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    ADRB1 adrenoceptor beta 1 [ Homo sapiens (human) ]

    Gene ID: 153, updated on 27-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    rs1801253 Gly/Gly carriage in the ADRB1 gene leads to unbalanced cardiac sympathetic modulation as assessed by spectral analysis of heart rate variability.

    rs1801253 Gly/Gly carriage in the ADRB1 gene leads to unbalanced cardiac sympathetic modulation as assessed by spectral analysis of heart rate variability.
    Grossini E, De Zanet D, Apostolo D, Mallela VR, La Rocca G, Greco A, Coratza G, Minisini R, Pirisi M.

    03/19/2024
    G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the beta1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells.

    G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β(1)-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells.
    Tutzauer J, Serafin DS, Schmidt T, Olde B, Caron KM, Leeb-Lundberg LMF.

    02/4/2024
    Associations between Selected ADRB1 and CYP2D6 Gene Polymorphisms in Children with Ventricular and Supraventricular Arrhythmias.

    Associations between Selected ADRB1 and CYP2D6 Gene Polymorphisms in Children with Ventricular and Supraventricular Arrhythmias.
    Moric-Janiszewska E, Smolik S, Szydłowski L, Kapral M., Free PMC Article

    01/9/2024
    An extensive beta1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies.

    An extensive β1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies.
    Tatman PD, Kao DP, Chatfield KC, Carroll IA, Wagner JA, Jonas ER, Sucharov CC, Port JD, Lowes BD, Minobe WA, Huebler SP, Karimpour-Fard A, Rodriguez EM, Liggett SB, Bristow MR., Free PMC Article

    08/25/2023
    Expression of the beta1-adrenergic receptor (ADRB1) gene in the myocardium and beta-adrenergic reactivity of the body in patients with a history of myocardium infraction.

    Expression of the β1-adrenergic receptor (ADRB1) gene in the myocardium and β-adrenergic reactivity of the body in patients with a history of myocardium infraction.
    Muslimova E, Rebrova T, Kondratieva D, Korepanov V, Sonduev E, Kozlov B, Afanasiev S.

    09/24/2022
    Genetic biomarkers of life-threatening pheochromocytoma-induced cardiomyopathy.

    Genetic biomarkers of life-threatening pheochromocytoma-induced cardiomyopathy.
    Amar J, Brunel J, Cardot Bauters C, Jacques V, Delmas C, Odou MF, Savagner F.

    05/7/2022
    Beta-adrenergic receptors gene polymorphisms are associated with cardiac contractility and blood pressure variability.

    Beta-adrenergic receptors gene polymorphisms are associated with cardiac contractility and blood pressure variability.
    Matuskova L, Czippelova B, Turianikova Z, Svec D, Kolkova Z, Lasabova Z, Javorka M., Free PMC Article

    03/26/2022
    Genetic polymorphisms in ADRB2 and ADRB1 are associated with differential survival in heart failure patients taking beta-blockers.

    Genetic polymorphisms in ADRB2 and ADRB1 are associated with differential survival in heart failure patients taking β-blockers.
    Guerra LA, Lteif C, Arwood MJ, McDonough CW, Dumeny L, Desai AA, Cavallari LH, Duarte JD., Free PMC Article

    03/12/2022
    Investigating changes in beta-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study.

    Investigating changes in β-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study.
    Tutgun Onrat S, Dural İE, Yalım Z, Onrat E., Free PMC Article

    03/5/2022
    Role of alpha- and beta-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease.

    Role of α- and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease.
    Archer M, Dogra N, Dovey Z, Ganta T, Jang HS, Khusid JA, Lantz A, Mihalopoulos M, Stockert JA, Zahalka A, Björnebo L, Gaglani S, Noh MR, Kaplan SA, Mehrazin R, Badani KK, Wiklund P, Tsao K, Lundon DJ, Mohamed N, Lucien F, Padanilam B, Gupta M, Tewari AK, Kyprianou N., Free PMC Article

    02/26/2022
    Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype.

    Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype.
    Piccini JP, Dufton C, Carroll IA, Healey JS, Abraham WT, Khaykin Y, Aleong R, Krueger SK, Sauer WH, Wilton SB, Rienstra M, van Veldhuisen DJ, Anand IS, White M, Camm AJ, Ziegler PD, Marshall D, Bristow MR, Connolly SJ, Genotype-Directed Comparative Effectiveness Trial of Bucindolol and Toprol-XL for Prevention of Atrial Fibrillation/Atrial Flutter in Patients with Heart Failure Trial Investigators*.

    01/1/2022
    Epidermal growth factor receptor association with beta1-adrenergic receptor is mediated via its juxtamembrane domain.

    Epidermal growth factor receptor association with β1-adrenergic receptor is mediated via its juxtamembrane domain.
    Patwa V, Guo S, Carter RL, Kraus L, Einspahr J, Teplitsky D, Sabri A, Tilley DG., Free PMC Article

    12/11/2021
    Visualization of beta-adrenergic receptor dynamics and differential localization in cardiomyocytes.

    Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
    Bathe-Peters M, Gmach P, Boltz HH, Einsiedel J, Gotthardt M, Hübner H, Gmeiner P, Lohse MJ, Annibale P., Free PMC Article

    12/4/2021
    The ADRB1 (Adrenoceptor Beta 1) and ADRB2 genes significantly co-express with commonly mutated genes in prostate cancer.

    The ADRB1 (Adrenoceptor Beta 1) and ADRB2 genes significantly co-express with commonly mutated genes in prostate cancer.
    Lehrer S, Rheinstein PH., Free PMC Article

    10/30/2021
    Influence of ADRB1, ADRB2, and COMT Genetic Polymorphisms on Postoperative Outcomes of Patients Undergoing Cardiac Valve Surgery.

    Influence of ADRB1, ADRB2, and COMT Genetic Polymorphisms on Postoperative Outcomes of Patients Undergoing Cardiac Valve Surgery.
    Dai S, Ma W, Qin G, Wang L, Wang E.

    07/31/2021
    Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.

    Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.
    Van Driest SL, Sleeper LA, Gelb BD, Morris SA, Dietz HC, Forbus GA, Goldmuntz E, Hoskoppal A, James J, Lee TM, Levine JC, Li JS, Loeys BL, Markham LW, Meester JAN, Mital S, Mosley JD, Olson AK, Renard M, Shaffer CM, Sharkey A, Young L, Lacro RV, Roden DM., Free PMC Article

    11/28/2020
    Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.

    Molecular basis of β-arrestin coupling to formoterol-bound β(1)-adrenoceptor.
    Lee Y, Warne T, Nehmé R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, García-Nafría J, Leslie AGW, Shukla AK, Tate CG., Free PMC Article

    11/21/2020
    Ser49Gly Beta1-Adrenergic Receptor Genetic Polymorphism as a Death Predictor in Brazilian Patients with Heart Failure.", trans "O Polimorfismo Genetico do Receptor Beta-Adrenergico Tipo 1 Ser49Gly e Preditor de Morte em Pacientes Brasileiros com Insuficiencia Cardiaca.

    Ser49Gly Beta1-Adrenergic Receptor Genetic Polymorphism as a Death Predictor in Brazilian Patients with Heart Failure.
    Albuquerque FN, Brandão AA, Silva DA, Rocha RM, Bittencourt MI, Sales ALF, Spineti PPM, Duque GS, Azevedo LRS, Pozzan R, Tura BR, Albuquerque DC., Free PMC Article

    10/31/2020
    Beta1- and Beta2-Adrenoceptors Expression Patterns in Human Non-small Cell Lung Cancer: Relationship with Cancer Histology.

    Beta1- and Beta2-Adrenoceptors Expression Patterns in Human Non-small Cell Lung Cancer: Relationship with Cancer Histology.
    Coelho M, Imperatori A, Chiaravalli AM, Franzi F, Castiglioni M, Rasini E, Luini A, Legnaro M, Marino F, Ribeiro L, Cosentino M.

    10/10/2020
    Data quantified the dynamic equilibria in the beta-1 adrenergic receptor (beta1-adrenergic receptor) in its apo form and seven ligand complexes using (1)H/(15)N NMR spectroscopy.

    A high-resolution description of β(1)-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR.
    Grahl A, Abiko LA, Isogai S, Sharpe T, Grzesiek S., Free PMC Article

    08/12/2020
    the Ser49 variant of the Ser49Gly beta1-AR gene polymorphism associates with higher renin levels. However, these common beta1-AR gene polymorphisms do not affect blood pressure in the same cohort

    β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients.
    Sandilands AJ, O'Shaughnessy KM., Free PMC Article

    07/11/2020
    High ADRB1 expression is associated with male infertility.

    β-adrenergic receptors in the up-regulation of COX2 expression and prostaglandin production in testicular macrophages: Possible relevance to male idiopathic infertility.
    Matzkin ME, Riviere E, Rossi SP, Ponzio R, Puigdomenech E, Levalle O, Terradas C, Calandra RS, Mayerhofer A, Frungieri MB.

    06/27/2020
    Patients with heart failure and reduced ejection fraction that are homozygous for ADRB1 Ser49 genetic polymorphisms were significantly more likely to experience left ventricular ejection fraction recovery than Gly49 carriers.

    Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.
    Luzum JA, English JD, Ahmad US, Sun JW, Canan BD, Sadee W, Kitzmiller JP, Binkley PF., Free PMC Article

    06/13/2020
    beta1AR A187V mutation is associated with familial natural short sleep.

    A Rare Mutation of β(1)-Adrenergic Receptor Affects Sleep/Wake Behaviors.
    Shi G, Xing L, Wu D, Bhattacharyya BJ, Jones CR, McMahon T, Chong SYC, Chen JA, Coppola G, Geschwind D, Krystal A, Ptáček LJ, Fu YH., Free PMC Article

    03/28/2020
    Beta1-adrenergic receptor autoantibody induces cardiac remodeling by activating t-lymphocytes.

    Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling.
    Du Y, Li X, Yu H, Yan L, Lau WB, Zhang S, Qin Y, Wang W, Ma X, Liu H, Fu M.

    02/22/2020
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