| Lipocalin-2 aggravates blood-brain barrier dysfunction after intravenous thrombolysis by promoting endothelial cell ferroptosis via regulating the HMGB1/Nrf2/HO-1 pathway. | Lipocalin-2 aggravates blood-brain barrier dysfunction after intravenous thrombolysis by promoting endothelial cell ferroptosis via regulating the HMGB1/Nrf2/HO-1 pathway.
Liu J, Pang SY, Zhou SY, He QY, Zhao RY, Qu Y, Yang Y, Guo ZN., Free PMC Article | 10/4/2024 |
| The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2. | The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2.
Gu M, Li X, Wu R, Cheng X, Zhou S, Gu X., Free PMC Article | 02/15/2024 |
| The effect of interval training on adipokine plasmatic levels in rats with induced myocardial infarction. | The effect of interval training on adipokine plasmatic levels in rats with induced myocardial infarction.
Hosseini M, Bagheri R, Nikkar H, Baker JS, Jaime SJ, Mosayebi Z, Zouraghi MR, Wong A. | 10/8/2022 |
| Upregulation of Megalin, Cubilin, NGAL mRNA expression in kidney may represent tubular injury and apoptosis in chronic condition of rat diabetic model. | Upregulation of Megalin, Cubilin, NGAL mRNA expression in kidney may represent tubular injury and apoptosis in chronic condition of rat diabetic model.
Romi MM, Anggorowati N, Maulida DS, Suskalanggeng MWAH, Setyaningsih WAW, Sari DCR, Arfian N. | 10/23/2021 |
| Silencing of lipocalin-2 improves cardiomyocyte viability under iron overload conditions via decreasing mitochondrial dysfunction and apoptosis. | Silencing of lipocalin-2 improves cardiomyocyte viability under iron overload conditions via decreasing mitochondrial dysfunction and apoptosis.
Kumfu S, Siri-Angkul N, Chattipakorn SC, Chattipakorn N. | 10/16/2021 |
| Effect of Sleeve Gastrectomy on Glycometabolism via Forkhead Box O1 (FoxO1)/Lipocalin-2 (LCN2) Pathway. | Effect of Sleeve Gastrectomy on Glycometabolism via Forkhead Box O1 (FoxO1)/Lipocalin-2 (LCN2) Pathway.
Liu Z, Sun F, Liu Z, Wang X, Jin M, Mao J, Wu Q, Yan S, Xu K, Wang K, Hu S., Free PMC Article | 05/29/2021 |
| The gonadal expression pattern of lipocalin2 and 24p3 receptor is modified in the gonads of the offspring of obese rats. | The gonadal expression pattern of lipocalin‑2 and 24p3 receptor is modified in the gonads of the offspring of obese rats.
De La Chesnaye E, Manuel-Apolinar L, Damasio L, Castrejón E, López-Ballesteros R, Revilla-Monsalve MC, Méndez JP., Free PMC Article | 05/8/2021 |
| Prediction Value of Serum NGAL in the Diagnosis and Prognosis of Experimental Acute and Chronic Kidney Injuries. | Prediction Value of Serum NGAL in the Diagnosis and Prognosis of Experimental Acute and Chronic Kidney Injuries.
Wang W, Li Z, Chen Y, Wu H, Zhang S, Chen X., Free PMC Article | 04/17/2021 |
| Time-dependent hemeoxygenase-1, lipocalin-2 and ferritin induction after non-contusion traumatic brain injury. | Time-dependent hemeoxygenase-1, lipocalin-2 and ferritin induction after non-contusion traumatic brain injury.
Russell NH, Black RT, Lee NN, Doperalski AE, Reeves TM, Phillips LL. | 10/24/2020 |
| Our findings suggest that elevated LCN2 in the blood after ischemic stroke might affect endothelial function, in part by reducing damage to endothelial junctional proteins and maintain blood-brain barrier integrity. | Effects of lipocalin-2 on brain endothelial adhesion and permeability.
Du Y, Li W, Lin L, Lo EH, Xing C., Free PMC Article | 02/22/2020 |
| NGAL can directly affect cardiomyocytes and cause cardiomyocyte deteriorated hypoxia injury through inhibiting integrin ss3 signaling. | Neutrophil Gelatinase-Associated Lipocalin2 Exaggerates Cardiomyocyte Hypoxia Injury by Inhibiting Integrin β3 Signaling.
Gu Y, Geng J, Xu Z, Chen Y, Zhang XW., Free PMC Article | 02/15/2020 |
| glomerular collagen deposition and increased lipocalin-2 expression were the early signs of kidney injury. | Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats.
Bukosza EN, Kaucsár T, Godó M, Lajtár E, Tod P, Koncsos G, Varga ZV, Baranyai T, Nguyen MT, Schachner H, Sőti C, Ferdinandy P, Giricz Z, Szénási G, Hamar P., Free PMC Article | 01/25/2020 |
| Expression of NGAL was significantly increased in the kidney tubules following endotoxin-induced renal tubular cell damage. | NGAL protects against endotoxin-induced renal tubular cell damage by suppressing apoptosis.
