| TFAP2C Activates CST1 Transcription to Facilitate Breast Cancer Progression and Suppress Ferroptosis. | TFAP2C Activates CST1 Transcription to Facilitate Breast Cancer Progression and Suppress Ferroptosis.
Yuan L, Zhou D, Li W, Guan J, Li J, Xu B. | 10/2/2024 |
| The functional role of CST1 and CCL26 in asthma development. | The functional role of CST1 and CCL26 in asthma development.
Hoyer A, Chakraborty S, Lilienthal I, Konradsen JR, Katayama S, Söderhäll C., Free PMC Article | 02/27/2024 |
| Combination of serum CST1 and HE4 for early diagnosis of endometrial cancer. | Combination of serum CST1 and HE4 for early diagnosis of endometrial cancer.
Zhong W, Liu Y, Zhang L, Zhuang W, Chen J, Huang Z, Zheng Y, Huang Y., Free PMC Article | 12/18/2023 |
| Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN. | Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN.
Muttuvelu DV, Cehofski LJ, Holtz J, Utheim TP, Chen X, Vorum H, Heegaard S, Rasmussen MLR, Khan AM, Abduljabar AB, Honoré B., Free PMC Article | 10/30/2023 |
| Epithelium-derived cystatin SN inhibits house dust mite protease activity in allergic asthma. | Epithelium-derived cystatin SN inhibits house dust mite protease activity in allergic asthma.
Yao L, Yuan X, Fu H, Guo Q, Wu Y, Xuan S, Kermani NZ, Adcock IM, Zeng X, Liu Y, Xie M, Yao X. | 06/7/2023 |
| Cystatin SN in type 2 inflammatory airway diseases. | Cystatin SN in type 2 inflammatory airway diseases.
Yan B, Ren Y, Liu C, Shu L, Wang C, Zhang L. | 05/13/2023 |
| MiR-942-5p inhibits tumor migration and invasion through targeting CST1 in esophageal squamous cell carcinoma. | MiR-942-5p inhibits tumor migration and invasion through targeting CST1 in esophageal squamous cell carcinoma.
Zhang L, Yu S, Yin X, Tu M, Cai L, Zhang Y, Yu L, Zhang S, Pan X, Huang Y., Free PMC Article | 03/1/2023 |
| MicroRNA-375 inhibits laryngeal squamous cell carcinoma progression via targeting CST1. | MicroRNA-375 inhibits laryngeal squamous cell carcinoma progression via targeting CST1.
Dai F, Xie Z, Yang Q, Zhong Z, Zhong C, Qiu Y., Free PMC Article | 01/11/2023 |
| Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma. | Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma.
Yang J, Luo G, Li C, Zhao Z, Ju S, Li Q, Chen Z, Ding C, Tong X, Zhao J., Free PMC Article | 06/18/2022 |
| Cystatin C and cystatin SN as possible soluble tumor markers in malignant uveal melanoma. | Cystatin C and cystatin SN as possible soluble tumor markers in malignant uveal melanoma.
Dikovskaya MA, Russkikh GS, Loktev KV, Johnston TP, Gevorgyan MM, Voronina NP, Chernykh VV, Trunov AN, Korolenko TA., Free PMC Article | 04/2/2022 |
| Prognostic and pharmacologic value of cystatin SN for chronic rhinosinusitis with nasal polyps. | Prognostic and pharmacologic value of cystatin SN for chronic rhinosinusitis with nasal polyps.
Wu D, Yan B, Wang Y, Wang C, Zhang L. | 10/23/2021 |
| The role of CST1 in hepatocellular carcinoma (HCC) progression and its potential as a latent target for HCC treatment is reported. | Upregulation of cystatin SN promotes hepatocellular carcinoma progression and predicts a poor prognosis.
Cui Y, Sun D, Song R, Zhang S, Liu X, Wang Y, Meng F, Lan Y, Han J, Pan S, Liang S, Zhang B, Guo H, Liu Y, Lu Z, Liu L., Free PMC Article | 06/27/2020 |
| CST1 enhanced eosinophil activation and recruitment through induction of IL-5. | Epithelium-derived cystatin SN enhances eosinophil activation and infiltration through IL-5 in patients with chronic rhinosinusitis with nasal polyps.
Yan B, Lou H, Wang Y, Li Y, Meng Y, Qi S, Wang M, Xiao L, Wang C, Zhang L. | 05/23/2020 |
| Human cystatin SN suppresses allergic rhinitis (AR) symptoms through inhibiting allergen protease activities and protecting the nasal TJ barrier in an allergen-specific manner. We propose that upregulation of nasal endogenous protease inhibitors, including cystatin SN, is a novel therapeutic strategy for protease allergen-induced AR. | Human cystatin SN is an endogenous protease inhibitor that prevents allergic rhinitis.
