| Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. | Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch.
Gretarsson KH, Abini-Agbomson S, Gloor SL, Weinberg DN, McCuiston JL, Kumary VUS, Hickman AR, Sahu V, Lee R, Xu X, Lipieta N, Flashner S, Adeleke OA, Popova IK, Taylor HF, Noll K, Windham CL, Maryanski DN, Venters BJ, Nakagawa H, Keogh MC, Armache KJ, Lu C., Free PMC Article | 08/29/2024 |
| [Research progress on DNMT3A gene expression in Acute myeloid leukemia]. | [Research progress on DNMT3A gene expression in Acute myeloid leukemia].
Zhou J, Wu T, Liu W. | 08/16/2024 |
| Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss. | Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss.
Wang H, Divaris K, Pan B, Li X, Lim JH, Saha G, Barovic M, Giannakou D, Korostoff JM, Bing Y, Sen S, Moss K, Wu D, Beck JD, Ballantyne CM, Natarajan P, North KE, Netea MG, Chavakis T, Hajishengallis G., Free PMC Article | 08/1/2024 |
| [Relationship between DTA Mutations and Thromboembolism in Patients with Myeloproliferative Neoplasms]. | [Relationship between DTA Mutations and Thromboembolism in Patients with Myeloproliferative Neoplasms].
Wang M, Zhao HY, Li DQ, Chen P. | 07/16/2024 |
| Loss of Dnmt3a increases self-renewal and resistance to pegIFN-alpha in JAK2-V617F-positive myeloproliferative neoplasms. | Loss of Dnmt3a increases self-renewal and resistance to pegIFN-α in JAK2-V617F-positive myeloproliferative neoplasms.
Usart M, Stetka J, Luque Paz D, Hansen N, Kimmerlin Q, Almeida Fonseca T, Lock M, Kubovcakova L, Karjalainen R, Hao-Shen H, Börsch A, El Taher A, Schulz J, Leroux JC, Dirnhofer S, Skoda RC., Free PMC Article | 06/26/2024 |
| DNA methyltransferase 3A induces the occurrence of oral submucous fibrosis by promoting the methylation of the von Hippel-Lindau. | DNA methyltransferase 3A induces the occurrence of oral submucous fibrosis by promoting the methylation of the von Hippel-Lindau.
Kuang H, Yang L, Li Z, Wang J, Zheng K, Mei J, Sun H, Huang Y, Yang C, Luo W. | 06/13/2024 |
| DNMT3A Cooperates with YAP/TAZ to Drive Gallbladder Cancer Metastasis. | DNMT3A Cooperates with YAP/TAZ to Drive Gallbladder Cancer Metastasis.
Xu S, Yuan Z, Jiang C, Chen W, Li Q, Chen T., Free PMC Article | 05/7/2024 |
| Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. | Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Lu J, Guo Y, Yin J, Chen J, Wang Y, Wang GG, Song J., Free PMC Article | 04/26/2024 |
| An updated meta-analysis investigating the association between DNMTs gene polymorphism andgastric cancer risk. | An updated meta-analysis investigating the association between DNMTs gene polymorphism andgastric cancer risk.
Zhang YL, Wang YW, He MJ, Chang JL., Free PMC Article | 04/24/2024 |
| Unveiling the impact of DNA methylation machinery: Dnmt1 and Dnmt3a in orchestrating oocyte development and cellular homeostasis. | Unveiling the impact of DNA methylation machinery: Dnmt1 and Dnmt3a in orchestrating oocyte development and cellular homeostasis.
Uysal F, Sukur G, Bozdemir N, Cinar O. | 04/23/2024 |
| Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study. | Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study.
Ahn HJ, An HY, Ryu G, Lim J, Sun C, Song H, Choi SY, Lee H, Maurer T, Nachun D, Kwon S, Lee SR, Lip GYH, Oh S, Jaiswal S, Koh Y, Choi EK. | 04/17/2024 |
| From molecular pathogenesis to therapy: Unraveling non-coding RNAs/DNMT3A axis in human cancers. | From molecular pathogenesis to therapy: Unraveling non-coding RNAs/DNMT3A axis in human cancers.
Huang C, Aghaei-Zarch SM. | 03/28/2024 |
| DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts. | DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts.
