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    CYP11B2 cytochrome P450 family 11 subfamily B member 2 [ Homo sapiens (human) ]

    Gene ID: 1585, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of combined -344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population.

    Association of combined -344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population.
    Nouhi Y, Aboubakr FZ, Brini OE, Benazzouz B, Akhouayri O.

    08/28/2024
    Identification of a Novel CYP11B2 Variant in a Family with Varying Degrees of Aldosterone Synthase Deficiency.

    Identification of a Novel CYP11B2 Variant in a Family with Varying Degrees of Aldosterone Synthase Deficiency.
    Garrelfs MR, Rinne T, Hillebrand JJ, Lauffer P, Bijlsma MW, Claahsen-van der Grinten HL, de Leeuw N, Finken MJJ, Rotteveel J, Zwaveling-Soonawala N, Nieuwdorp M, van Trotsenburg ASP, Mooij CF., Free PMC Article

    03/12/2024
    Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan.

    Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan.
    Shah WA, Jan A, Khan MA, Saeed M, Rahman N, Zakiullah, Afridi MS, Khuda F, Akbar R., Free PMC Article

    06/30/2023
    Functional nodules in primary aldosteronism: identification of CXCR4 expression with [68]Ga-pentixafor PET/CT.

    Functional nodules in primary aldosteronism: identification of CXCR4 expression with (68)Ga-pentixafor PET/CT.
    Gao Y, Ding J, Cui Y, Li T, Sun H, Zhao D, Zhang Y, Huo L, Tong A.

    02/11/2023
    Changes of the CYP11B2 Expressing Zona Glomerulosa in Human Adrenals From Birth to 40 Years of Age.

    Changes of the CYP11B2 Expressing Zona Glomerulosa in Human Adrenals From Birth to 40 Years of Age.
    van de Wiel E, Chaman Baz AH, Küsters B, Mukai K, van Bonzel L, van Erp M, Deinum J, Langenhuijsen J.

    11/26/2022
    Contribution of the ACE (rs1799752) and CYP11B2 (rs1799998) Gene Polymorphisms to Atrial Fibrillation in the Tunisian Population.

    Contribution of the ACE (rs1799752) and CYP11B2 (rs1799998) Gene Polymorphisms to Atrial Fibrillation in the Tunisian Population.
    Gouissem I, Midani F, Soualmia H, Bouchemi M, Ouali S, Kallele A, Romdhane NB, Mourali MS, Feki M.

    05/7/2022
    Effect of ACE, ACE2 and CYP11B2 gene polymorphisms and noise on essential hypertension among steelworkers in China: a case-control study.

    Effect of ACE, ACE2 and CYP11B2 gene polymorphisms and noise on essential hypertension among steelworkers in China: a case-control study.
    Zhang X, Wang Y, Zheng Y, Yuan J, Tong J, Xu J, Li Q, Li P, Jiang S, Wang Z, Chai F, Li X., Free PMC Article

    04/16/2022
    Clinical and Genetic Characteristics of Patients with Corticosterone Methyloxidase Deficiency Type 2: Novel Mutations in CYP11B2

    Clinical and Genetic Characteristics of Patients with Corticosterone Methyloxidase Deficiency Type 2: Novel Mutations in CYP11B2.
    Turan H, Dağdeviren Çakır A, Özer Y, Tarçın G, Özcabi B, Ceylaner S, Ercan O, Evliyaoğlu SO., Free PMC Article

    03/19/2022
    Catch-up Growth and Discontinuation of Fludrocortisone Treatment in Aldosterone Synthase Deficiency.

    Catch-up Growth and Discontinuation of Fludrocortisone Treatment in Aldosterone Synthase Deficiency.
    Gurpinar Tosun B, Kendir Demirkol Y, Seven Menevse T, Kaygusuz SB, Ozbek MN, Altincik SA, Mammadova J, Cayir A, Doger E, Bayramoglu E, Nalbantoglu O, Yesiltepe Mutlu G, Aghayev A, Turan S, Bereket A, Guran T.

    02/19/2022
    Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.

    Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.
    Ahn CH, Na HY, Park SY, Yu HW, Kim SJ, Choi JY, Lee KE, Kim SW, Jung KC, Kim JH.

    01/29/2022
    GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.

    GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.
    Wu YC, Chen CI, Chen PY, Kuo CH, Hung YH, Peng KY, Wu VC, Tsai-Wu JJ, Hsu CL, TAIPAI group., Free PMC Article

    01/15/2022
    ALDOSTERONE SYNTHASE GENE capital ES, Cyrillic-344capital TE, Cyrillic POLYMORPHISM AS A RISK FACTOR OF EARLY LEFT VENTRICULAR REMODELING IN YOUNG HYPERTENSIVE PATIENTS WITH OBESITY.

