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    DPP4 dipeptidyl peptidase 4 [ Homo sapiens (human) ]

    Gene ID: 1803, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exploring the conformational dynamics and key amino acids in the CD26-caveolin-1 interaction and potential therapeutic interventions.

    Exploring the conformational dynamics and key amino acids in the CD26-caveolin-1 interaction and potential therapeutic interventions.
    Hu X, Jiang C, Gu Y, Xue X., Free PMC Article

    09/17/2024
    Neuro-molecular perspectives on long COVID-19 impacted cerebrovascular diseases - a role for dipeptidyl peptidase IV.

    Neuro-molecular perspectives on long COVID-19 impacted cerebrovascular diseases - a role for dipeptidyl peptidase IV.
    Wesley UV, Dempsey RJ.

    08/30/2024
    Dipeptidyl peptidase 4 interacts with porcine coronavirus PHEV spikes and mediates host range expansion.

    Dipeptidyl peptidase 4 interacts with porcine coronavirus PHEV spikes and mediates host range expansion.
    Shi J, Hu S, Wei H, Zhang L, Lan Y, Guan J, Zhao K, Gao F, He W, Li Z., Free PMC Article

    08/22/2024
    Interleukin 13-Induced Inflammation Increases DPP4 Abundance but Does Not Enhance Middle East Respiratory Syndrome Coronavirus Replication in Airway Epithelia.

    Interleukin 13-Induced Inflammation Increases DPP4 Abundance but Does Not Enhance Middle East Respiratory Syndrome Coronavirus Replication in Airway Epithelia.
    Li K, Bartlett JA, Wohlford-Lenane CL, Xue B, Thurman AL, Gallagher TM, Pezzulo AA, McCray PB Jr., Free PMC Article

    07/31/2024
    Increased Thyroid DPP4 Expression Is Associated With Inflammatory Process in Patients With Hashimoto Thyroiditis.

    Increased Thyroid DPP4 Expression Is Associated With Inflammatory Process in Patients With Hashimoto Thyroiditis.
    Wen X, Chang X, He X, Cai Q, Wang G, Liu J., Free PMC Article

    07/17/2024
    Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection.

    Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection.
    Deinhardt-Emmer S, Deshpande S, Kitazawa K, Herman AB, Bons J, Rose JP, Kumar PA, Anerillas C, Neri F, Ciotlos S, Perez K, Köse-Vogel N, Häder A, Abdelmohsen K, Löffler B, Gorospe M, Desprez PY, Melov S, Furman D, Schilling B, Campisi J., Free PMC Article

    06/10/2024
    Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme.

    Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme.
    Gnoth K, Bär JW, Rosche F, Rahfeld JU, Demuth HU., Free PMC Article

    04/24/2024
    A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes.

    A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes.
    Kotnala S, Dhasmana A, Dhasmana S, Haque S, Yallapu MM, Tripathi MK, Jaggi M, Chauhan SC.,

    03/21/2024
    Association of DPP-4 Concentrations with the Occurrence of Gestational Diabetes Mellitus and Excessive Gestational Weight Gain.

    Association of DPP-4 Concentrations with the Occurrence of Gestational Diabetes Mellitus and Excessive Gestational Weight Gain.
    Niebrzydowska-Tatus M, Pełech A, Bień K, Mekler J, Santiago M, Kimber-Trojnar Ż, Trojnar M., Free PMC Article

    02/28/2024
    m6A reader IGF2BP2 promotes lymphatic metastasis by stabilizing DPP4 in papillary thyroid carcinoma.

    m6A reader IGF2BP2 promotes lymphatic metastasis by stabilizing DPP4 in papillary thyroid carcinoma.
    Wang W, Ding Y, Zhao Y, Li X.

    02/22/2024
    Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population.

    Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population.
    Hubáček JA, Philipp T, Adámková V, Májek O, Dlouhá D, Dušek L.

    02/7/2024
    DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-alpha5beta1/FAK/AKT signaling.

    DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
    Liu C, Xu J, Fan J, Liu C, Xie W, Kong H.

    02/4/2024
    Diabetic individuals with COVID-19 exhibit reduced efficacy of gliptins in inhibiting dipeptidyl peptidase 4 (DPP4). A suggested explanation for increased COVID-19 susceptibility in patients with type 2 diabetes mellitus (T2DM).

    Diabetic individuals with COVID-19 exhibit reduced efficacy of gliptins in inhibiting dipeptidyl peptidase 4 (DPP4). A suggested explanation for increased COVID-19 susceptibility in patients with type 2 diabetes mellitus (T2DM).
    Mora-Rodríguez JM, Sánchez BG, Bort A, Díaz-Yuste A, Ballester-González R, Arrieta F, Sebastián-Martín A, Díaz-Laviada I.

    01/3/2024
    VEGFR and DPP-IV as Markers of Severe COVID-19 and Predictors of ICU Admission.

