| Global spread characteristics of CTX-M-type extended-spectrum beta-lactamases: A genomic epidemiology analysis. | Global spread characteristics of CTX-M-type extended-spectrum β-lactamases: A genomic epidemiology analysis.
Yu K, Huang Z, Xiao Y, Gao H, Bai X, Wang D. | 03/11/2024 |
| Cerebrotendinous Xanthomatosis patients with late diagnosed in single orthopedic clinic: two novel variants in the CYP27A1 gene. | Cerebrotendinous Xanthomatosis patients with late diagnosed in single orthopedic clinic: two novel variants in the CYP27A1 gene.
Köroğlu M, Karakaplan M, Gündüz E, Kesriklioğlu B, Ergen E, Aslantürk O, Özdemir ZM., Free PMC Article | 02/15/2024 |
| 27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor. | 27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor.
Ayadi S, Friedrichs S, Soulès R, Pucheu L, Lütjohann D, Silvente-Poirot S, Poirot M, de Medina P., Free PMC Article | 01/3/2024 |
| The Interaction Effect of 27-Hydroxycholesterol Metabolism Disorder and CYP27A1 Single Nucleotide Polymorphisms in Mild Cognitive Impairment: Evidence from a Case-Control Study. | The Interaction Effect of 27-Hydroxycholesterol Metabolism Disorder and CYP27A1 Single Nucleotide Polymorphisms in Mild Cognitive Impairment: Evidence from a Case-Control Study.
Wang L, Yu H, Hao L, Ju M, Feng W, Xiao R. | 08/25/2023 |
| TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1. | TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1.
Wang X, Shi J, Huang M, Chen J, Dan J, Tang Y, Guo Z, He X, Zhao Q., Free PMC Article | 08/9/2023 |
| Analysis of CYP27A1 mutations in Han Chinese women with intrahepatic cholestasis of pregnancy. | Analysis of CYP27A1 mutations in Han Chinese women with intrahepatic cholestasis of pregnancy.
Xin S, Liu X, Liu H, Zeng X, Xiong Y, Zhou M, Zou Y, Zeng Y, Zheng J, Lai H. | 11/26/2022 |
| CYP27A1 inhibits proliferation and migration of clear cell renal cell carcinoma via activation of LXRs/ABCA1. | CYP27A1 inhibits proliferation and migration of clear cell renal cell carcinoma via activation of LXRs/ABCA1.
Liang Z, Jiao W, Wang L, Chen Y, Li D, Zhang Z, Zhang Z, Liang Y, Niu H. | 09/10/2022 |
| The tumor-repressing effect of CYP27A1 on renal cell carcinoma by 27-HC arising from cholesterol metabolism. | The tumor-repressing effect of CYP27A1 on renal cell carcinoma by 27-HC arising from cholesterol metabolism.
Zhang X, Yin X, Dai J, Sun G, Zhang H, Liang J, Zhao J, Zhu S, Chen J, Zhu X, Ni Y, Wang Z, Liu Z, Chen N, Shen P, Zeng H. | 08/20/2022 |
| CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. | CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism.
Cho H, Shen Q, Zhang LH, Okumura M, Kawakami A, Ambrose J, Sigoillot F, Miller HR, Gleim S, Cobos-Correa A, Wang Y, Piechon P, Roma G, Eggimann F, Moore C, Aspesi P Jr, Mapa FA, Burks H, Ross NT, Krastel P, Hild M, Maimone TJ, Fisher DE, Nomura DK, Tallarico JA, Canham SM, Jenkins JL, Forrester WC., Free PMC Article | 01/8/2022 |
| A case of Cerebrotendinous Xanthomatosis with spinal cord involvement and without tendon xanthomas: identification of a new mutation of the CYP27A1 gene. | A case of Cerebrotendinous Xanthomatosis with spinal cord involvement and without tendon xanthomas: identification of a new mutation of the CYP27A1 gene.
Gelzo M, Di Taranto MD, Bisecco A, D'Amico A, Capuano R, Giacobbe C, Caputo M, Cirillo M, Tedeschi G, Fortunato G, Corso G. | 11/6/2021 |
| Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study. | Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study.
Sadeghi H, Kamaliyan Z, Mohseni R, Sahebi U, Nazemalhosseini-Mojarad E, Aghaei N, Zali MR, Asadzadeh Aghdaei H, Mirfakhraie R, Moshiri A., Free PMC Article | 10/30/2021 |
| Clinical and Genetic Characteristics of Splicing Variant in CYP27A1 in an Iranian Family with Cerebrotendinous Xanthomatosis. | Clinical and Genetic Characteristics of Splicing Variant in CYP27A1 in an Iranian Family with Cerebrotendinous Xanthomatosis.
Rashvand Z, Kahrizi K, Najmabadi H, Najafipour R, Omrani MD., Free PMC Article | 10/9/2021 |
| CYP2R1 and CYP27A1 genes: An in silico approach to identify the deleterious mutations, impact on structure and their differential expression in disease conditions. | CYP2R1 and CYP27A1 genes: An in silico approach to identify the deleterious mutations, impact on structure and their differential expression in disease conditions.