    ALDOSTERONE SYNTHASE GENE С-344Т POLYMORPHISM AS A RISK FACTOR OF EARLY LEFT VENTRICULAR REMODELING IN YOUNG HYPERTENSIVE PATIENTS WITH OBESITY.
    Yakimenko O, Chernyshova K, Bondar V, Klochko V, Kolomiets S, Tbilieli V.

    12/18/2021
    Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin.

    Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin.
    Brixius-Anderko S, Scott EE., Free PMC Article

    09/4/2021
    Molecular Analysis of the CYP11B2 Gene in 62 Patients with Hypoaldosteronism Due to Aldosterone Synthase Deficiency.

    Molecular Analysis of the CYP11B2 Gene in 62 Patients with Hypoaldosteronism Due to Aldosterone Synthase Deficiency.
    Merakou C, Fylaktou I, Sertedaki A, Dracopoulou M, Voutetakis A, Efthymiadou A, Christoforidis A, Dacou-Voutetakis C, Chrysis D, Kanaka-Gantenbein C.

    09/4/2021
    Aldosterone synthase (CYP11B2) deficiency among Palestinian infants: Three novel variants and genetic heterogeneity.

    Aldosterone synthase (CYP11B2) deficiency among Palestinian infants: Three novel variants and genetic heterogeneity.
    Faingelernt Y, Hershkovitz E, Abu-Libdeh B, Abedrabbo A, Abu-Rmaileh Amro S, Zarivach R, Zangen D, Lavi E, Haim A, Parvari R, Abu-Libdeh A.

    08/7/2021
    Lack of association between CYP11B2 -344T/C polymorphism and transient ischemic attack in a Chinese population.

    Lack of association between CYP11B2 -344T/C polymorphism and transient ischemic attack in a Chinese population.
    Fan J, Shen Y, Chen B, Xu C, Ye H, Wang J, Zhou W, Sheng Y, Xu F, Yang P., Free PMC Article

    07/10/2021
    DNA Methylation of the Angiotensinogen Gene, AGT, and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases.

    DNA Methylation of the Angiotensinogen Gene, AGT, and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases.
    Takeda Y, Demura M, Yoneda T, Takeda Y., Free PMC Article

    06/12/2021
    The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.

    The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.
    Sydorchuk L, Dzhuryak V, Sydorchuk A, Levytska S, Petrynych V, Knut R, Kshanovska A, Iftoda O, Tkachuk O, Kyfiak P, Popovich A, Khomko O, Sydorchuk R.

    06/5/2021
    Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system.

    Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system.
    Yablokov EO, Sushko TA, Kaluzhskiy LA, Kavaleuski AA, Mezentsev YV, Ershov PV, Gilep AA, Ivanov АS, Strushkevich NV.

    05/8/2021
    Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione oxidation.

    Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione oxidation.
    Glass SM, Reddish MJ, Child SA, Wilkey CJ, Stec DF, Guengerich FP., Free PMC Article

    05/8/2021
    Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.

    Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.
    Wang L, Zhang Z, Liu D, Yuan K, Zhu G, Qi X., Free PMC Article

    05/8/2021
    Immunohistochemistry of the Human Adrenal CYP11B2 in Normal Individuals and in Patients with Primary Aldosteronism.

    Immunohistochemistry of the Human Adrenal CYP11B2 in Normal Individuals and in Patients with Primary Aldosteronism.
    Gomez-Sanchez CE, Gomez-Sanchez EP, Nishimoto K., Free PMC Article

    04/3/2021
    Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.

    Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.
    Mopidevi B, Sivankutty I, Hao S, Ferreri NR, Kumar A., Free PMC Article

    02/20/2021
    Correlation between CYP11B2 polymorphism and the risk of preeclampsia.

    Correlation between CYP11B2 polymorphism and the risk of preeclampsia.
    Wang Y, Zhou M, Deng X, Ma Y, Jiang D., Free PMC Article

    12/12/2020
    CYP11B2 -344C/T polymorphism and -344T allele are associated with left ventricular hypertrophy which may predispose to cardiovascular complications of hypertension

    Association of aldosterone synthase CYP11B2 (-344C/T) gene polymorphism with essential hypertension and left ventricular hypertrophy in the Egyptian population.
    Abdel Ghafar MT.

    08/13/2020
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