Shumliakivska M, Luxán G, Hemmerling I, Scheller M, Li X, Müller-Tidow C, Schuhmacher B, Sun Z, Dendorfer A, Debes A, Glaser SF, Muhly-Reinholz M, Kirschbaum K, Hoffmann J, Nagel E, Puntmann VO, Cremer S, Leuschner F, Abplanalp WT, John D, Zeiher AM, Dimmeler S., Free PMC Article | 02/8/2024 |
| DNA methyltransferase 3a-induced hypermethylation of the fructose-1,6-bisphosphatase-2 promoter contributes to gastric carcinogenesis. | DNA methyltransferase 3a-induced hypermethylation of the fructose-1,6-bisphosphatase-2 promoter contributes to gastric carcinogenesis.
Huang Y, Lu H, Li H. | 01/10/2024 |
| miR-4270 suppresses hepatocellular carcinoma progression by inhibiting DNMT3A-mediated methylation of HGFAC promoter. | miR-4270 suppresses hepatocellular carcinoma progression by inhibiting DNMT3A-mediated methylation of HGFAC promoter.
Zou Q, Cao S., Free PMC Article | 12/18/2023 |
| Methylation signatures in clinically variable syndromic disorders: a familial DNMT3A variant in two adults with Tatton-Brown-Rahman syndrome. | Methylation signatures in clinically variable syndromic disorders: a familial DNMT3A variant in two adults with Tatton-Brown-Rahman syndrome.
Kumps C, D'haenens E, Kerkhof J, McConkey H, Alders M, Sadikovic B, Vanakker OM., | 12/5/2023 |
| Clinical features and prognostic significance of DNMT3A, FLT3, and NPM1 mutations in de novo acute myeloid leukemia patients. | Clinical features and prognostic significance of DNMT3A, FLT3, and NPM1 mutations in de novo acute myeloid leukemia patients.
Chen M, Zeng Z, Li X, Qin W, Cai X, Chen S, Lu X. | 11/20/2023 |
| High expression of DNMT3A and DNMT3B regulatory factors of TGFB in non-neoplastic liver tissues of HCC. | High expression of DNMT3A and DNMT3B regulatory factors of TGFB in non-neoplastic liver tissues of HCC.
Hu S, Luo X, Qian J, Hou Y, Shi W. | 11/6/2023 |
| Identification of Cell Type-Specific Effects of DNMT3A Mutations on Relapse in Acute Myeloid Leukemia. | Identification of Cell Type-Specific Effects of DNMT3A Mutations on Relapse in Acute Myeloid Leukemia.
Bae SG, Kim HJ, Kim MY, Kim DDH, Shin SI, Ahn JS, Park J., Free PMC Article | 10/30/2023 |
| Clonal hematopoiesis with DNMT3A mutation is associated with lower white matter hyperintensity volume. | Clonal hematopoiesis with DNMT3A mutation is associated with lower white matter hyperintensity volume.
Lee WJ, Jung KH, Song H, Lee H, Park HE, Koh Y, Choi SY, Park KI., Free PMC Article | 08/11/2023 |
| DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming. | DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming.
Yang X, Wang X, Yang Y, Li Z, Chen Y, Shang S, Wang Y., Free PMC Article | 07/25/2023 |
| Familial Clonal Hematopoiesis in a Long Telomere Syndrome. | Familial Clonal Hematopoiesis in a Long Telomere Syndrome.
DeBoy EA, Tassia MG, Schratz KE, Yan SM, Cosner ZL, McNally EJ, Gable DL, Xiang Z, Lombard DB, Antonarakis ES, Gocke CD, McCoy RC, Armanios M., Free PMC Article | 07/4/2023 |
| The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia. | The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia.
Chen X, Tian C, Hao Z, Pan L, Hong M, Wei W, Muyey DM, Wang H, Chen X., Free PMC Article | 06/2/2023 |
| Hepatitis B virus X protein induces p16 gene promoter methylation through upregulation of DNA methylation transferases DNMT1 and DNMT3A. | Hepatitis B virus X protein induces p16 gene promoter methylation through upregulation of DNA methylation transferases DNMT1 and DNMT3A.
Gan W, Kang Y, Wu Y, Zhu J, Chen Y, Kuang J, Li J, Yang L. | 05/30/2023 |
| The R736H cancer mutation in DNMT3A modulates the properties of the FF-subunit interface. | The R736H cancer mutation in DNMT3A modulates the properties of the FF-subunit interface.
Kunert S, Emperle M, Adam S, Bräcker J, Brockmeyer J, Rajavelu A, Jeltsch A. | 05/30/2023 |