| Human beta-defensin 2: a connection between infections and allergic skin diseases. | Human β-defensin 2: a connection between infections and allergic skin diseases.
Štrajtenberger M, Stipić-Marković A, Barac E, Artuković M, Lugović-Mihić L. | 10/3/2024 |
| Identification of human host factors required for beta-defensin-2 expression in intestinal epithelial cells upon a bacterial challenge. | Identification of human host factors required for beta-defensin-2 expression in intestinal epithelial cells upon a bacterial challenge.
Wozniak W, Sechet E, Kwon YJ, Aulner N, Navarro L, Sperandio B., Free PMC Article | 07/26/2024 |
| Salivary Th17 cytokine, human beta-defensin 1-3, and salivary scavenger and agglutinin levels in Crohn's disease. | Salivary Th17 cytokine, human β-defensin 1-3, and salivary scavenger and agglutinin levels in Crohn's disease.
Gürsoy UK, Gürsoy M, Loimaranta V, Rautava J., Free PMC Article | 01/29/2024 |
| Molecular Dynamics Simulations on Spike Protein Mutants Binding with Human beta Defensin Type 2. | Molecular Dynamics Simulations on Spike Protein Mutants Binding with Human β Defensin Type 2.
Zhang L, Li J. | 01/26/2024 |
| beta-defensin 2 protects against Escherichia coli-induced acute urinary tract infection by downregulating beta-catenin. | β-defensin 2 protects against Escherichia coli-induced acute urinary tract infection by downregulating β-catenin.
Chen B. | 01/3/2024 |
| Therapeutic modalities of human beta defensin-2 with prospective significance in diabetic wound treatment. | Therapeutic modalities of human β defensin-2 with prospective significance in diabetic wound treatment.
Yele V, Sanapalli BK. | 06/2/2023 |
| Human beta-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. | Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling.
Rückert T, Andrieux G, Boerries M, Hanke-Müller K, Woessner NM, Doetsch S, Schell C, Aumann K, Kolter J, Schmitt-Graeff A, Schiff M, Braun LM, Haring E, Kissel S, Siranosian BA, Bhatt AS, Nordkild P, Wehkamp J, Jensen BAH, Minguet S, Duyster J, Zeiser R, Köhler N. | 01/14/2023 |
| Antimicrobial peptide human beta-defensin-2 improves in vitro cellular viability and reduces pro-inflammatory effects induced by enteroinvasive Escherichia coli in Caco-2 cells by inhibiting invasion and virulence factors' expression. | Antimicrobial peptide human β-defensin-2 improves in vitro cellular viability and reduces pro-inflammatory effects induced by enteroinvasive Escherichia coli in Caco-2 cells by inhibiting invasion and virulence factors' expression.
Fusco A, Savio V, Perfetto B, Mattina R, Donnarumma G., Free PMC Article | 11/5/2022 |
| Cervicovaginal levels of human beta defensins during bacterial vaginosis. | Cervicovaginal levels of human beta defensins during bacterial vaginosis.
Noda-Nicolau NM, Silva MC, Bento GFC, Ferreira JSB, Novak J, Morales JAP, Tronco JA, Bolpetti AN, Pinto GVS, Polettini J, Marconi C, Silva MGD., Free PMC Article | 01/8/2022 |
| Human beta-Defensin 2 and Its Postulated Role in Modulation of the Immune Response. | Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response.
Cieślik M, Bagińska N, Górski A, Jończyk-Matysiak E., Free PMC Article | 12/25/2021 |
| Human beta defensin levels and vaginal microbiome composition in post-menopausal women diagnosed with lichen sclerosus. | Human beta defensin levels and vaginal microbiome composition in post-menopausal women diagnosed with lichen sclerosus.
Brunner A, Medvecz M, Makra N, Sárdy M, Komka K, Gugolya M, Szabó D, Gajdács M, Ostorházi E., Free PMC Article | 11/22/2021 |
| Serum Human beta-Defensin 2 Is Increased in Angioedema Accompanying Chronic Spontaneous Urticaria. | Serum Human β-Defensin 2 Is Increased in Angioedema Accompanying Chronic Spontaneous Urticaria.
Tra Cao TB, Cha HY, Yang EM, Choi BY, Park HS, Ye YM. | 11/13/2021 |
| Human beta-defensins 2 and 4 are dysregulated in patients with coronavirus disease 19. | Human beta-defensins 2 and 4 are dysregulated in patients with coronavirus disease 19.
