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    CRIP1 cysteine rich protein 1 [ Homo sapiens (human) ]

    Gene ID: 1396, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CRIP1 cooperates with BRCA2 to drive the nuclear enrichment of RAD51 and to facilitate homologous repair upon DNA damage induced by chemotherapy.

    CRIP1 cooperates with BRCA2 to drive the nuclear enrichment of RAD51 and to facilitate homologous repair upon DNA damage induced by chemotherapy.
    Sun H, Zhou R, Zheng Y, Wen Z, Zhang D, Zeng D, Wu J, Huang Z, Rong X, Huang N, Sun L, Bin J, Liao Y, Shi M, Liao W., Free PMC Article

    07/25/2024
    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy.

    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy.
    Tang P, Yu Z, Sun H, Liu L, Gong L, Fang T, Sun X, Xie S, An G, Xu Z, Qiu L, Hao M., Free PMC Article

    02/23/2024
    CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-kappaB/p65 nuclear translocation in pancreatic ductal adenocarcinoma.

    CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma.
    Liu X, Tang R, Xu J, Tan Z, Liang C, Meng Q, Lei Y, Hua J, Zhang Y, Liu J, Zhang B, Wang W, Yu X, Shi S., Free PMC Article

    11/30/2023
    CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/beta-catenin pathway.

    CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
    Deng X, Zeng Y, Qiu X, Zhong M, Xiong X, Luo M, Zhang J, Chen X.

    06/21/2023
    CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.

    CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
    Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L., Free PMC Article

    08/13/2022
    Comprehensive Analysis of CRIP1 in Patients with Ovarian Cancer, including ceRNA Network, Immune-Infiltration Pattern, and Clinical Benefit.

    Comprehensive Analysis of CRIP1 in Patients with Ovarian Cancer, including ceRNA Network, Immune-Infiltration Pattern, and Clinical Benefit.
    Qi B, Liu S, Liu D, Yao H, Yan R., Free PMC Article

    04/2/2022
    Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/beta-Catenin-Mediated EMT and Tumour Metastasis.

    Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
    Liu Y, Li W, Luo J, Wu Y, Xu Y, Chen T, Zhang W, Fu F., Free PMC Article

    01/8/2022
    The current research reveals a vital role of CRIP1 in colorectal cancer(CRC) progression, which provide a novel target for clinical drug resistance of colorectal cancer and undoubtedly contributing to the therapeutic strategies in CRC.

    Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation.
    Zhang L, Zhou R, Zhang W, Yao X, Li W, Xu L, Sun X, Zhao L., Free PMC Article

    06/23/2019
    CRIP1 promotes cell migration and invasion, mediates epithelial-mesenchymal transition, and activates the Wnt/betacatenin signaling pathway in cervical cancer

    CRIP1 promotes cell migration, invasion and epithelial-mesenchymal transition of cervical cancer by activating the Wnt/β‑catenin signaling pathway.
    Zhang LZ, Huang LY, Huang AL, Liu JX, Yang F.

    09/22/2018
    CRIP1 acts as an oncogene in the cell proliferation, migration, and invasion processes of thyroid carcinoma. CRIP1 may serve well as an independent prognostic marker with significant predictive power for use in thyroid carcinoma therapy.

    The Impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) on Thyroid Carcinoma.
    Li HG, Zhao LH, Zhang ZH, Liu JZ, Ren K, Li SY, Su ZJ.

    01/27/2018
    The CRIP1 expression level was highest in the highly metastatic colon cancer cell lines and CRIP1 silencing did not significantly affect the percentage of apoptotic SW620 and HT29 cells.

    Cysteine-Rich Intestinal Protein 1 Silencing Inhibits Migration and Invasion in Human Colorectal Cancer.
    He G, Zou L, Zhou L, Gao P, Qian X, Cui J.

    01/20/2018
    CRIP1 gene expression was correlated to measures of cardiac hypertrophy in Hypertension patients. Assessment of circulating CRIP1 (cystein-rich protein 1) levels as biomarkers showed a strong association with increased risk for incident stroke.

    Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.
    Zeller T, Schurmann C, Schramm K, Müller C, Kwon S, Wild PS, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann JT, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel RB, Roden M, Wahl S, Rotter JI, Ojeda F, Carstensen-Kirberg M, Tregouet DA, Dörr M, Meitinger T, Lackner KJ, Wolf P, Felix SB, Landmesser U, Costanzo S, Ziegler A, Liu Y, Völker U, Palmas W, Prokisch H, Guo X, Herder C, Blankenberg S, Homuth G., Free PMC Article

    09/30/2017
    This study provides evidence for a prognostic clinical potential of the combined study of GAL-3 and CRIP-1 in endometrial cancer

    Co-expression of galectin-3 and CRIP-1 in endometrial cancer: prognostic value and patient survival.
    Lambropoulou M, Deftereou TE, Kynigopoulos S, Patsias A, Anagnostopoulos C, Alexiadis G, Kotini A, Tsaroucha A, Nikolaidou C, Kiziridou A, Papadopoulos N, Chatzaki E.

    09/10/2016
    CRIP1 expression is associated with long-term survival and no metastases in osteosarcoma patients.

    CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients.
    Baumhoer D, Elsner M, Smida J, Zillmer S, Rauser S, Schoene C, Balluff B, Bielack S, Jundt G, Walch A, Nathrath M., Free PMC Article

    06/30/2012
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