Fukuoka A, Matsushita K, Morikawa T, Adachi T, Yasuda K, Kiyonari H, Fujieda S, Yoshimoto T. | 03/21/2020 |
| CST1 was identified as one of the target genes regulated by HOXC10 in gastric cancer. CST1 knockdown represses tumorigenicity of gastric cancer cells. | HOXC10 overexpression promotes cell proliferation and migration in gastric cancer.
Kim J, Bae DH, Kim JH, Song KS, Kim YS, Kim SY., Free PMC Article | 12/28/2019 |
| The CST complex (CTC1-STN1-TEN1) maintains genome integrity through resolution of G4 structures both ahead of the replication fork and on the lagging strand template | Mammalian CST averts replication failure by preventing G-quadruplex accumulation.
Zhang M, Wang B, Li T, Liu R, Xiao Y, Geng X, Li G, Liu Q, Price CM, Liu Y, Wang F., Free PMC Article | 12/7/2019 |
| CST1 may be involved in the pathogenesis of Eosinophilic chronic rhinosinusitis (CRS), and may contribute to the severity and recurrence of CRS with nasal polyps after endoscopic sinus surgery. | Expression and Functional Analysis of CST1 in Intractable Nasal Polyps.
Kato Y, Takabayashi T, Sakashita M, Imoto Y, Tokunaga T, Ninomiya T, Morikawa T, Yoshida K, Noguchi E, Fujieda S. | 04/20/2019 |
| Results revealed that CST1 expression was upregulated in colon cancer (CC) compared with normal tissues and contributed to CC cell proliferation. | Let‑7d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway.
Jiang J, Liu HL, Tao L, Lin XY, Yang YD, Tan SW, Wu B. | 10/27/2018 |
| High CST1 expression is negatively correlated with survival of breast cancer patients. CST1 promotes cell proliferation, clone formation, and metastasis in breast cancer cells. CST1 is a novel potential prognostic biomarker and therapeutic target for breast cancer. | Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis.
Dai DN, Li Y, Chen B, Du Y, Li SB, Lu SX, Zhao ZP, Zhou AJ, Xue N, Xia TL, Zeng MS, Zhong Q, Wei WD., Free PMC Article | 04/21/2018 |
| this results identified cystatin 1 as a biomarker in patients with seasonal allergic rhinitis | Epithelial proteome profiling suggests the essential role of interferon-inducible proteins in patients with allergic rhinitis.
Ndika J, Airaksinen L, Suojalehto H, Karisola P, Fyhrquist N, Puustinen A, Alenius H. | 11/26/2017 |
| These results indicate that CST1-mediated extracellular CatB activity enhances tumor development by preventing cellular senescence. | Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation.
Oh SS, Park S, Lee KW, Madhi H, Park SG, Lee HG, Cho YY, Yoo J, Dong Kim K., Free PMC Article | 11/25/2017 |
| interactions of human family 1 & 2 cystatins with cathepsin L1 | Structural Dynamics Investigation of Human Family 1 & 2 Cystatin-Cathepsin L1 Interaction: A Comparison of Binding Modes.
Nandy SK, Seal A., Free PMC Article | 06/10/2017 |
| high expression of Cystatin SN is a significant prognostic indicator of a higher rate of recurrence, metastatic risk, and poor survival in patients with surgically resected NSCLCs. | Expression of Cystatin SN significantly correlates with recurrence, metastasis, and survival duration in surgically resected non-small cell lung cancer patients.
Cao X, Li Y, Luo RZ, Zhang L, Zhang SL, Zeng J, Han YJ, Wen ZS., Free PMC Article | 11/28/2015 |
| In conclusion, our data suggest that CST1 might contribute to the proliferation of pancreatic cancer cells and could be a potential biomarker for the early detection of pancreatic cancer. | Identification of cystatin SN as a novel biomarker for pancreatic cancer.
Jiang J, Liu HL, Liu ZH, Tan SW, Wu B. | 08/8/2015 |
| CST1 may contribute to inactivation of protease allergens and help re-establish homeostasis of the nasal membranes. | Cystatin SN upregulation in patients with seasonal allergic rhinitis.
Imoto Y, Tokunaga T, Matsumoto Y, Hamada Y, Ono M, Yamada T, Ito Y, Arinami T, Okano M, Noguchi E, Fujieda S., Free PMC Article | 03/8/2014 |