Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function. | Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function. Carter EP, Yoneten KK, Gavara N, Tyler EJ, Gauthier V, Murray ER, Ten Dijke P, Cameron AJ, Pearce O, Grose RP., Free PMC Article | 12/16/2023 |
Association between ADAMTS14_rs4747096 gene polymorphism and bone mineral density of Chinese Han population residing in fluorine exposed areas in ShanXi Province, China. | Association between ADAMTS14_rs4747096 gene polymorphism and bone mineral density of Chinese Han population residing in fluorine exposed areas in ShanXi Province, China. Qin M, Gao Y, Zhang M, Wu J, Liu Y, Jiang Y, Zhang X, Wang X, Yang Y, Gao Y. | 11/28/2023 |
Correlation investigation between a single nucleotide polymorphism in ADAMTS14 (rs4747096) and osteoarthritis: a meta-analysis. | Correlation investigation between a single nucleotide polymorphism in ADAMTS14 (rs4747096) and osteoarthritis: a meta-analysis. Li B, Li X, Zhang L, Mou L., Free PMC Article | 08/9/2023 |
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene. | Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene. Kentistou KA, Luan J, Wittemans LBL, Hambly C, Klaric L, Kutalik Z, Speakman JR, Wareham NJ, Kendall TJ, Langenberg C, Wilson JF, Joshi PK, Morton NM., Free PMC Article | 01/28/2023 |
Survival Prognosis, Tumor Immune Landscape, and Immune Responses of ADAMTS14 in Clear Cell Renal Cell Carcinoma and Its Potential Mechanisms. | Survival Prognosis, Tumor Immune Landscape, and Immune Responses of ADAMTS14 in Clear Cell Renal Cell Carcinoma and Its Potential Mechanisms. Chen Y, Ji H, Liu S, Xing Q, Zhu B, Wang Y., Free PMC Article | 05/21/2022 |
Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing. | Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing. Li X, He Z, Zhang J, Han Y., Free PMC Article | 02/19/2022 |
The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer. | The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer. Wang Y, Zhou J, Zhang J, Cao H, Han F, Zhang H, Xu E. | 01/15/2022 |
Lack of association between MMP13 (rs3819089), ADAM12 (rs3740199-rs1871054) and ADAMTS14 (rs4747096) genotypes and advanced-stage knee osteoarthritis. | Lack of association between MMP13 (rs3819089), ADAM12 (rs3740199-rs1871054) and ADAMTS14 (rs4747096) genotypes and advanced-stage knee osteoarthritis. Haberal B, Şimşek EK, Baysan Çebi HP, Tuç Ö, Verdi H, Ataç FB., Free PMC Article | 07/24/2021 |
Inflammasome components and ADAMTS4 in premature rupture of membranes. | Inflammasome components and ADAMTS4 in premature rupture of membranes. Zhu J, Ma C, Luan X, Li J, Peng F, Huang L. | 05/8/2021 |
Our results demonstrated that circADAMTS14 might suppress hepatocellular carcinoma (HCC) progression through regulating miR-572/ RCAN1 as the competing endogenous RNA. | The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1. Song C, Li D, Liu H, Sun H, Liu Z, Zhang L, Hu Y. | 01/18/2020 |
ADAMTS14 gene polymorphism was associated with KOA, and the GG genotype increased the risk of KOA in Chinese Han population. The ADAMTS14 may be a diagnostic marker and therapeutic target for KOA treatment. | Relationship between ADAMTS14/rs4747096 gene polymorphism and knee osteoarthritis in Chinese population. Ma S, Ouyang C, Ren S., Free PMC Article | 05/18/2019 |
These results suggest an involvement of ADAMTS14 single-nucleotide polymorphisms rs12774070 and rs61573157 in the liver tumorigenesis and implicate the ADAMTS14 gene polymorphism as a predict factor during the progression of hepatocellular carcinoma. | Effects of ADAMTS14 genetic polymorphism and cigarette smoking on the clinicopathologic development of hepatocellular carcinoma. Sheu MJ, Hsieh MJ, Chou YE, Wang PH, Yeh CB, Yang SF, Lee HL, Liu YF., Free PMC Article | 08/19/2017 |
ADAMTS14 SNPs and environmental mutagens are a risk factor of oral tumorigenesis. | ADAMTS14 Gene Polymorphism and Environmental Risk in the Development of Oral Cancer. Su SC, Hsieh MJ, Liu YF, Chou YE, Lin CW, Yang SF., Free PMC Article | 07/29/2017 |
Suggest the existence of an epigenetic field defect for cancerization disrupting the methylation patterns of several loci, including MGMT or ADAMTS14, that may lead to predictive biomarkers for colorectal cancer in African Americans. | Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans. Alonso S, Dai Y, Yamashita K, Horiuchi S, Dai T, Matsunaga A, Sánchez-Muñoz R, Bilbao-Sieyro C, Díaz-Chico JC, Chernov AV, Strongin AY, Perucho M., Free PMC Article | 04/2/2016 |
Data indicate that ADAMTS2, 3 and 14 cleave the amino-propeptide of fibrillar collagens. [review] | The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology. Bekhouche M, Colige A. | 03/26/2016 |
No significant associations were observed in males. In conclusion, the nsSNP rs4747096 in ADAMTS14 was associated with knee OA in female Thai patients; therefore, the role of ADAMTS14 in OA seems to be gender-dependent. | ADAMTS14 gene polymorphism associated with knee osteoarthritis in Thai women. Poonpet T, Honsawek S, Tammachote N, Kanitnate S, Tammachote R. | 02/21/2015 |
Carriage of the ADAMTS14 rs4747096 GG variant appears to delay onset of the injury in Achilles tendon pathology. | Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study. El Khoury L, Posthumus M, Collins M, Handley CJ, Cook J, Raleigh SM. | 06/28/2014 |
ADAMTS-2, -3, and -13 expression, but not that of ADAMTS-14, are increased in plaques causing AMI compared those associated with stable angina. | Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina. Lee CW, Hwang I, Park CS, Lee H, Park DW, Kang SJ, Lee SW, Kim YH, Park SW, Park SJ. | 08/25/2012 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
findings implicate ADAMTS14 in osteoarthritis | Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes. Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco FJ, Meulenbelt I, Slagboom PE, Valdes AM, Spector TD, Gomez-Reino JJ, Gonzalez A. | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAnalysis of multiple candidate genes in association with phenotypes of multiple sclerosis. Sombekke MH, Arteta D, van de Wiel MA, Crusius JB, Tejedor D, Killestein J, Martínez A, Peña AS, Polman CH, Uitdehaag BM. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis. Goertsches R, Comabella M, Navarro A, Perkal H, Montalban X, Goertsches R, Comabella M, Navarro A, Perkal H, Montalban X. | 03/13/2008 |
This study suggest potentially important role for the ADAMTS14 gene in predisposition to MS. | Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis. Goertsches R, Comabella M, Navarro A, Perkal H, Montalban X, Goertsches R, Comabella M, Navarro A, Perkal H, Montalban X. | 01/21/2010 |