| Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population. | Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
Binjawhar DN, Ansari MGA, Sabico S, Hussain SD, Alenad AM, Alokail MS, Al-Masri AA, Al-Daghri NM., Free PMC Article | 04/14/2023 |
| DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases. | DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases.
Khoubai FZ, Grosset CF., Free PMC Article | 12/18/2021 |
| DUSP9 upregulation in the placenta of gestational diabetes mellitus pregnant women may promote insulin resistance, which may correlate with the occurrence of gestational diabetes. | Expression of Dual-Specificity Phosphatase 9 in Placenta and Its Relationship with Gestational Diabetes Mellitus.
Wei Q, Pu X, Zhang L, Xu Y, Duan M, Wang Y., Free PMC Article | 04/25/2020 |
| Chemotherapy increased DUSP9 expression and decreased DUSP16 expression in a HIF1-dependent manner. | Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.
Lu H, Tran L, Park Y, Chen I, Lan J, Xie Y, Semenza GL. | 08/31/2019 |
| SNP rs5945326 in DUSP9 gene may be not associated with the risk of gestational diabetes mellitus | [Association of DUSP9 gene polymorphisms with gestational diabetes mellitus].
Wang X, Zhang L, Ou G, Wei Q, Wu L, Chen Q. | 08/31/2019 |
| The results of this study, combined with previous studies, suggested that therapeutic intervention to increase the expression or activity of DUSP9 may enable the activation of anti-proliferation signals in malignant cells. | Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling.
Wu F, Lv T, Chen G, Ye H, Wu W, Li G, Zhi FC. | 03/19/2016 |
| A possible use for DUSP9 as CIMP marker. | Development of a DUSP9 methylation screening assay.
Jenner S, Wiedorn KH, Techel D. | 09/12/2015 |
| DUSP9 protein levels were markedly suppressed in severe pre-eclampsia, but not in severe IUGR. This suppression might be attributable to the prolonged hypoxic conditions found in pre-eclampsia. | Dual specificity phosphatase 9 (DUSP9) expression is down-regulated in the severe pre-eclamptic placenta.
Czikk MJ, Drewlo S, Baczyk D, Adamson SL, Kingdom J. | 09/7/2013 |
| The DUSP9 locus is a common susceptibility locus for type 2 diabetes across different ethnicities, and 6 loci identified in South Asian genome-wide association studies also have significant effect on susceptibility to Japanese type 2 diabetes. | A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population.
Fukuda H, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S., Free PMC Article | 02/23/2013 |
| decreased expression of DUSP-9 is associated with poor prognosis in ccRCC. | Decreased expression of dual-specificity phosphatase 9 is associated with poor prognosis in clear cell renal cell carcinoma.
Wu S, Wang Y, Sun L, Zhang Z, Jiang Z, Qin Z, Han H, Liu Z, Li X, Tang A, Gui Y, Cai Z, Zhou F., Free PMC Article | 02/4/2012 |
| DUSP9/MKP-4 is a bona fide target of PKA signaling and attenuation of DUSP9/MKP-4 function can mediate cross-talk between the PKA pathway and MAPK signaling through both ERK1/2 and p38alpha in vivo | Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways.
Dickinson RJ, Delavaine L, Cejudo-Marín R, Stewart G, Staples CJ, Didmon MP, Trinidad AG, Alonso A, Pulido R, Keyse SM., Free PMC Article | 01/14/2012 |
| 2.7 A resolution crystal structure of the catalytic domain of MKP-4 (MKP-4C) is presented | Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4.
Jeong DG, Yoon TS, Jung SK, Park BC, Park H, Ryu SE, Kim SJ. | 03/26/2011 |
| microtubule disruption by MKP4 provides a novel mechanism for tumor suppression by a cytosolic MKP | Microtubule disruption and tumor suppression by mitogen-activated protein kinase phosphatase 4.
Liu Y, Lagowski J, Sundholm A, Sundberg A, Kulesz-Martin M. | 01/21/2010 |