| Intercellular Interactions Mediated by HGF And TGF-Beta Promote the 3D Spherical and Xenograft Growth of Liver Cancer Cells. | Intercellular Interactions Mediated by HGF And TGF-Β Promote the 3D Spherical and Xenograft Growth of Liver Cancer Cells.
Peng Z, Lv X, Zhang P, Chen Q, Zhang H, Chen J, Ma X, Ouyang B, Hao M, Tong H, Guo D, Luo Y, Huang S. | 02/1/2024 |
| Extracellular vesicles of iPS cells highly capable of producing HGF and TGF-beta1 can attenuate Sjogren's syndrome via innate immunity regulation. | Extracellular vesicles of iPS cells highly capable of producing HGF and TGF-β1 can attenuate Sjögren's syndrome via innate immunity regulation.
Ogata K, Moriyama M, Kawado T, Yoshioka H, Yano A, Matsumura-Kawashima M, Nakamura S, Kawano S. | 12/6/2023 |
| Hepatocyte growth factor attenuates high glucose-disturbed mitochondrial dynamics in podocytes by decreasing ARF6-dependent DRP1 translocation. | Hepatocyte growth factor attenuates high glucose-disturbed mitochondrial dynamics in podocytes by decreasing ARF6-dependent DRP1 translocation.
Li Y, Li X, Yang Y, Li F, Chen Q, Zhao Z, Zhang N, Li H. | 11/30/2023 |
| MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in mice. | MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in mice.
Fernandes M, Hoggard B, Jamme P, Paget S, Truong MJ, Grégoire V, Vinchent A, Descarpentries C, Morabito A, Stanislovas J, Farage E, Meneboo JP, Sebda S, Bouchekioua-Bouzaghou K, Nollet M, Humez S, Perera T, Fromme P, Grumolato L, Figeac M, Copin MC, Tulasne D, Cortot AB, Kermorgant S, Kherrouche Z., Free PMC Article | 11/7/2023 |
| Fosgonimeton, a Novel Positive Modulator of the HGF/MET System, Promotes Neurotrophic and Procognitive Effects in Models of Dementia. | Fosgonimeton, a Novel Positive Modulator of the HGF/MET System, Promotes Neurotrophic and Procognitive Effects in Models of Dementia.
Johnston JL, Reda SM, Setti SE, Taylor RW, Berthiaume AA, Walker WE, Wu W, Moebius HJ, Church KJ., Free PMC Article | 10/23/2023 |
| HGF Secreted by Menstrual Blood-Derived Endometrial Stem Cells Ameliorates Non-Alcoholic Fatty Liver Disease Through Downregulation of Hepatic Rnf186. | HGF Secreted by Menstrual Blood-Derived Endometrial Stem Cells Ameliorates Non-Alcoholic Fatty Liver Disease Through Downregulation of Hepatic Rnf186.
Du J, Jiang Y, Liu X, Ji X, Xu B, Zhang Y, Liu Y, Zhang T, Lin J. | 03/7/2023 |
| Upregulation of Reg IV and Hgf mRNAs by Intermittent Hypoxia via Downregulation of microRNA-499 in Cardiomyocytes. | Upregulation of Reg IV and Hgf mRNAs by Intermittent Hypoxia via Downregulation of microRNA-499 in Cardiomyocytes.
Takasawa S, Itaya-Hironaka A, Makino M, Yamauchi A, Sakuramoto-Tsuchida S, Uchiyama T, Shobatake R, Takeda Y, Ota H., Free PMC Article | 11/5/2022 |
| Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model. | Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model.
Wang X, Yan L, Tang Y, He X, Zhao X, Liu W, Wu Z, Luo G., Free PMC Article | 06/11/2022 |
| Resveratrol inhibited hepatocyte apoptosis and alleviated liver fibrosis through miR-190a-5p /HGF axis. | Resveratrol inhibited hepatocyte apoptosis and alleviated liver fibrosis through miR-190a-5p /HGF axis.
Liang F, Xu X, Tu Y. | 03/26/2022 |
| Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway. | Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Dong X, Luo Y, Lu S, Ma H, Zhang W, Zhu Y, Sun G, Sun X., Free PMC Article | 12/25/2021 |
| Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis. | Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis.
Dong X, Kong F, Liu C, Dai S, Zhang Y, Xiao F, Zhang H, Wu CT, Wang H., Free PMC Article | 08/7/2021 |
| HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression. | HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression.
Nishikoba N, Kumagai K, Kanmura S, Nakamura Y, Ono M, Eguchi H, Kamibayashiyama T, Oda K, Mawatari S, Tanoue S, Hashimoto S, Tsubouchi H, Ido A., Free PMC Article | 05/8/2021 |
| TLR3 promotes hepatocyte proliferation after partial hepatectomy by stimulating uPA expression and the release of tissue-bound HGF. | TLR3 promotes hepatocyte proliferation after partial hepatectomy by stimulating uPA expression and the release of tissue-bound HGF.
