| Physical contact between cytochrome c1 and cytochrome c increases the driving force for electron transfer. | Physical contact between cytochrome c(1) and cytochrome c increases the driving force for electron transfer.
Pérez-Mejías G, Olloqui-Sariego JL, Guerra-Castellano A, Díaz-Quintana A, Calvente JJ, Andreu R, De la Rosa MA, Díaz-Moreno I. | 12/5/2020 |
| CYC1 inhibits cell proliferation, glycolytic activity and increases chemosensitivity to paclitaxel in ER-positive breast carcinoma cells | Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma.
Sato A, Takagi K, Miki Y, Yoshimura A, Hara M, Ishida T, Sasano H, Suzuki T. | 05/23/2020 |
| these results indicate that CYC1 plays important roles in cell proliferation and comedo necrosis through the elevated oxidative phosphorylation activity in human ductal carcinoma in situ | Cytochrome c1 in ductal carcinoma in situ of breast associated with proliferation and comedo necrosis.
Chishiki M, Takagi K, Sato A, Miki Y, Yamamoto Y, Ebata A, Shibahara Y, Watanabe M, Ishida T, Sasano H, Suzuki T., Free PMC Article | 09/16/2017 |
| results indicate that miR-661 plays a tumor suppressor role in OS mediated by the downregulation of CYC1, suggesting a potential mechanism underlying cell death resistance in Osteosarcoma. | MicroRNA-661 Enhances TRAIL or STS Induced Osteosarcoma Cell Apoptosis by Modulating the Expression of Cytochrome c1.
Fan L, Zhu C, Qiu R, Zan P, Zheng Z, Xu T, Li G. | 06/24/2017 |
| CYC1 promoted tumor metastasis via suppressing activation of AMPK and contributed to tumor growth via facilitating production of ATP. | CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Han Y, Sun S, Zhao M, Zhang Z, Gong S, Gao P, Liu J, Zhou J, Ma D, Gao Q, Wu P., Free PMC Article | 02/25/2017 |
| FASL, granzyme B, and cytochrome c blood expression reflects breast cancer progression and response to therapy. (Review) | Apoptosis Markers in Breast Cancer Therapy.
Kadam CY, Abhang SA. | 08/20/2016 |
| our results provide evidence that CYC1 plays an important role in OS tumorigenesis, and modulation of CYC1 may be an effective strategy to potentiate OS to apoptotic induction by TRAIL. | CYC1 silencing sensitizes osteosarcoma cells to TRAIL-induced apoptosis.
Li G, Fu D, Liang W, Fan L, Chen K, Shan L, Hu S, Ma X, Zhou K, Cheng B. | 10/3/2015 |
| Mutations in CYC1 cause insulin-responsive hyperglycemia. | Mutations in CYC1, encoding cytochrome c1 subunit of respiratory chain complex III, cause insulin-responsive hyperglycemia.
Gaignard P, Menezes M, Schiff M, Bayot A, Rak M, Ogier de Baulny H, Su CH, Gilleron M, Lombes A, Abida H, Tzagoloff A, Riley L, Cooper ST, Mina K, Sivadorai P, Davis MR, Allcock RJ, Kresoje N, Laing NG, Thorburn DR, Slama A, Christodoulou J, Rustin P., Free PMC Article | 12/21/2013 |
| HeLa cells expressing non-cleavable cytochrome c1 maintain mitochondrial morphology and functions. | Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release.
Zhu Y, Li M, Wang X, Jin H, Liu S, Xu J, Chen Q., Free PMC Article | 05/5/2012 |
| Decreased electron Transport Complex IV activity is associated with ulcerative colitis. | Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis.
Sifroni KG, Damiani CR, Stoffel C, Cardoso MR, Ferreira GK, Jeremias IC, Rezin GT, Scaini G, Schuck PF, Dal-Pizzol F, Streck EL. | 01/8/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article | 12/5/2010 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)., Free PMC Article | 09/15/2010 |
| Sensitivity of Cyt c detection in -linked immunosorbent assay is reduced in the presence of serum leucine-rich alpha-2-glycoprotein-1. | Serum leucine-rich alpha-2-glycoprotein-1 binds cytochrome c and inhibits antibody detection of this apoptotic marker in enzyme-linked immunosorbent assay.
Cummings C, Walder J, Treeful A, Jemmerson R. | 01/21/2010 |
| the Ca(2+) spike, mitochondrial Bcl-2 presensitization, and subsequent Delta psi(m) transition, Bax translocation, and ROS generation are important upstream signals for cytochrome c release upon stimulation by a Bcl-2 inhibitor. | Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor.
An J, Chen Y, Huang Z. | 01/21/2010 |
| Addition of H202 to tendon fibroblasts in vitro resulted in oxidative stress-induced apoptosis and the release of CYC1. | Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts.
Yuan J, Murrell GA, Trickett A, Wang MX. | 01/21/2010 |