| Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7. | Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7.
Chu D, Lei L, Gu S, Liu F, Wu F. | 05/28/2024 |
| Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions. | Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions.
Neuhaus E, Rea H, Jones E, Benavidez H, Miles C, Whiting A, Johansson M, Eayrs C, Kurtz-Nelson EC, Earl R, Bernier RA, Eichler EE., Free PMC Article | 04/22/2024 |
| MicroRNA-221-3p inhibits the inflammatory response of keratinocytes by regulating the DYRK1A/STAT3 signaling pathway to promote wound healing in diabetes. | MicroRNA-221-3p inhibits the inflammatory response of keratinocytes by regulating the DYRK1A/STAT3 signaling pathway to promote wound healing in diabetes.
Hu K, Liu L, Tang S, Zhang X, Chang H, Chen W, Fan T, Zhang L, Shen B, Zhang Q., Free PMC Article | 03/28/2024 |
| Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders. | Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders.
Hogg EKJ, Findlay GM., Free PMC Article | 03/25/2024 |
| DYRK1A gene linked to heart defects in Down syndrome. | DYRK1A gene linked to heart defects in Down syndrome.
Fernández-Ruiz I. | 03/20/2024 |
| Loss of the DYRK1A Protein Kinase Results in the Reduction in Ribosomal Protein Gene Expression, Ribosome Mass and Reduced Translation. | Loss of the DYRK1A Protein Kinase Results in the Reduction in Ribosomal Protein Gene Expression, Ribosome Mass and Reduced Translation.
Di Vona C, Barba L, Ferrari R, de la Luna S., Free PMC Article | 02/12/2024 |
| DYRK1A is a multifunctional host factor that regulates coronavirus replication in a kinase-independent manner. | DYRK1A is a multifunctional host factor that regulates coronavirus replication in a kinase-independent manner.
Fu Z, Xiang Y, Fu Y, Su Z, Tan Y, Yang M, Yan Y, Baghaei Daemi H, Shi Y, Xie S, Sun L, Peng G., Free PMC Article | 01/30/2024 |
| Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis. | Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis.
Sit YT, Takasaki K, An HH, Xiao Y, Hurtz C, Gearhart PA, Zhang Z, Gadue P, French DL, Chou ST., Free PMC Article | 12/21/2023 |
| Identification of FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A. | Identification of FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A.
Miyata Y, Nishida E., Free PMC Article | 11/3/2023 |
| Characterizing the autism spectrum phenotype in DYRK1A-related syndrome. | Characterizing the autism spectrum phenotype in DYRK1A-related syndrome.
Kurtz-Nelson EC, Rea HM, Petriceks AC, Hudac CM, Wang T, Earl RK, Bernier RA, Eichler EE, Neuhaus E., | 08/30/2023 |
| Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels. | Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels.
Murray A, Gough G, Cindrić A, Vučković F, Koschut D, Borelli V, Petrović DJ, Bekavac A, Plećaš A, Hribljan V, Brunmeir R, Jurić J, Pučić-Baković M, Slana A, Deriš H, Frkatović A, Groet J, O'Brien NL, Chen HY, Yeap YJ, Delom F, Havlicek S, Gammon L, Hamburg S, Startin C, D'Souza H, Mitrečić D, Kero M, Odak L, Krušlin B, Krsnik Ž, Kostović I, Foo JN, Loh YH, Dunn NR, de la Luna S, Spector T, Barišić I, Thomas MSC, Strydom A, Franceschi C, Lauc G, Krištić J, Alić I, Nižetić D., Free PMC Article | 08/16/2023 |
| A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21. | A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21.
