulated genes and proteins, but only the cellular retinoic acid binding protein 1 (CRABP1) was up-regulated exclusively in cells expressing an increased Abeta42/Abeta40 ratio. | Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces their differentiation potential.
Uhrig M, Brechlin P, Jahn O, Knyazev Y, Weninger A, Busia L, Honarnejad K, Otto M, Hartmann T., Free PMC Article | 01/21/2010 |
| Decreases in the CRABP1 (cellular retinoic acid binding protein 1) and TFF3 (trefoil factor 3) expression levels identified these as candidate molecular biomarkers for papillary thyroid carcinoma. | TIMP1 and SERPIN-A overexpression and TFF3 and CRABP1 underexpression as biomarkers for papillary thyroid carcinoma.
Hawthorn L, Stein L, Varma R, Wiseman S, Loree T, Tan D. | 01/21/2010 |
| As epidermal basal keratinocyte proliferation is stimulated by paracrine growth factors secreted by ATRA activated suprabasal keratinocytes, our results indicate that CRABPI overexpression in suprabasal keratinocytes enhances ATRA. | Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid.
Tang XH, Vivero M, Gudas LJ. | 01/21/2010 |
| supports an active role for PLZF and RARalpha-PLZF in leukemogenesis, identifies up-regulation of CRABPI | RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.
Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade D., Free PMC Article | 01/21/2010 |
| Frequent methylation-associated silencing of CRABP1 is associated with esophageal squamous-cell carcinoma | Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.
Tanaka K, Imoto I, Inoue J, Kozaki K, Tsuda H, Shimada Y, Aiko S, Yoshizumi Y, Iwai T, Kawano T, Inazawa J. | 01/21/2010 |
| DNA hypermethylation of tumour suppressor genes seems to play an important role in ovarian carcinogenesis and HOXA9, HOXB5, SCGB3A1, and CRABP1 are identified as novel hypermethylated target genes in this tumour type | DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets.
Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE., Free PMC Article | 01/21/2010 |
| increased CYP26-mediated catabolism of retinoic by CRABP-I transfection might decrease the amount of retinoic acid that is accessible to the nuclear receptors | The effect of cellular retinoic acid binding protein-I expression on the CYP26-mediated catabolism of all-trans retinoic acid and cell proliferation in head and neck squamous cell carcinoma.
Won JY, Nam EC, Yoo SJ, Kwon HJ, Um SJ, Han HS, Kim SH, Byun Y, Kim SY. | 01/21/2010 |
| Loss of cellular retinoic acid binding protein 1 function due to hypermethylation of its promoter leads to pathogenesis of papillary thyroid carcinoma | Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.
Huang Y, de la Chapelle A, Pellegata NS. | 01/21/2010 |