Han M, Li Y, Wen D, Liu M, Ma Y, Cong B., Free PMC Article | 08/3/2019 |
| Secreted LCN2 might have an influence on peripheral organ functions. | Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke.
Ranjbar Taklimie F, Gasterich N, Scheld M, Weiskirchen R, Beyer C, Clarner T, Zendedel A., Free PMC Article | 06/29/2019 |
| macrophage-secreted Lcn-2 crucial in rescuing epithelial cells from cell cycle arrest and in promoting epithelial proliferation | Lipocalin-2 abrogates epithelial cell cycle arrest by PPARγ inhibition.
Jung M, Brüne B, von Knethen A, Guiteras R, Cruzado JM, Hotter G, Sola A. | 06/15/2019 |
| Findings suggested that tissue neutrophil gelatinase-associated lipocalin expression and M2 macrophage markers are promising markers that show severity of kidney fibrosis. | Persistent expression of neutrophil gelatinase-associated lipocalin and M2 macrophage markers and chronic fibrosis after acute kidney injury.
Saito H, Tanaka T, Tanaka S, Higashijima Y, Yamaguchi J, Sugahara M, Ito M, Uchida L, Hasegawa S, Wakashima T, Fukui K, Nangaku M., Free PMC Article | 06/15/2019 |
| Light-induced LCN2 is a proapoptotic factor in the retina, and LCN2 knockdown protects photoreceptors from apoptosis by inhibiting ROS production and Bim expression. | Light-Induced Lipocalin 2 Facilitates Cellular Apoptosis by Positively Regulating Reactive Oxygen Species/Bim Signaling in Retinal Degeneration.
Tang W, Ma J, Gu R, Lei B, Ding X, Xu G. | 05/25/2019 |
| Lcn2-R upregulation and Lcn2 downregulation via Wnt/beta-catenin may promote adaptive osmotolerant survival of IMCD cells | Tonicity inversely modulates lipocalin-2 (Lcn2/24p3/NGAL) receptor (SLC22A17) and Lcn2 expression via Wnt/β-catenin signaling in renal inner medullary collecting duct cells: implications for cell fate and bacterial infection.
Betten R, Scharner B, Probst S, Edemir B, Wolff NA, Langelueddecke C, Lee WK, Thévenod F., Free PMC Article | 05/18/2019 |
| Cancer cachexia induced increased levels of aldosterone and NGAL, contributing to worsening cardiac damage in cancer cachexia-induced cardiomyopathy. | Cardiac expression of neutrophil gelatinase-associated lipocalin in a model of cancer cachexia-induced cardiomyopathy.
Musolino V, Palus S, Latouche C, Gliozzi M, Bosco F, Scarano F, Nucera S, Carresi C, Scicchitano M, von Haehling S, Jaisser F, Hasenfuss G, Anker SD, Mollace V, Springer J., Free PMC Article | 03/16/2019 |
| NGAL might be related to attenuated tubular epithelial cell damage via adjusting autophagy. | Neutrophil Gelatinase-Associated Lipocalin Attenuates Ischemia/Reperfusion Injury in an In Vitro Model via Autophagy Activation.
Yan C, Yuanjie T, Zhengqun X, Jiayan C, Kongdan L., Free PMC Article | 08/18/2018 |
| The results showed that remote limb preconditioning could decrease the expression of LCN2 protein, but having no obvious effects on its receptor except the time point of 72h after cerebral ischemia. | Downregulation of lipocalin-2 and Bim expression after remote limb preconditioning in the ischemic rat brain.
Liu M, Chen J, Zhang S, Ren C. | 08/11/2018 |
| High LCN2 expression is associated with stress-induced mitochondrial dysfunction and heart failure. | Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.
Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G., Free PMC Article | 07/28/2018 |
| This study is to investigate the level of Neutrophil gelatinase-associated lipocalin (NGAL) and autophagy status during renal Ischemia/reperfusion injury. | NGAL attenuates renal ischemia/reperfusion injury through autophagy activation and apoptosis inhibition in rats.
Zhang YL, Qiao SK, Wang RY, Guo XN. | 06/9/2018 |
| Urinary osteopontin and neutrophil gelatinase associated lipocalin can be used in the detection of drug-induced acute kidney injury. | Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury.
Phillips JA, Holder DJ, Ennulat D, Gautier JC, Sauer JM, Yang Y, McDuffie E, Sonee M, Gu YZ, Troth SP, Lynch K, Hamlin D, Peters DG, Brees D, Walker EG. | 01/20/2018 |
| This study demonstrated that Neutrophil gelatinase-associated lipocalin and microglial activity are associated with distinct postoperative behavioral changes in rats. | Neutrophil gelatinase-associated lipocalin and microglial activity are associated with distinct postoperative behavioral changes in rats.
Gouweleeuw L, Hovens IB, van Leeuwen BL, Schoemaker RG. | 12/23/2017 |