Sunkar S, Neeharika D. | 10/9/2021 |
| Extending the vitamin D pathway to vitamin D3 and CYP27A1 in periodontal ligament cells. | Extending the vitamin D pathway to vitamin D(3) and CYP27A1 in periodontal ligament cells.
Zhang C, Liu K, Hou J. | 09/18/2021 |
| CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients. | CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients.
Kimbung S, Inasu M, Stålhammar T, Nodin B, Elebro K, Tryggvadottir H, Ygland Rödström M, Jirström K, Isaksson K, Jernström H, Borgquist S., Free PMC Article | 06/26/2021 |
| Relationship between rs4674344 CYP27A1 gene polymorphism and coronary artery disease in a Polish population. | Relationship between rs4674344 CYP27A1 gene polymorphism and coronary artery disease in a Polish population.
Iwanicka J, Iwanicki T, Balcerzyk A, Niemiec P, Nowak T, Krauze J, Trautsolt W, Ochalska-Tyka A, Grzeszczak W, Żak I. | 05/8/2021 |
| Low CYP27A1 expression is associated with higher cholesterol synthesis and a higher risk of Lethal Prostate Cancer. | Intratumoral Sterol-27-Hydroxylase (CYP27A1) Expression in Relation to Cholesterol Synthesis and Vitamin D Signaling and Its Association with Lethal Prostate Cancer.
Khan NA, Stopsack KH, Allott EH, Gerke T, Giovannucci EL, Mucci LA, Kantoff PW., Free PMC Article | 08/12/2020 |
| These findings all suggest that CYP27A1 is a critical cholesterol sensor in bladder cancer cells that may contribute significantly to bladder cancer proliferation. | CYP27A1 inhibits bladder cancer cells proliferation by regulating cholesterol homeostasis.
Liang Z, Chen Y, Wang L, Li D, Yang X, Ma G, Wang Y, Li Y, Zhao H, Liang Y, Niu H., Free PMC Article | 02/22/2020 |
| Study found no statistically significant associations of HCV infection outcomes with CYP27A1 gene. | Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.
Yang JJ, Fan HZ, Tian T, Wu MP, Xie CN, Huang P, Yu RB, Yi HG, Zhang Y, Wang J. | 11/9/2019 |
| analysis of the role of CYP27A1, CYP27B1, and CYP24A1 in non-melanoma skin cancer reveals that the expression of CYP27A1 and CYP24A1, but not CYP27B1 is changed in malignant cells | Vitamin D enzymes (CYP27A1, CYP27B1, and CYP24A1) and receptor expression in non-melanoma skin cancer.
Nemazannikova N, Blatch GL, Dass CR, Sinclair R, Apostolopoulos V. | 10/26/2019 |
| Donor/recipient CYP27A1 rs4674344 and graft VDR rs2228570 may be related to low serum 25(OH)D and may play a major role in the development of fatty liver disease in recipients after living donor liver transplantation. | Genetic polymorphisms of the hepatic pathways of fatty liver disease after living donor liver transplantation.
Chiu KW, Goto S, Nakano T, Hu TH, Chen DW, Huang KT, Hsu LW, Chen CL. | 08/10/2019 |
| CYP27A1 SNPs are not associated with vitamin D status and multiple sclerosis. | CYP27A1, CYP24A1, and RXR-α Polymorphisms, Vitamin D, and Multiple Sclerosis: a Pilot Study.
Agnello L, Scazzone C, Lo Sasso B, Ragonese P, Milano S, Salemi G, Ciaccio M. | 11/10/2018 |
| Vitamin D supplementation can decrease circulating 27HC of breast cancer patients, likely by CYP27A1 inhibition. This suggests a new and additional modality by which vitamin D can inhibit ER+ breast cancer growth, though a larger study is needed for verification. | Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial.
Going CC, Alexandrova L, Lau K, Yeh CY, Feldman D, Pitteri SJ., Free PMC Article | 10/27/2018 |
| Whole-exome sequencing assuming recessive inheritance determined his genetic diagnosis to be cerebrotendinous xanthomatosis caused by homozygous mutations (c.410G>A or p.Arg137Gln) in the cytochrome P450 subfamily 27 A1 (CYP27A1) gene | Prominent Tendon Xanthomas and Abdominal Aortic Aneurysm Associated with Cerebrotendinous Xanthomatosis Identified Using Whole Exome Sequencing.
Tada H, Inaba S, Pozharitckaia D, Kawashiri MA., Free PMC Article | 09/1/2018 |
| Three novel mutations in CYP27A1 were found in cerebrotendinous xanthomatosis patients in Chinese families | Clinical and molecular genetic features of cerebrotendinous xanthomatosis patients in Chinese families.
Chen C, Zhang Y, Wu H, Sun YM, Cai YH, Wu JJ, Wang J, Gong LY, Ding ZT. | 07/28/2018 |