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    CREB1 cAMP responsive element binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 1385, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CREB activates the MafA promoter through proximal E-boxes and a CCAAT motif in pancreatic beta-cells.

    CREB activates the MafA promoter through proximal E-boxes and a CCAAT motif in pancreatic β-cells.
    Aida Y, Kataoka K.

    10/7/2024
    Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic Subunit Beta Activation.

    Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic Subunit Beta Activation.
    Pei W, Yin W, Yu T, Zhang X, Zhang Q, Yang X, Shi C, Shen W, Liu G.

    10/3/2024
    CREB1 promotes expression of immune checkpoint HLA-E leading to immune escape in multiple myeloma.

    CREB1 promotes expression of immune checkpoint HLA-E leading to immune escape in multiple myeloma.
    Ismael A, Robinette AJ, Huric L, Schuetz J, Dona K, Benson D, Cocucci E, Cottini F., Free PMC Article

    09/6/2024
    Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.

    Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
    Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R.

    09/3/2024
    Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.

    Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.
    Watson MJ, Berger PL, Banerjee K, Frank SB, Tang L, Ganguly SS, Hostetter G, Winn M, Miranti CK., Free PMC Article

    08/8/2024
    Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis.

    Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis.
    He C, Zeng Z, Yang Y, Ye S, Wu Q, Liu X, Liu C, Zeng W, Liu S.

    07/22/2024
    Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.

    Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.
    Cai Y, Zhou Y, Yang Q, Xu J, Da Q, Ma Q, Zhao D, Lu T, Kim HW, Fulton D, Jiang X, Weintraub NL, Dong K, Xu S, Hong M, Liu Z, Huo Y.

    05/23/2024
    The CREB1/WNK1 axis promotes the tumorigenesis of ovarian cancer via regulating HIF-1.

    The CREB1/WNK1 axis promotes the tumorigenesis of ovarian cancer via regulating HIF-1.
    Ma Y, Zong H, Pan P, Shang H, Yang X.

    05/10/2024
    The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.

    The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
    Zheng T, Shen B, Bai Y, Li E, Zhang X, Hu Y, Gao T, Dong Q, Zhu L, Jin R, Shi H, Liu H, Gao Y, Liu X, Cao C., Free PMC Article

    05/3/2024
    [MiR-26-3p regulates proliferation, migration, invasion and apoptosis of glioma cells by targeting CREB1].

    [MiR-26-3p regulates proliferation, migration, invasion and apoptosis of glioma cells by targeting CREB1].
    Huang Q, Zhou J, Wang Z, Yang K, Chen Z., Free PMC Article

    04/24/2024
    Suppression of KLF5 basal expression in oral carcinoma-derived cells through three intact CREB1-binding sites in the silencer region.

    Suppression of KLF5 basal expression in oral carcinoma-derived cells through three intact CREB1-binding sites in the silencer region.
    Katsuumi R, Negishi T, Imai K, Mihara N.

    03/8/2024
    PIN1P1 is activated by CREB1 and promotes gastric cancer progression via interacting with YBX1 and upregulating PIN1.

    PIN1P1 is activated by CREB1 and promotes gastric cancer progression via interacting with YBX1 and upregulating PIN1.
    Wang YW, Zhu WJ, Ma RR, Tian YR, Chen X, Gao P., Free PMC Article

    01/30/2024
    CREB: A multifaceted transcriptional regulator of neural and immune function in CNS tumors.

    CREB: A multifaceted transcriptional regulator of neural and immune function in CNS tumors.
    Dinevska M, Widodo SS, Cook L, Stylli SS, Ramsay RG, Mantamadiotis T.

    01/26/2024
    CREB1 Facilitates GABAergic Neural Differentiation of Human Mesenchymal Stem Cells through BRN2 for Pain Alleviation and Locomotion Recovery after Spinal Cord Injury.

    CREB1 Facilitates GABAergic Neural Differentiation of Human Mesenchymal Stem Cells through BRN2 for Pain Alleviation and Locomotion Recovery after Spinal Cord Injury.
    Kao Y, Zhu H, Yang Y, Shen W, Song W, Zhang R, Liu Y, Liu H, Kong X., Free PMC Article

    01/16/2024
    CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate.

    CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate.
    Bal G, Schneikert J, Li Z, Franke K, Tripathi SR, Zuberbier T, Babina M., Free PMC Article

    01/16/2024
    Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization.

    Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization.
    Zhou P, Ouyang L, Jiang T, Tian Y, Deng W, Wang H, Kong S, Lu Z.

    01/9/2024
    LncRNA TDRKH-AS1 promotes breast cancer progression via the miR-134-5p/CREB1 axis.

    LncRNA TDRKH-AS1 promotes breast cancer progression via the miR-134-5p/CREB1 axis.
    Ding Y, Huang Y, Zhang F, Gong L, Liang C, Ding K, He X, Ding X, Chen Y., Free PMC Article

    11/30/2023
    LINC02454 promotes thyroid carcinoma progression via upregulating HMGA2 through CREB1.

    LINC02454 promotes thyroid carcinoma progression via upregulating HMGA2 through CREB1.
    Cao Y, Li J, Du Y, Sun Y, Liu L, Fang H, Liang Y, Mao S.

    11/28/2023
    CREB1 alleviates the apoptosis and potentiates the osteogenic differentiation of zoledronic acid-treated human periodontal ligament stem cells via up-regulating VEGF.

    CREB1 alleviates the apoptosis and potentiates the osteogenic differentiation of zoledronic acid-treated human periodontal ligament stem cells via up-regulating VEGF.
    Duan Y, Jin C, Wu Y, Chen Y, Zhang M, Qian J, Shuai T, Li J, Chen H, Li D.

    11/18/2023
    MEX3A induces the development of thyroid cancer via targeting CREB1.

    MEX3A induces the development of thyroid cancer via targeting CREB1.
    Feng G, Wang P, Zhang H, Cheng S, Xing Y, Wang Y.

    10/28/2023
    Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.

    Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.
    Liu R, Yin C, Zhao P, Guo B, Ke W, Zheng X, Xie D, Wang Y, Wang G, Jia Y, Gao Y, Hu W, Liu GL, Song Z., Free PMC Article

    10/28/2023
    Clustering of CaV 1.3 L-type calcium channels by Shank3.

    Clustering of Ca(V) 1.3 L-type calcium channels by Shank3.
    Yang Q, Perfitt TL, Quay J, Hu L, Lawson-Qureshi D, Colbran RJ., Free PMC Article

    10/11/2023
    Suppression of SLC39A6-CREB1 axis in liver cancer causes PCK1-mediated mitochondrial dysfunction.

    Suppression of SLC39A6-CREB1 axis in liver cancer causes PCK1-mediated mitochondrial dysfunction.
    Yu Z, Chen C, Gu H, Dong J, Zhang Y, Wang J, Ma H, Zhang G., Free PMC Article

    10/4/2023
    Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons.

    Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons.
    Batabyal RA, Bansal A, Cechinel LR, Authelet K, Goldberg M, Nadler E, Keene CD, Jayadev S, Domoto-Reilly K, Li G, Peskind E, Hashimoto-Torii K, Buchwald D, Freishtat RJ., Free PMC Article

    09/30/2023
    Binding of YY1/CREB to an Enhancer Region Triggers Claudin 6 Expression in H. pylori LPS-Stimulated AGS Cells.

    Binding of YY1/CREB to an Enhancer Region Triggers Claudin 6 Expression in H. pylori LPS-Stimulated AGS Cells.
    Romero-Estrada JH, Montaño LF, Rendón-Huerta EP., Free PMC Article

    09/30/2023
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