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    LINC00261 long intergenic non-protein coding RNA 261 [ Homo sapiens (human) ]

    Gene ID: 140828, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The LINC00261/MiR105-5p/SELL axis is involved in dysfunction of B cell and is associated with overall survival in hepatocellular carcinoma.

    The LINC00261/MiR105-5p/SELL axis is involved in dysfunction of B cell and is associated with overall survival in hepatocellular carcinoma.
    Song H, Huang XF, Hu SY, Lu LL, Yang XY., Free PMC Article

    01/14/2023
    The CDK1-Related lncRNA and CXCL8 Mediated Immune Resistance in Lung Adenocarcinoma.

    The CDK1-Related lncRNA and CXCL8 Mediated Immune Resistance in Lung Adenocarcinoma.
    Xue J, Song Y, Xu W, Zhu Y., Free PMC Article

    10/8/2022
    The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms.

    The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms.
    Mather RL, Parolia A, Carson SE, Venalainen E, Roig-Carles D, Jaber M, Chu SC, Alborelli I, Wu R, Lin D, Nabavi N, Jachetti E, Colombo MP, Xue H, Pucci P, Ci X, Hawkes C, Li Y, Pandha H, Ulitsky I, Marconett C, Quagliata L, Jiang W, Romero I, Wang Y, Crea F., Free PMC Article

    04/16/2022
    TGF-beta1 induced deficiency of linc00261 promotes epithelial-mesenchymal-transition and stemness of hepatocellular carcinoma via modulating SMAD3.

    TGF-β1 induced deficiency of linc00261 promotes epithelial-mesenchymal-transition and stemness of hepatocellular carcinoma via modulating SMAD3.
    Chen Z, Xiang L, Li L, Ou H, Fang Y, Xu Y, Liu Q, Hu Z, Huang Y, Li X, Yang D., Free PMC Article

    03/26/2022
    LINC00261 regulates EBF1 to suppress malignant progression of thyroid cancer.

    LINC00261 regulates EBF1 to suppress malignant progression of thyroid cancer.
    Fu XD, Liu CY, Liu YL, Su DW, Chi NN, Zhang JL, Wei WW.

    03/26/2022
    LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3.

    LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3.
    Zou J, Pei X, Xing D, Wu X, Chen S., Free PMC Article

    02/26/2022
    LINC00261 relieves the progression of sepsis-induced acute kidney injury by inhibiting NF-kappaB activation through targeting the miR-654-5p/SOCS3 axis.

    LINC00261 relieves the progression of sepsis-induced acute kidney injury by inhibiting NF-κB activation through targeting the miR-654-5p/SOCS3 axis.
    Li X, Li J, Lu P, Li M.

    02/12/2022
    LINC00261/microRNA-550a-3p/SDPR axis affects the biological characteristics of breast cancer stem cells.

    LINC00261/microRNA-550a-3p/SDPR axis affects the biological characteristics of breast cancer stem cells.
    Li Y, Wu C.

    01/29/2022
    Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription.

    Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription.
    Liu S, Zheng Y, Zhang Y, Zhang J, Xie F, Guo S, Gu J, Yang J, Zheng P, Lai J, Yin L, Wang H., Free PMC Article

    06/5/2021
    Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1.

    Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1.
    Zhai S, Xu Z, Xie J, Zhang J, Wang X, Peng C, Li H, Chen H, Shen B, Deng X., Free PMC Article

    05/1/2021
    Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in skin cutaneous melanoma.

    Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in skin cutaneous melanoma.
    Zhu J, Deng J, Zhang L, Zhao J, Zhou F, Liu N, Cai R, Wu J, Shu B, Qi S., Free PMC Article

    04/17/2021
    Identification of the 3-lncRNA Signature as a Prognostic Biomarker for Colorectal Cancer.

    Identification of the 3-lncRNA Signature as a Prognostic Biomarker for Colorectal Cancer.
    Liu S, Cao Q, An G, Yan B, Lei L., Free PMC Article

    03/6/2021
    Up-regulated LINC00261 predicts a poor prognosis and promotes a metastasis by EMT process in cholangiocarcinoma.

    Up-regulated LINC00261 predicts a poor prognosis and promotes a metastasis by EMT process in cholangiocarcinoma.
    Gao J, Qin W, Kang P, Xu Y, Leng K, Li Z, Huang L, Cui Y, Zhong X.

