| ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort. | ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort.
Kruk B, Liebe R, Weber SN, Milkiewicz P, Krawczyk M. | 08/22/2024 |
| A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression. | A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression.
Li Y, Li Z, Chen R, Lian M, Wang H, Wei Y, You Z, Zhang J, Li B, Li Y, Huang B, Chen Y, Liu Q, Lyu Z, Liang X, Miao Q, Xiao X, Wang Q, Fang J, Shi Y, Liu X, Seldin MF, Gershwin ME, Tang R, Ma X., Free PMC Article | 04/4/2023 |
| Several genetic variants associated with systemic sclerosis in a Chinese Han population. | Several genetic variants associated with systemic sclerosis in a Chinese Han population.
Liu C, Yan S, Chen H, Wu Z, Li L, Li Y. | 02/22/2023 |
| Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature. | Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature.
Shen M, Li S, Zhao Y, Liu Y, Liu Z, Huan L, Qiao Y, Wang L, Han L, Chen Z, He X., Free PMC Article | 09/3/2022 |
| ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3. | ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.
Li Y, Tang J, Li J, Du Y, Bai F, Yang L, Li X, Jin X, Wang T. | 06/11/2022 |
| MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A. | MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A.
Zhou D, Ji G, Wei G, Li Z, Yu N, Wang Y, Lin B, Zhang L, Yin Y. | 06/11/2022 |
| The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. | The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi E, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH., Free PMC Article | 03/12/2022 |
| Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis. | Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis.
Garton J, Shankar M, Chapman B, Rose K, Gaffney PM, Webb CF., Free PMC Article | 02/19/2022 |
| ARID3A regulates autophagy related gene BECN1 expression and inhibits proliferation of osteosarcoma cells. | ARID3A regulates autophagy related gene BECN1 expression and inhibits proliferation of osteosarcoma cells.
Parlayan C, Sahin Y, Altan Z, Arman K, Ikeda MA, Saadat KASM. | 01/8/2022 |
| Distinct and overlapping roles of ARID3A and ARID3B in regulating E2Fdependent transcription via direct binding to E2F target genes. | Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.
Saadat KASM, Lestari W, Pratama E, Ma T, Iseki S, Tatsumi M, Ikeda MA. | 11/6/2021 |
| ARID3A promotes the development of colorectal cancer by upregulating AURKA. | ARID3A promotes the development of colorectal cancer by upregulating AURKA.
Tang J, Yang L, Li Y, Ning X, Chaulagain A, Wang T, Wang D. | 10/2/2021 |
| Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells. | Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells.
Arman K, Saadat KASM, Igci YZ, Bozgeyik E, Ikeda MA, Cakmak EA, Arslan A. | 06/26/2021 |
| TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production. | TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production.
Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF., Free PMC Article | 03/13/2021 |
| ARID3A was verified as a direct target gene of miR-574-5p and decreased level of ARID3A forced fibroblast-to-myofibroblast differentiation of TGF-beta-induced human cardiac fibroblasts. | MiR-574-5p promotes the differentiation of human cardiac fibroblasts via regulating ARID3A.
Cui J, Qi S, Liao R, Su D, Wang Y, Xue S. | 08/1/2020 |
| The associations of ARID3a expression with increased disease severity in Systemic Lupus Erythematosus (SLE), suggest that it, or its downstream targets, may provide new therapeutic targets for SLE. [review] | New Frontiers: ARID3a in SLE.
Garton J, Barron MD, Ratliff ML, Webb CF., Free PMC Article | 06/20/2020 |
| Study provides a comprehensive list of genes and pathways regulated by ARID3A and ARID3B in ovarian cancer cells. | ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells.
Dausinas P, Pulakanti K, Rao S, Cole JM, Dahl R, Cowden Dahl KD., Free PMC Article | 05/2/2020 |
| these data identify ARID3a as a potential transcription regulator of IFNalpha-related inflammatory responses and other pathways important for systemic lupus erythematosus disease activity | ARID3a gene profiles are strongly associated with human interferon alpha production.
Ratliff ML, Garton J, Garman L, Barron MD, Georgescu C, White KA, Chakravarty E, Wren JD, Montgomery CG, James JA, Webb CF., Free PMC Article | 04/11/2020 |
| Study demonstrated that ARID3A overexpression is an independent prognostic factor for cancer-specific survival in patients with surgically resected residual rectal cancer after neoadjuvant chemoradiotherapy and plays an important role in rectal cancer. | ARID3A Positivity Correlated With Favorable Prognosis in Patients With Residual Rectal Cancer After Neoadjuvant Chemoradiotherapy.
Yoon G, Park JY, Kim HJ, Choi GS, Kim JG, Kang BW, Kang MK, Seo AN. | 06/22/2019 |
| Data indicate ARID3a(+) B cells as a type of effector B cell, and link ARID3a expression in B lymphocytes to interferon alpha (IFNa)-associated inflammatory responses in systemic lupus erythematosus (SLE). | Human effector B lymphocytes express ARID3a and secrete interferon alpha.
Ward JM, Ratliff ML, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF., Free PMC Article | 06/3/2017 |
| results suggest that appropriate regulation of ARID3a is critical for normal development of both myeloid and B lineage pathways. | The Transcription Factor ARID3a Is Important for In Vitro Differentiation of Human Hematopoietic Progenitors.
Ratliff ML, Mishra M, Frank MB, Guthridge JM, Webb CF., Free PMC Article | 05/28/2016 |
| These data reveal new functions for ARID3a in early hematopoiesis and suggest that knowledge regarding ARID3a levels in HSPCs could be informative for applications requiring transplantation of those cells. | Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells.
Ratliff ML, Ward JM, Merrill JT, James JA, Webb CF., Free PMC Article | 04/18/2015 |
| Systemic lupus erythematosus (SLE) patients had increased ARID3a+ B cells compared to healthy controls. ARID3a was not expressed in naive B cells of controls, but was abundant in SLE patients. Number of ARID3a+ B cells correlated with disease activity. | Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A.
Ward JM, Rose K, Montgomery C, Adrianto I, James JA, Merrill JT, Webb CF., Free PMC Article | 02/21/2015 |
| miR-125b can act as an oncogene in B-cell acute lymphoblastic leukemia by targeting ARID3a and mediating its repression. | B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells.
Puissegur MP, Eichner R, Quelen C, Coyaud E, Mari B, Lebrigand K, Broccardo C, Nguyen-Khac F, Bousquet M, Brousset P. | 12/22/2012 |
| These findings support the hypothesis that Epstein-Barr virus EBNA1 initiates transcription at the C promoter via interactions between multiple EBNA1 homodimers and cellular transcription such as E2F1, ARID3A and Oct-2. | E2F1, ARID3A/Bright and Oct-2 factors bind to the Epstein-Barr virus C promoter, EBNA1 and oriP, participating in long-distance promoter-enhancer interactions.
Boreström C, Forsman A, Rüetschi U, Rymo L. | 06/9/2012 |
| These results indicate both cooperative and interdependent roles for ARID3A and p53 in the transcriptional activation of p21(WAF1) in response to DNA damage. | Cooperation between ARID3A and p53 in the transcriptional activation of p21WAF1 in response to DNA damage.
Lestari W, Ichwan SJ, Otsu M, Yamada S, Iseki S, Shimizu S, Ikeda MA. | 03/17/2012 |