Al-Bayatee NT, Ad'hiah AH., Free PMC Article | 10/23/2021 |
| Human beta-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model. | Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model.
Borchers NS, Santos-Valente E, Toncheva AA, Wehkamp J, Franke A, Gaertner VD, Nordkild P, Genuneit J, Jensen BAH, Kabesch M., Free PMC Article | 09/25/2021 |
| Increased serum antimicrobial peptide LL-37 and HBD-2 combined with 25-hydroxyvitamin D3 deficiency in infants with pertussis. | Increased serum antimicrobial peptide LL-37 and HBD-2 combined with 25-hydroxyvitamin D3 deficiency in infants with pertussis.
Chen S, Ye W, Zheng W, Xu Z, Chen Y, Jin L. | 09/4/2021 |
| Copy number variation, gene expression and histological localization of human beta-defensin 2 in patients with adeno-tonsillar hypertrophy. | Copy number variation, gene expression and histological localization of human beta-defensin 2 in patients with adeno-tonsillar hypertrophy.
Celsi F, Zupin L, Athanasakis E, Orzan E, Grasso DL, Crovella S. | 06/19/2021 |
| Relative quantification of human betadefensins gene expression in pterygium and normal conjunctiva samples. | Relative quantification of human β‑defensins gene expression in pterygium and normal conjunctiva samples.
Abubakar SA, Isa MM, Omar N, Tan SW. | 05/15/2021 |
| Relationship Between Human beta-Defensin 2 and the Vaginal Environment. | Relationship Between Human β-Defensin 2 and the Vaginal Environment.
Kotani H, Koshizuka T, Matsubara K, Nishiyama K, Sugiyama T, Suzutani T. | 01/30/2021 |
| DEFB4A Promoter Polymorphism Is Associated with Chronic Periodontitis: A Case-Control Study. | DEFB4A Promoter Polymorphism Is Associated with Chronic Periodontitis: A Case-Control Study.
Kurt-Bayrakdar S, Ozturk A, Kara N. | 10/24/2020 |
| plasma level negatively correlated with children's age with younger children having the highest levels | Association between vitamin D, antimicrobial peptides and urinary tract infection in infants and young children.
Georgieva V, Kamolvit W, Herthelius M, Lüthje P, Brauner A, Chromek M. | 06/20/2020 |
| HBD 2 promotes CCR2-mediated Nod2 signaling, which induces production of type I IFNs and an inflammatory response, and enhances primary innate immunity leading to an effective adaptive immune response to HBD 2-conjugated antigen. | Human β-defensin 2 is involved in CCR2-mediated Nod2 signal transduction, leading to activation of the innate immune response in macrophages.
Kim J, Yang YL, Jang YS., Free PMC Article | 02/1/2020 |
| DEFB4A expression is significantly downregulated in healthy palatal mucosa of smokers | Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.
Wang Y, Anderson EP, Tatakis DN. | 11/18/2019 |
| It is a immune component extensively expressed in mucosa and epidermis, which are responsible for the first line of host defense. | Influence of chewing on expression level of human beta-defensin 2 and secretory immunoglobulin A in the epithelium.
Ishida A, Wada T, Ogami K, Ueda T, Sakurai K. | 08/10/2019 |
| These findings suggest the involvement of hBD-2 in the pathogenesis of oral lichen planus (OLP) and may, thus, be harnessed for therapeutic interventions in OLP. | Human β-Defensin 2 Expression in Oral Epithelium: Potential Therapeutic Targets in Oral Lichen Planus.
Salem A, Almahmoudi R, Hagström J, Stark H, Nordström D, Salo T, Eklund KK., Free PMC Article | 08/3/2019 |
| Clinically, vaginal-douche BD2 concentrations were reduced (p < 0.05) in women suffering recurrent urinary tract infections (rUTI), compared to age-matched healthy controls with concentrations further decreased (p < 0.05) in a TLR5(392Stop) single nucleotide polymorphism rUTI subgroup. | Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection.
Ali ASM, Mowbray C, Lanz M, Stanton A, Bowen S, Varley CL, Hilton P, Brown K, Robson W, Southgate J, Aldridge PD, Tyson-Capper A, Abraham S, Pickard RS, Hall J., Free PMC Article | 06/8/2019 |