| Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer. | Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer.
Kang N, Xie X, Zhou X, Wang Y, Chen S, Qi R, Liu T, Jiang H., Free PMC Article | 05/7/2022 |
| MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8. | MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8.
Zeng X, Ma X, Guo H, Wei L, Zhang Y, Sun C, Han N, Sun S, Zhang N., Free PMC Article | 02/19/2022 |
| Influence of CMTM8 polymorphisms on lung cancer susceptibility in the Chinese Han population. | Influence of CMTM8 polymorphisms on lung cancer susceptibility in the Chinese Han population.
Wu J, Sun Y, Xiong Z, Niu F, Liu Y, Li H, Liu J, Wu J, Liu Q, Jin T. | 10/2/2021 |
| Downregulated CMTM8 Correlates with Poor Prognosis in Gastric Cancer Patients. | Downregulated CMTM8 Correlates with Poor Prognosis in Gastric Cancer Patients.
Yan M, Zhu X, Qiao H, Zhang H, Xie W, Cai J. | 06/19/2021 |
| CMTM8 Is a Suppressor of Human Mesenchymal Stem Cell Osteogenic Differentiation and Promoter of Proliferation Via EGFR Signaling. | CMTM8 Is a Suppressor of Human Mesenchymal Stem Cell Osteogenic Differentiation and Promoter of Proliferation Via EGFR Signaling.
H'ng CH, Camp E, Anderson PJ, Zannettino ACW, Gronthos S. | 04/17/2021 |
| This is the first extensive study of CMTM8 expression in both normal and tumorous human tissues. Our findings strongly supported the potential role of CMTM8 as a novel tumor suppressor and may shape further functional studies on this gene | CMTM8 is Frequently Downregulated in Multiple Solid Tumors.
Zhang W, Qi H, Mo X, Sun Q, Li T, Song Q, Xu K, Hu H, Ma D, Wang Y. | 08/19/2017 |
| our data suggested that CMTM8 is an important tumor suppressor gene in human bladder cancer and qualified as a useful prognostic indicator for patients with bladder cancer. | Functional characterization of the tumor suppressor CMTM8 and its association with prognosis in bladder cancer.
Zhang S, Pei X, Hu H, Zhang W, Mo X, Song Q, Zhang Y, Xu K, Wang Y, Na Y. | 02/18/2017 |
| overexpression of CMTM8 in bladder cancer results in reduced malignant cell growth, migration and invasion, which could make it a potential therapeutic target in the treatment of bladder cancer. | CMTM8 inhibits the carcinogenesis and progression of bladder cancer.
Gao D, Hu H, Wang Y, Yu W, Zhou J, Wang X, Wang W, Zhou C, Xu K., Free PMC Article | 08/13/2016 |
| This study identified CMTM8 as a new candidate tumor suppressor gene and GPR177 as a new candidate oncogene in osteosarcoma. | Focal chromosomal copy number aberrations identify CMTM8 and GPR177 as new candidate driver genes in osteosarcoma.
Both J, Krijgsman O, Bras J, Schaap GR, Baas F, Ylstra B, Hulsebos TJ., Free PMC Article | 10/3/2015 |
| Down-regulation of CMTM8 also promoted an epithelial mesenchymal transition-like change in MCF-10A cells, indicating a broader role for CMTM8 in regulating cellular transformation. | Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling.
Zhang W, Mendoza MC, Pei X, Ilter D, Mahoney SJ, Zhang Y, Ma D, Blenis J, Wang Y., Free PMC Article | 06/9/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Cell proliferation and expression of EGFR of tumor cells can be inhibited by transfection of CKLFSF8. | [Effect of novel human chemokine-like factor superfamily 8 on proliferation and EGFR expression of tumor cells].
Huang YM, Du Y. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
Ollila HM, Soronen P, Silander K, Palo OM, Kieseppä T, Kaunisto MA, Lönnqvist J, Peltonen L, Partonen T, Paunio T., Free PMC Article | 04/8/2009 |
| The cloning and sequencing of an alternative splice form of CMTM8, obtained from a human blood cDNA library, that utilizes apoptotic pathways distinct from CMTM8, is reported. | An alternative splice form of CMTM8 induces apoptosis.
Li D, Jin C, Yin C, Zhang Y, Pang B, Tian L, Han W, Ma D, Wang Y. | 01/21/2010 |
| Bioinformatics based on CKLF2 cDNA and protein sequences in combination with experimental validation identified CKLFSF1-8 gene clusters, between the SCY and the TM4SF gene families. The 8 family members were cloned and characterized. | Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.
Han W, Ding P, Xu M, Wang L, Rui M, Shi S, Liu Y, Zheng Y, Chen Y, Yang T, Ma D. | 01/21/2010 |
| These data implicate CMTM8 as a negative regulator of epidermal growth factor (EGF)-induced signaling. | CMTM8 induces caspase-dependent and -independent apoptosis through a mitochondria-mediated pathway.
Jin C, Wang Y, Han W, Zhang Y, He Q, Li D, Yin C, Tian L, Liu D, Song Q, Ma D. | 01/21/2010 |
| These results identify CKLFSF8 as a novel regulator of EGF-induced signaling and indicate that the association of EGFR with four transmembrane proteins is critical for EGFR desensitization. | Regulation of EGF receptor signaling by the MARVEL domain-containing protein CKLFSF8.
Jin C, Ding P, Wang Y, Ma D. | 01/21/2010 |