U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    DDX5 DEAD-box helicase 5 [ Homo sapiens (human) ]

    Gene ID: 1655, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.

    AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
    Tian W, Tang Y, Luo Y, Xie J, Zheng S, Zou Y, Huang X, Wu L, Zhang J, Sun Y, Tang H, Du W, Li X, Xie X., Free PMC Article

    12/6/2023
    DDX5 (p68) orchestrates beta-catenin, RelA and SP1 mediated MGMT gene expression in human colon cancer cells: Implication in TMZ chemoresistance.

    DDX5 (p68) orchestrates β-catenin, RelA and SP1 mediated MGMT gene expression in human colon cancer cells: Implication in TMZ chemoresistance.
    Shaw R, Karmakar S, Basu M, Ghosh MK.

    11/20/2023
    Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence.

    Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence.
    Li F, Ling X, Chakraborty S, Fountzilas C, Wang J, Jamroze A, Liu X, Kalinski P, Tang DG., Free PMC Article

    08/28/2023
    Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation.

    Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation.
    Leszczynska KB, Dzwigonska M, Estephan H, Moehlenbrink J, Bowler E, Giaccia AJ, Mieczkowski J, Kaminska B, Hammond EM., Free PMC Article

    07/17/2023
    The DEAD-box RNA helicase DDX5 (p68) and beta-catenin: The crucial regulators of FOXM1 gene expression in arbitrating colorectal cancer.

    The DEAD-box RNA helicase DDX5 (p68) and β-catenin: The crucial regulators of FOXM1 gene expression in arbitrating colorectal cancer.
    Tabassum S, Basu M, Ghosh MK.

    06/2/2023
    Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5.

    Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5.
    Che Y, Bai M, Lu K, Fu L.

    01/28/2023
    Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis.

    Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis.
    Wang T, Qin Y, Chen J, Chen S, Wu J, Chen X, Chen X, Zhou S, Zou J, Guan J., Free PMC Article

    10/22/2022
    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth.

    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth.
    Gualtieri A, Bianconi V, Renzini A, Pieroni L, Licursi V, Mozzetta C.

    09/24/2022
    P68 RNA Helicase (DDX5) Required for the Formation of Various Specific and Mature miRNA Active RISC Complexes.

    P68 RNA Helicase (DDX5) Required for the Formation of Various Specific and Mature miRNA Active RISC Complexes.
    Kokolo M, Bach-Elias M., Free PMC Article

    08/27/2022
    Knockdown of KRAB domain-associated protein 1 suppresses the proliferation, migration and invasion of thyroid cancer cells by regulating P68/DEAD box protein 5.

    Knockdown of KRAB domain-associated protein 1 suppresses the proliferation, migration and invasion of thyroid cancer cells by regulating P68/DEAD box protein 5.
    Lan H, Lin C, Yuan H., Free PMC Article

    05/28/2022
    RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes.

    RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes.
    Sun J, Wu G, Pastor F, Rahman N, Wang WH, Zhang Z, Merle P, Hui L, Salvetti A, Durantel D, Yang D, Andrisani O., Free PMC Article

    04/16/2022
    Thrap3 promotes R-loop resolution via interaction with methylated DDX5.

    Thrap3 promotes R-loop resolution via interaction with methylated DDX5.
    Kang HJ, Eom HJ, Kim H, Myung K, Kwon HM, Choi JH., Free PMC Article

    04/9/2022
    The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2.

    The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2.
    Suthapot P, Xiao T, Felsenfeld G, Hongeng S, Wongtrakoongate P.

    02/19/2022
    Wnt/beta-catenin signaling and p68 conjointly regulate CHIP in colorectal carcinoma.

    Wnt/β-catenin signaling and p68 conjointly regulate CHIP in colorectal carcinoma.
    Kal S, Chakraborty S, Karmakar S, Ghosh MK.

    02/19/2022
    Silencing of Long Non-Coding RNA FGD5-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer by Regulating the miR-493-5p/DDX5 Axis.

    Silencing of Long Non-Coding RNA FGD5-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer by Regulating the miR-493-5p/DDX5 Axis.
    Cui F, Luo P, Bai Y, Meng J., Free PMC Article

    11/27/2021
    Low expression of DDX5 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma.

    Low expression of DDX5 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma.
    Morimachi M, Hirabayashi K, Takanashi Y, Kawanishi A, Saika T, Ueyama Y, Nakagohri T, Nakamura N, Suzuki H, Kagawa T.

    11/13/2021
    Molecular Insights into the Recruiting Between UCP2 and DDX5/UBAP2L in the Metabolic Plasticity of Non-Small-Cell Lung Cancer.

    Molecular Insights into the Recruiting Between UCP2 and DDX5/UBAP2L in the Metabolic Plasticity of Non-Small-Cell Lung Cancer.
    Yang Z, Li G, Zhao Y, Zhang L, Yuan X, Meng L, Liu H, Han Y, Jia L, Zhang S.

    10/23/2021
    BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repairdouble dagger.

    BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair‡.
    Sessa G, Gómez-González B, Silva S, Pérez-Calero C, Beaurepere R, Barroso S, Martineau S, Martin C, Ehlén Å, Martínez JS, Lombard B, Loew D, Vagner S, Aguilera A, Carreira A., Free PMC Article

    10/23/2021
    The RNA helicase DDX5 promotes viral infection via regulating N6-methyladenosine levels on the DHX58 and NFkappaB transcripts to dampen antiviral innate immunity.

    The RNA helicase DDX5 promotes viral infection via regulating N6-methyladenosine levels on the DHX58 and NFκB transcripts to dampen antiviral innate immunity.
    Xu J, Cai Y, Ma Z, Jiang B, Liu W, Cheng J, Guo N, Wang Z, Sealy JE, Song C, Wang X, Li Y., Free PMC Article

    08/14/2021
    LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-kappaB activity, promoting tumorigenesis.

    LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis.
    Li Y, Liu X, Cui X, Tan Y, Wang Q, Wang Y, Xu C, Fang C, Kang C., Free PMC Article

    07/31/2021
    MSC-AS1 induced cell growth and inflammatory mediators secretion through sponging miR-142-5p/DDX5 in gastric carcinoma.

    MSC-AS1 induced cell growth and inflammatory mediators secretion through sponging miR-142-5p/DDX5 in gastric carcinoma.
    Liu Y, Li L, Wu X, Qi H, Gao Y, Li Y, Chen D., Free PMC Article

    07/24/2021
    Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution.

    Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution.
    Villarreal OD, Mersaoui SY, Yu Z, Masson JY, Richard S., Free PMC Article

    07/17/2021
    Circ-XPR1 promotes osteosarcoma proliferation through regulating the miR-214-5p/DDX5 axis.

    Circ-XPR1 promotes osteosarcoma proliferation through regulating the miR-214-5p/DDX5 axis.
    Mao X, Guo S, Gao L, Li G.

    07/3/2021
    Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.

    Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.
    Mani SKK, Yan B, Cui Z, Sun J, Utturkar S, Foca A, Fares N, Durantel D, Lanman N, Merle P, Kazemian M, Andrisani O., Free PMC Article

    06/5/2021
    RNA helicase p68 inhibits the transcription and post-transcription of Pkd1 in ADPKD.

    RNA helicase p68 inhibits the transcription and post-transcription of Pkd1 in ADPKD.
    Zhang L, Li LX, Zhou JX, Harris PC, Calvet JP, Li X., Free PMC Article

    05/8/2021
    firstprevious page of 5 nextlast