Cholinergic mu-opioid receptor deletion alters reward preference and aversion-resistance. | Cholinergic mu-opioid receptor deletion alters reward preference and aversion-resistance. Beane CR, Lewis DG, Bruns Vi N, Pikus KL, Durfee MH, Zegarelli RA, Perry TW, Sandoval O, Radke AK. | 10/22/2024 |
Anatomical distribution of micro-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network. | Anatomical distribution of µ-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network. Furdui A, da Silveira Scarpellini C, Montandon G. | 07/24/2024 |
Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells. | Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells. Qian C, Xin Y, Qi C, Wang H, Dong BC, Zack DJ, Blackshaw S, Hattar S, Zhou FQ, Qian J. | 03/14/2024 |
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to mu-opioidergic cell types. | Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types. Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, De Jonghe BC, Bennett FC, Bennett ML, Blendy JA, Platt ML, Creasy KT, Renthal WR, Ramakrishnan C, Deisseroth K, Corder G., Free PMC Article | 09/19/2023 |
Mu-opioid receptor alleviated ferroptosis in hepatic ischemia-reperfusion injury via the HIF-1alpha/KCNQ1OT1 axis. | Mu-opioid receptor alleviated ferroptosis in hepatic ischemia-reperfusion injury via the HIF-1α/KCNQ1OT1 axis. Zou S, Sun H, Peng Y, Liang C, Zheng C, Wang L, Yang J. | 04/15/2023 |
Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the mouse nucleus accumbens. | Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the mouse nucleus accumbens. Retzlaff CL, Rothwell PE., Free PMC Article | 09/24/2022 |
Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons. | Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons. Quirion B, Beaulieu C, Côté L, Parent JL, Gendron L., Free PMC Article | 08/13/2022 |
Novel role of the Mu-opioid receptor in pancreatic cancer: potential link between opioid use and cancer progression. | Novel role of the Mu-opioid receptor in pancreatic cancer: potential link between opioid use and cancer progression. Haque MR, Barlass U, Armstrong A, Shaikh M, Bishehsari F. | 04/30/2022 |
Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1. | Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1. Narayan A, Hunkele A, Xu J, Bassoni DL, Pasternak GW, Pan YX., Free PMC Article | 02/12/2022 |
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site. | Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site. Uprety R, Che T, Zaidi SA, Grinnell SG, Varga BR, Faouzi A, Slocum ST, Allaoa A, Varadi A, Nelson M, Bernhard SM, Kulko E, Le Rouzic V, Eans SO, Simons CA, Hunkele A, Subrath J, Pan YX, Javitch JA, McLaughlin JP, Roth BL, Pasternak GW, Katritch V, Majumdar S., Free PMC Article | 02/12/2022 |
A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes. | A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes. Robert B, Kimchi EY, Watanabe Y, Chakoma T, Jing M, Li Y, Polley DB., Free PMC Article | 01/22/2022 |
Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. | Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. He XJ, Patel J, Weiss CE, Ma X, Bloodgood BL, Banghart MR., Free PMC Article | 01/22/2022 |
mu-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. | μ-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. Gao H, Zhang Y, Li Y, Chang H, Cheng B, Li N, Yuan W, Li S, Wang Q. | 12/11/2021 |
HA-MOP knockin mice express the canonical micro-opioid receptor but lack detectable splice variants. | HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants. Fritzwanker S, Moulédous L, Mollereau C, Froment C, Burlet-Schiltz O, Effah F, Bailey A, Spetea M, Reinscheid RK, Schulz S, Kliewer A., Free PMC Article | 12/11/2021 |
mu-Opioid Receptor (Oprm1) Copy Number Influences Nucleus Accumbens Microcircuitry and Reciprocal Social Behaviors. | μ-Opioid Receptor (Oprm1) Copy Number Influences Nucleus Accumbens Microcircuitry and Reciprocal Social Behaviors. Toddes C, Lefevre EM, Brandner DD, Zugschwert L, Rothwell PE., Free PMC Article | 11/27/2021 |
micro-Opioid receptor-induced synaptic plasticity in dopamine neurons mediates the rewarding properties of anabolic androgenic steroids. | µ-Opioid receptor-induced synaptic plasticity in dopamine neurons mediates the rewarding properties of anabolic androgenic steroids. Bontempi L, Bonci A. | 10/30/2021 |
Dual mechanisms of opioid-induced respiratory depression in the inspiratory rhythm-generating network. | Dual mechanisms of opioid-induced respiratory depression in the inspiratory rhythm-generating network. Baertsch NA, Bush NE, Burgraff NJ, Ramirez JM., Free PMC Article | 10/16/2021 |
Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration. | Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration. Zhang Y, Collins D, Butelman ER, Blendy JA, Kreek MJ. | 09/25/2021 |
Loss of mu and delta opioid receptors on neurons expressing dopamine receptor D1 has no effect on reward sensitivity. | Loss of mu and delta opioid receptors on neurons expressing dopamine receptor D1 has no effect on reward sensitivity. Harda Z, Spyrka J, Jastrzębska K, Szumiec Ł, Bryksa A, Klimczak M, Polaszek M, Gołda S, Zajdel J, Misiołek K, Błasiak A, Rodriguez Parkitna J. | 08/28/2021 |
Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP. | Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP. Robinson SA, Jones AD, Brynildsen JK, Ehrlich ME, Blendy JA., Free PMC Article | 08/14/2021 |
The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception. | The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception. Sánchez-Blázquez P, Cortés-Montero E, Rodríguez-Muñoz M, Merlos M, Garzón-Niño J., Free PMC Article | 08/7/2021 |
Differential genetic risk for methamphetamine intake confers differential sensitivity to the temperature-altering effects of other addictive drugs. | Differential genetic risk for methamphetamine intake confers differential sensitivity to the temperature-altering effects of other addictive drugs. Mootz JRK, Miner NB, Phillips TJ., Free PMC Article | 07/17/2021 |
Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference. | Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference. Collins D, Zhang Y, Blendy J, Kreek MJ. | 04/24/2021 |
Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition. | Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition. Wang Z, Jiang C, Yao H, Chen O, Rahman S, Gu Y, Zhao J, Huh Y, Ji RR. | 04/24/2021 |
Morphine modulates the expression of mu-opioid receptor exon 5-associated full-length C-terminal splice variants by upregulating miR-378a-3p. | Morphine modulates the expression of mu-opioid receptor exon 5-associated full-length C-terminal splice variants by upregulating miR-378a-3p. Lu Z, Xu J, Wang Q, Pan YX., Free PMC Article | 03/27/2021 |