Cell surface associated protein mucin 15 (MUC15) is elevated in preeclampsia. | Cell surface associated protein mucin 15 (MUC15) is elevated in preeclampsia. Nguyen A, Cannon P, Kandel M, Nguyen TV, Baird L, Wong G, Hannan NJ, Tong S, Bartho L, Kaitu'u-Lino TJ. | 09/15/2023 |
Downregulation of MUC15 by miR-183-5p.1 promotes liver tumor-initiating cells properties and tumorigenesis via regulating c-MET/PI3K/AKT/SOX2 axis. | Downregulation of MUC15 by miR-183-5p.1 promotes liver tumor-initiating cells properties and tumorigenesis via regulating c-MET/PI3K/AKT/SOX2 axis. Han T, Zheng H, Zhang J, Yang P, Li H, Cheng Z, Xiang D, Wang R., Free PMC Article | 04/23/2022 |
MUC15 loss facilitates epithelial-mesenchymal transition and cancer stemness for prostate cancer metastasis through GSK3beta/beta-catenin signaling. | MUC15 loss facilitates epithelial-mesenchymal transition and cancer stemness for prostate cancer metastasis through GSK3β/β-catenin signaling. Wu S, Yue Y, Gu Y, Wang Q, Liu T, Li L, Wang X, Chang LS, He D, Wu K. | 04/9/2022 |
Targeting MUC15 Protein in Cancer: Molecular Mechanisms and Therapeutic Perspectives. | Targeting MUC15 Protein in Cancer: Molecular Mechanisms and Therapeutic Perspectives. Zhang S, Zhang W, Xiao Y, Qin T, Yue Y, Qian W, Shen X, Ma Q, Wang Z. | 09/18/2021 |
MUC15 promotes growth and invasion of glioma cells by activating Raf/MEK/ERK pathway. | MUC15 promotes growth and invasion of glioma cells by activating Raf/MEK/ERK pathway. Cheng M, Liu L. | 07/17/2021 |
High Expression of MUC15 Is Correlated with Poor Prognosis of Pancreatic Cancer and Promotes Migration, Invasion, and Chemo-Resistance In Vitro. | High Expression of MUC15 Is Correlated with Poor Prognosis of Pancreatic Cancer and Promotes Migration, Invasion, and Chemo-Resistance In Vitro. Wang S, Li J, You L, Dai M, Zhao Y., Free PMC Article | 05/22/2021 |
MUC15 inhibits cancer metastasis via PI3K/AKT signaling in renal cell carcinoma. | MUC15 inhibits cancer metastasis via PI3K/AKT signaling in renal cell carcinoma. Yue Y, Hui K, Wu S, Zhang M, Que T, Gu Y, Wang X, Wu K, Fan J., Free PMC Article | 03/20/2021 |
Frameshift mutations of MUC15 gene is associated with gastric and colorectal cancers. | Frameshift mutations of MUC15 gene in gastric and its regional heterogeneity in gastric and colorectal cancers. Oh HR, An CH, Yoo NJ, Lee SH. | 03/12/2016 |
Multivariate analysis suggested that MUC15 overexpression was an independent factor for prognosis (hazard risk: 3.216; P=0.009). It was concluded that MUC15 is overexpressed in glioma tissues. | Correlations of MUC15 overexpression with clinicopathological features and prognosis of glioma. Yang WB, Li CY. | 09/13/2014 |
MUC15 inhibits dimerization of EGFR and PI3K-AKT signaling and is associated with aggressive hepatocellular carcinomas in patients. | MUC15 inhibits dimerization of EGFR and PI3K-AKT signaling and is associated with aggressive hepatocellular carcinomas in patients. Wang RY, Chen L, Chen HY, Hu L, Li L, Sun HY, Jiang F, Zhao J, Liu GM, Tang J, Chen CY, Yang YC, Chang YX, Liu H, Zhang J, Yang Y, Huang G, Shen F, Wu MC, Zhou WP, Wang HY. | 03/1/2014 |
MUC15 is a strong candidate for eczema. | The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma. Dizier MH, Margaritte-Jeannin P, Madore AM, Esparza-Gordillo J, Moffatt M, Corda E, Monier F, Guilloud-Bataille M, Franke A, Weidinger S, Annesi-Maesano I, Just J, Pin I, Kauffmann F, Cookson W, Lee YA, Laprise C, Lathrop M, Bouzigon E, Demenais F. | 01/26/2013 |
MUC4 and MUC15 were overexpressed in papillary thyroid carcinoma, and high MUC15 expression was associated with high malignant potential. | Expression of the membrane mucins MUC4 and MUC15, potential markers of malignancy and prognosis, in papillary thyroid carcinoma. Nam KH, Noh TW, Chung SH, Lee SH, Lee MK, Hong SW, Chung WY, Lee EJ, Park CS. | 10/29/2011 |
Overexpression of MUC15 activates extracellular signal-regulated kinase 1/2 and promotes the oncogenic potential of colon cancer cells. | Overexpression of MUC15 activates extracellular signal-regulated kinase 1/2 and promotes the oncogenic potential of human colon cancer cells. Huang J, Che MI, Huang YT, Shyu MK, Huang YM, Wu YM, Lin WC, Huang PH, Liang JT, Lee PH, Huang MC. | 01/21/2010 |
Reflux laryngitis is associated with down-regulation of mucin gene expression. | Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux. Samuels TL, Handler E, Syring ML, Pajewski NM, Blumin JH, Kerschner JE, Johnston N. | 01/21/2010 |
MUC15 was expressed most highly in human placenta. MUC15 mRNA & protein increased with gestational age (P < 0.05, 1st versus 3rd trimester). Differential expression of MUC15 in human placentas may play critical role in regulation of trophoblast invasion. | Mucin 15 is expressed in human placenta and suppresses invasion of trophoblast-like cells in vitro. Shyu MK, Lin MC, Shih JC, Lee CN, Huang J, Liao CH, Huang IF, Chen HY, Huang MC, Hsieh FJ. | 01/21/2010 |