| Silencing immune-infiltrating biomarker CCDC80 inhibits malignant characterization and tumor formation in gastric cancer. | Silencing immune-infiltrating biomarker CCDC80 inhibits malignant characterization and tumor formation in gastric cancer.
Yu M, Peng J, Lu Y, Li S, Ding K., Free PMC Article | 06/26/2024 |
| Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis. | Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis.
Christian JI, Pastula A, Herbst A, Neumann J, Marschall MK, Ofner A, Zierahn H, Schneider MR, Wolf E, Quante M, Kolligs FT., Free PMC Article | 10/1/2022 |
| The expression of long non-coding RNA LINC01279 in gastric adenocarcinoma and its clinical significance. | The expression of long non-coding RNA LINC01279 in gastric adenocarcinoma and its clinical significance.
Meng S, Dolo PR, Guo P, Hong J, Li C, Zhu X, Zhou D. | 05/21/2022 |
| Plasma asprosin, CCDC80 and ANGPTL4 levels are associated with metabolic and cardiovascular risk in patients with inflammatory bowel disease. | Plasma asprosin, CCDC80 and ANGPTL4 levels are associated with metabolic and cardiovascular risk in patients with inflammatory bowel disease.
Wang HH, Luo WY, Lin M, Li XJ, Xiang GD, D Triganti S., Free PMC Article | 12/11/2021 |
| LINC01279 and MSC-AS1 were upregulated in endometriosis. LINC01279 may be associated with the pathogenesis of endometriosis. | Identification of LINC01279 as a cell cycle‑associated long non‑coding RNA in endometriosis with GBA analysis.
Liu J, Wang Q, Zhang R, Zhang C, Lin J, Huang X., Free PMC Article | 12/7/2019 |
| The authors identified that CCDC80 has genetic and functional relevance to Intracranial Aneurysm pathogenesis in the French-Canadian population. | Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population.
Zhou S, Gan-Or Z, Ambalavanan A, Lai D, Xie P, Bourassa CV, Strong S, Ross JP, Dionne-Laporte A, Spiegelman D, Dupré N, Foroud TM, Xiong L, Dion PA, Rouleau GA., Free PMC Article | 10/5/2019 |
| Our finding of upregulated CCDC80 expression in the visceral adipose tissue of obese patients indicates that it may be a component of the obesity-altered secretome in this depot. Furthermore, the presence of CCDC80 protein in human serum and its association with systemic metabolic dysfunction suggests that it may be linked to metabolic changes in other organs. | Adipose tissue and serum CCDC80 in obesity and its association with related metabolic disease.
Osorio-Conles O, Guitart M, Moreno-Navarrete JM, Escoté X, Duran X, Fernandez-Real JM, Gomez-Foix AM, Fernández-Veledo S, Vendrell J., Free PMC Article | 01/5/2019 |
| Ccdc80 is a novel betacat-regulated gene in adrenocortical cells | Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.
Walczak EM, Kuick R, Finco I, Bohin N, Hrycaj SM, Wellik DM, Hammer GD., Free PMC Article | 05/23/2015 |
| activation of PKGI with cGMP regulated SSG1 intracellular distribution. | Steroid-sensitive gene 1 is a novel cyclic GMP-dependent protein kinase I substrate in vascular smooth muscle cells.
Wang GR, Surks HK, Tang KM, Zhu Y, Mendelsohn ME, Blanton RM., Free PMC Article | 11/16/2013 |
| Data suggest that CCDC80 expression is down-regulated in many thyroid carcinomas; loss of heterozygosity partially accounts for CCDC80 down-regulation in thyroid carcinoma; CCDC80 expression positively regulates expression of E-cadherin. | Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis.
Ferraro A, Schepis F, Leone V, Federico A, Borbone E, Pallante P, Berlingieri MT, Chiappetta G, Monaco M, Palmieri D, Chiariotti L, Santoro M, Fusco A. | 10/19/2013 |
| The CCDC80 protein has three P-DUDES structural domains. These domains have significant albeit remote sequence similarity to thioredoxin-like domains and are predicted to have an oxidoreductase function. | [A case of mixed tumor of the palate].
Arlotta P, Santori L, de Vecchi A. | 05/28/2013 |
| Results reveal DRO1 as an AIB1-targeted tumor suppressor, providing a novel mechanism for AIB1-dependent inhibition of apoptosis. | Transcriptional repression of the tumor suppressor DRO1 by AIB1.
Ferragud J, Avivar-Valderas A, Pla A, De Las Rivas J, Font de Mora J. | 12/31/2011 |
| In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes. | URB is abundantly expressed in adipose tissue and dysregulated in obesity.
Okada T, Nishizawa H, Kurata A, Tamba S, Sonoda M, Yasui A, Kuroda Y, Hibuse T, Maeda N, Kihara S, Hadama T, Tobita K, Akamatsu S, Maeda K, Shimomura I, Funahashi T. | 01/21/2010 |
| Downregulated during osteoblastic differentiation of bone marrow stromal cells. Suggests role in skeletogenesis. | URB expression in human bone marrow stromal cells and during mouse development.
Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P. | 01/21/2010 |
| URB is expressed in human dermal papilla cells | URB expression in human dermal papilla cells.
Cha SY, Sung YK, Im S, Kwack MH, Kim MK, Kim JC. | 01/21/2010 |