    11/28/2020
    LINC00261 inhibits progression of pancreatic cancer by down-regulating miR-23a-3p.

    LINC00261 inhibits progression of pancreatic cancer by down-regulating miR-23a-3p.
    Wang X, Gao X, Tian J, Zhang R, Qiao Y, Hua X, Shi G.

    10/10/2020
    Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR5525p/FOXO3 axis.

    Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
    Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B., Free PMC Article

    09/26/2020
    Upregulated long noncoding RNA Linc00261 in pre-eclampsia and its effect on trophoblast invasion and migration via regulating miR-558/TIMP4 signaling pathway.

    Upregulated long noncoding RNA Linc00261 in pre-eclampsia and its effect on trophoblast invasion and migration via regulating miR-558/TIMP4 signaling pathway.
    Cheng D, Jiang S, Chen J, Li J, Ao L, Zhang Y.

    09/5/2020
    LINC00261 represses colon cancer progression by regulating miR-324-3p expression and activity of the Wnt pathway.

    LINC00261 suppresses human colon cancer progression via sponging miR-324-3p and inactivating the Wnt/β-catenin pathway.
    Yan D, Liu W, Liu Y, Luo M.

    06/20/2020
    Data indicate that long intergenic non-protein coding RNA 261 (LINC00261) might be used as a molecular biomarker for evaluating the metastasis and recurrence-free survival of colon cancer.

    Expression and Clinical Significance of Long-chain Noncoding RNA LINC00261 in Colon Cancer.
    Zhou Z, Ma J.

    05/23/2020
    the results of the study provided evidence emphasizing the distinct antitumor ability of LINC00261 in cases of esophageal cancer, which was manifested by overexpression of LINC00261 detected to increase the sensitivity of human esophageal cancer cells to 5-FU by mediating methylation-dependent repression of DPYD.

    Long noncoding RNA LINC00261 induces chemosensitization to 5-fluorouracil by mediating methylation-dependent repression of DPYD in human esophageal cancer.
    Lin K, Jiang H, Zhuang SS, Qin YS, Qiu GD, She YQ, Zheng JT, Chen C, Fang L, Zhang SY.

    08/10/2019
    Linc00261 may serve as a new prognostic biomarker for predicting the postoperative outcomes of the patients with hepatocellular carcinoma.

    [Expression of long noncoding RNA linc00261 in hepatocellular carcinoma and its association with postoperative outcomes].
    Chen Z, Xiang L, Huang Y, Fang Y, Li X, Yang D., Free PMC Article

    02/16/2019
    LINC00261 promotes FOXO1 expression through reducing FOXO1-targeted miRNAs to suppress endometrial carcinoma cell proliferation, migration, and invasion.

    Long noncoding RNA LINC00261 regulates endometrial carcinoma progression by modulating miRNA/FOXO1 expression.
    Fang Q, Sang L, Du S.

    09/8/2018
    we also demonstrated that upregulation of LINC00261 significantly inhibited Notch signaling by downregulating Notch1 and Hes-1 expression in HCC cells.

    LINC00261 suppresses cell proliferation, invasion and Notch signaling pathway in hepatocellular carcinoma.
    Zhang HF, Li W, Han YD.

    09/1/2018
    LINC00261 inhibits cell growth and migration in endometriosis.

    Long non-coding RNA LINC00261 inhibits cell growth and migration in endometriosis.
    Sha L, Huang L, Luo X, Bao J, Gao L, Pan Q, Guo M, Zheng F, Wang H.

    06/2/2018
    our data show that the lncRNA LINC00261 was significantly downregulated in choriocarcinoma tissues and cell lines. Overexpression of LINC00261 suppresses the cell proliferation, migration, and invasion abilities in choriocarcinoma.

    Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma.
    Wang Y, Xue K, Guan Y, Jin Y, Liu S, Wang Y, Liu S, Wang L, Han L., Free PMC Article

    11/4/2017
    linc00261 acts a tumour suppressor in Gastric cancer by decreasing the stability of Slug proteins and suppressing epithelial-mesenchymal transition.

    Long non-coding RNA linc00261 suppresses gastric cancer progression via promoting Slug degradation.
    Yu Y, Li L, Zheng Z, Chen S, Chen E, Hu Y., Free PMC Article

    10/14/2017
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