| Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12. | Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12.
Li M, Li L, Cheng X, Li L, Tu K. | 01/10/2024 |
| Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12. | Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12.
Cao B, Zhao R, Li H, Xu X, Gao J, Chen L, Wei B., Free PMC Article | 01/14/2023 |
| Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro. | Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro.
Pehlivanoglu S, Sahan OB, Pehlivanoglu S, Aktas Kont K. | 03/26/2022 |
| Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect. | Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect.
Shi Y, Zhang Y, Ran F, Liu J, Lin J, Hao X, Ding L, Ye Q. | 03/28/2021 |
| Alternative Splicing and Cleavage of GLUT8. | Alternative Splicing and Cleavage of GLUT8.
Alexander CM, Martin JA, Oxman E, Kasza I, Senn KA, Dvinge H., Free PMC Article | 02/13/2021 |
| We hypothesize that GLUT12 would contribute to modulate sugar absorption in physiological and pathophysiological situations such as obesity. | GLUT12 and adipose tissue: Expression, regulation and its relation with obesity in mice.
Gil-Iturbe E, Arbones-Mainar JM, Moreno-Aliaga MJ, Lostao MP. | 08/12/2020 |
| GLUT12 rapid translocation to the enterocytes apical membrane in response to glucose and insulin could be related to GLUT12 participation in sugar absorption during postprandial periods. In the pathological condition of obesity, in which insulin sensitivity is reduced, the contribution of GLUT12 to sugar absorption would be affected. | GLUT12 expression and regulation in murine small intestine and human Caco-2 cells.
Gil-Iturbe E, Castilla-Madrigal R, Barrenetxe J, Villaro AC, Lostao MP. | 03/21/2020 |
| GLUT12-knockdown completely abrogated high glucose-induced migration, indicating that GLUT12 functionally participates in sensing high glucose concentrations. | Potential Roles of GLUT12 for Glucose Sensing and Cellular Migration in MCF-7 Human Breast Cancer Cells Under High Glucose Conditions.
Matsui C, Takatani-Nakase T, Maeda S, Nakase I, Takahashi K. | 12/23/2017 |
| GLUT12 is a versatile transporter: it transports a wide diversity of hexoses, it can work as a Na+ or H+/glucose symporter, and it shows electrogenic properties. | Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods.
Pujol-Giménez J, Pérez A, Reyes AM, Loo DD, Lostao MP. | 08/30/2015 |
| findings show the level of expression of GLUT12 was significantly higher in Alzheimer's disease compare to aged controls | Expression of the glucose transporter GLUT12 in Alzheimer's disease patients.
Pujol-Gimenez J, Martisova E, Perez-Mediavilla A, Lostao MP, Ramirez MJ. | 05/16/2015 |
| Intestinal dehydroascorbic acid (DHA) transport is mediated by the facilitative sugar transporters, GLUT2 and GLUT8 | Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.
Corpe CP, Eck P, Wang J, Al-Hasani H, Levine M., Free PMC Article | 06/1/2013 |
| study provides the first direct evidence for GLUT9 and GLUT12 expression in vascular smooth muscle cells in conjunction with the previously identified GLUT1 and GLUT10 | Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells.
Pyla R, Poulose N, Jun JY, Segar L., Free PMC Article | 05/11/2013 |
| Translocation of GLUT12 in cultured myoblasts was dependent on activation of PI3-K. | Insulin-stimulated translocation of glucose transporter (GLUT) 12 parallels that of GLUT4 in normal muscle.
Stuart CA, Howell ME, Zhang Y, Yin D., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesGenetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. A large-scale candidate gene association study of age at menarche and age at natural menopause.
He C, Kraft P, Chasman DI, Buring JE, Chen C, Hankinson SE, Paré G, Chanock S, Ridker PM, Hunter DJ. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML. | 11/16/2008 |
| GLUT4 and GLUT12 were predominantly expressed in type I oxidative fibers; however, GLUT5 was expressed predominantly in type II (white) fibers | Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle.
Stuart CA, Yin D, Howell ME, Dykes RJ, Laffan JJ, Ferrando AA. | 01/21/2010 |
| Glucose transport properties and hexose affinities of GLUT12. | Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes.
Rogers S, Chandler JD, Clarke AL, Petrou S, Best JD. | 01/21/2010 |
| expression in adipose tissue | Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.
Wood IS, Hunter L, Trayhurn P. | 01/21/2010 |
| GLUT12 protein was localized to the apical membrane of human and rat distal tubules and collecting ducts. Levels of both GLUT1 and GLUT12 are elevated in animal models of hypertension and diabetic nephropathy. | Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy.
Linden KC, DeHaan CL, Zhang Y, Glowacka S, Cox AJ, Kelly DJ, Rogers S. | 01/21/2010 |
| Embedded in microvillous (maternal-facing) and basal (fetal-facing) membranes of syncytiotrophoblast, main placental barrier layer. (review) | Placental glucose transfer and fetal growth.
Baumann MU, Deborde S, Illsley NP. | 01/21/2010 |