Stöß C, Laschinger M, Wang B, Lu M, Altmayr F, Hartmann D, Hüser N, Holzmann B. | 03/6/2021 |
| Activated Hgf-Met Signaling Cooperates with Oncogenic BRAF to Drive Primary Cutaneous Melanomas and Angiotropic Lung Metastases in Mice. | Activated Hgf-Met Signaling Cooperates with Oncogenic BRAF to Drive Primary Cutaneous Melanomas and Angiotropic Lung Metastases in Mice.
Braun AD, Mengoni M, Bonifatius S, Tüting T, Gaffal E. | 03/6/2021 |
| A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival. | A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival.
Addante A, Roncero C, Lazcanoiturburu N, Méndez R, Almalé L, García-Álvaro M, Ten Dijke P, Fabregat I, Herrera B, Sánchez A., Free PMC Article | 02/13/2021 |
| Upregulation of PDGF Mediates Robust Liver Regeneration after Nanosecond Pulsed Electric Field Ablation by Promoting the HGF/c-Met Pathway. | Upregulation of PDGF Mediates Robust Liver Regeneration after Nanosecond Pulsed Electric Field Ablation by Promoting the HGF/c-Met Pathway.
Qian J, Liu J, Hong L, Lu H, Guo D, Liu Z, Zhou L, Yin S, Zheng S., Free PMC Article | 12/19/2020 |
| Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39. | Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39.
Morell RJ, Olszewski R, Tona R, Leitess S, Wafa TT, Taukulis I, Schultz JM, Thomason EJ, Richards K, Whitley BN, Hill C, Saunders T, Starost MF, Fitzgerald T, Wilson E, Ohyama T, Friedman TB, Hoa M., Free PMC Article | 09/19/2020 |
| findings highlight that the activation of the mTOR/STAT-3 pathway provides novel mechanistic insights into MSC-secreted HGF protection against LPS-induced vascular endothelial permeability dysfunction and apoptosis, which contributes to decreasing microvascular loss and lung injury. | mTOR/STAT-3 pathway mediates mesenchymal stem cell-secreted hepatocyte growth factor protective effects against lipopolysaccharide-induced vascular endothelial barrier dysfunction and apoptosis.
Meng SS, Guo FM, Zhang XW, Chang W, Peng F, Qiu HB, Yang Y. | 06/20/2020 |
| Adipose-derived stem cell therapy ameliorates ionizing irradiation fibrosis via HGF-mediated TGFB downregulation and recruitment of bone marrow cells. | Adipose-Derived Stem Cell Therapy Ameliorates Ionizing Irradiation Fibrosis via Hepatocyte Growth Factor-Mediated Transforming Growth Factor-β Downregulation and Recruitment of Bone Marrow Cells.
Ejaz A, Epperly MW, Hou W, Greenberger JS, Rubin JP., Free PMC Article | 05/2/2020 |
| Our results suggest the importance of the microenvironmental generation of tcHGF in the regulation of development, regeneration, and stem cell behavior. | Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.
Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K., Free PMC Article | 12/7/2019 |
| these findings suggested that NMDA receptor activation may downregulate HGF by inhibiting ERK signaling in BMMSCs, thus weakening their protective effects on BLMinduced lung epithelial cell damage. | NMDA receptor activation inhibits the protective effect of BM‑MSCs on bleomycin‑induced lung epithelial cell damage by inhibiting ERK signaling and the paracrine factor HGF.
Peng X, Li X, Li C, Yue S, Huang Y, Huang P, Cheng H, Zhou Y, Tang Y, Liu W, Feng D, Luo Z., Free PMC Article | 11/30/2019 |
| Arf6 expressed in skin keratinocytes through the HGF/c-Met signaling pathway in response to skin wounding plays an important role in skin wound healing by regulating membrane dynamics-based motogenic cellular function of keratinocytes. | The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing.
Miura Y, Ngo Thai Bich V, Furuya M, Hasegawa H, Takahashi S, Katagiri N, Hongu T, Funakoshi Y, Ohbayashi N, Kanaho Y., Free PMC Article | 07/20/2019 |
| It can be assumed that Sema3a synthesized in the thymus stroma can act as a functional antagonist of HGF and KGF and have an inhibitory effect when these growth factors are administered into the body for the therapeutic purpose of restoring thymus functions. | Semaphorin 3A Negatively Affects Proliferation of Mouse Thymus Epithelial Cells In Vitro.
Rutto KV, Ovsyukov KS, Kudryavtsev IV, Kiseleva EP. | 06/1/2019 |
| Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate. | Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.
Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z., Free PMC Article | 04/13/2019 |
| c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells. | c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells.
Ko KR, Lee J, Nho B, Kim S. | 01/12/2019 |