    VEGFR and DPP-IV as Markers of Severe COVID-19 and Predictors of ICU Admission.
    Pius-Sadowska E, Kulig P, Niedźwiedź A, Baumert B, Łuczkowska K, Rogińska D, Sobuś A, Ulańczyk Z, Kawa M, Paczkowska E, Parczewski M, Machalińska A, Machaliński B., Free PMC Article

    12/20/2023
    The Activity of Adenosine Deaminase and Dipeptidyl Peptidase IV in Children With Attention Deficit Hyperactivity Disorder.

    The Activity of Adenosine Deaminase and Dipeptidyl Peptidase IV in Children With Attention Deficit Hyperactivity Disorder.
    Naralan YS, Doğan Ö, Elgün S, Öztop DB, Kılıç BG.

    11/30/2023
    Differential expression of carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and dipeptidyl peptidase-4 (DPP4) with detection of Middle East respiratory syndrome-coronavirus in peripheral blood.

    Differential expression of carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and dipeptidyl peptidase-4 (DPP4) with detection of Middle East respiratory syndrome-coronavirus in peripheral blood.
    Alhetheel A, Albarrag A, Shakoor Z, Somily A, Barry M, Altalhi H, Bakhrebah M, Nassar M, Alfageeh M, Assiri A, Alfaraj S, Memish ZA., Free PMC Article

    11/15/2023
    Effects of dipeptidyl peptidase 4 inhibition on the endothelial control of the vascular tone.

    Effects of dipeptidyl peptidase 4 inhibition on the endothelial control of the vascular tone.
    Ribeiro-Silva JC, Marques VB, Dos Santos L.

    10/11/2023
    Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells.

    Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells.
    Wang C, Nistala R, Cao M, Pan Y, Behrens M, Doll D, Hammer RD, Nistala P, Chang HM, Yeh ETH, Kang X., Free PMC Article

    10/5/2023
    Genetic variants of dipeptidyl peptidase IV are linked to the clinicopathologic development of prostate cancer.

    Genetic variants of dipeptidyl peptidase IV are linked to the clinicopathologic development of prostate cancer.
    Wen YC, Lin CY, Hsiao CH, Wang SS, Huang HC, Lin YW, Ho KH, Chang LC, Yang SF, Chien MH., Free PMC Article

    09/1/2023
    Association of Dipeptidylpeptidase 4 (CD26) With Chondrocyte Senescence and Radiographic Progression in Knee Osteoarthritis.

    Association of Dipeptidylpeptidase 4 (CD26) With Chondrocyte Senescence and Radiographic Progression in Knee Osteoarthritis.
    Chen YH, Zhang X, Chou CH, Hsueh MF, Attarian D, Li YJ, Kraus VB., Free PMC Article

    06/29/2023
    DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.

    DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
    Strine MS, Cai WL, Wei J, Alfajaro MM, Filler RB, Biering SB, Sarnik S, Chow RD, Patil A, Cervantes KS, Collings CK, DeWeirdt PC, Hanna RE, Schofield K, Hulme C, Konermann S, Doench JG, Hsu PD, Kadoch C, Yan Q, Wilen CB., Free PMC Article

    06/22/2023
    The Combination of Natural Molecules Naringenin, Hesperetin, Curcumin, Polydatin and Quercetin Synergistically Decreases SEMA3E Expression Levels and DPPIV Activity in In Vitro Models of Insulin Resistance.

    The Combination of Natural Molecules Naringenin, Hesperetin, Curcumin, Polydatin and Quercetin Synergistically Decreases SEMA3E Expression Levels and DPPIV Activity in In Vitro Models of Insulin Resistance.
    Scarpa ES, Giordani C, Antonelli A, Petrelli M, Balercia G, Silvetti F, Pieroni A, Sabbatinelli J, Rippo MR, Olivieri F, Matacchione G., Free PMC Article

    06/7/2023
    Dipeptidyl peptidase 4 as a potential serum biomarker for disease activity and treatment response in rheumatoid arthritis.

    Dipeptidyl peptidase 4 as a potential serum biomarker for disease activity and treatment response in rheumatoid arthritis.
    Yu J, Hu C, Dai Z, Xu J, Zhang L, Deng H, Xu Y, Zhao L, Li M, Liu L, Zhang M, Huang J, Wu L, Chen G.

    06/1/2023
    HMGCL-induced beta-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.

    HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
    Cui X, Yun X, Sun M, Li R, Lyu X, Lao Y, Qin X, Yu W., Free PMC Article

    04/26/2023
    Distinct T cell subsets in adipose tissue are associated with obesity.

    Distinct T cell subsets in adipose tissue are associated with obesity.
    Haugstøyl ME, Cornillet M, Strand K, Stiglund N, Sun D, Lawrence-Archer L, Hjellestad ID, Sparrelid E, Busch C, Hjelmesaeth J, Hertel JK, Ponzetta A, Mellgren G, Fernø J, Björkström NK., Free PMC Article

    02/14/2023
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