Bélanger F, Roussel C, Sawchyn C, St-Hilaire E, Gezzar-Dandashi S, Kimenyi Ishimwe AB, Mallette FA, Wurtele H, Drobetsky E., Free PMC Article | 08/4/2023 |
| DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner. | DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Strine MS, Cai WL, Wei J, Alfajaro MM, Filler RB, Biering SB, Sarnik S, Chow RD, Patil A, Cervantes KS, Collings CK, DeWeirdt PC, Hanna RE, Schofield K, Hulme C, Konermann S, Doench JG, Hsu PD, Kadoch C, Yan Q, Wilen CB., Free PMC Article | 06/22/2023 |
| Function and inhibition of DYRK1A: Emerging roles of treating multiple human diseases. | Function and inhibition of DYRK1A: Emerging roles of treating multiple human diseases.
Yang Y, Fan X, Liu Y, Ye D, Liu C, Yang H, Su Z, Zhang Y, Liu Y. | 05/22/2023 |
| The Conserved Transcriptional Activation Activity Identified in Dual-Specificity Tyrosine-(Y)-Phosphorylation-Regulated Kinase 1. | The Conserved Transcriptional Activation Activity Identified in Dual-Specificity Tyrosine-(Y)-Phosphorylation-Regulated Kinase 1.
Ouyang X, Wang Z, Wu B, Yang X, Dong B., Free PMC Article | 03/1/2023 |
| Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes. | Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes.
Elagib KE, Brock A, Clementelli CM, Mosoyan G, Delehanty LL, Sahu RK, Pacheco-Benichou A, Fruit C, Besson T, Morris SW, Eto K, Jobaliya C, French DL, Gadue P, Singh S, Shi X, Qin F, Cornelison R, Li H, Iancu-Rubin C, Goldfarb AN., Free PMC Article | 10/8/2022 |
| The Omnipresence of DYRK1A in Human Diseases. | The Omnipresence of DYRK1A in Human Diseases.
Deboever E, Fistrovich A, Hulme C, Dunckley T., Free PMC Article | 09/3/2022 |
| APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. | APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons.
Wu CI, Vinton EA, Pearse RV 2nd, Heo K, Aylward AJ, Hsieh YC, Bi Y, Adeleye S, Fancher S, Duong DM, Seyfried NT, Schwarz TL, Young-Pearse TL., Free PMC Article | 05/28/2022 |
| The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target. | The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target.
Rammohan M, Harris E, Bhansali RS, Zhao E, Li LS, Crispino JD., Free PMC Article | 04/16/2022 |
| Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B. | Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B.
Papenfuss M, Lützow S, Wilms G, Babendreyer A, Flaßhoff M, Kunick C, Becker W., Free PMC Article | 03/19/2022 |
| Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study. | Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study.
Shahroz MM, Sharma HK, Altamimi ASA, Alamri MA, Ali A, Ali A, Alqahtani S, Altharawi A, Alabbas AB, Alossaimi MA, Riadi Y, Firoz A, Afzal O., Free PMC Article | 03/5/2022 |
| DYRK1A activates NFATC1 to increase glioblastoma migration. | DYRK1A activates NFATC1 to increase glioblastoma migration.
Liu H, Sun Q, Chen S, Chen L, Jia W, Zhao J, Sun X., Free PMC Article | 02/26/2022 |
| Association analysis and polygenic risk score evaluation of 38 GWAS-identified Loci in a Chinese population with Parkinson's disease. | Association analysis and polygenic risk score evaluation of 38 GWAS-identified Loci in a Chinese population with Parkinson's disease.
Zheng R, Qiao S, Chen Y, Jin C, Fang Y, Lin Z, Xue N, Yan Y, Gu L, Gao T, Tian J, Yan Y, Yin X, Pu J, Zhang B. | 01/22/2022 |
| Suppression of DYRK1A/B Drives Endoplasmic Reticulum Stress-mediated Autophagic Cell Death Through Metabolic Reprogramming in Colorectal Cancer Cells. | Suppression of DYRK1A/B Drives Endoplasmic Reticulum Stress-mediated Autophagic Cell Death Through Metabolic Reprogramming in Colorectal Cancer Cells.
Hwang J, Park A, Kim C, Yu D, Byun H, Ku M, Yang J, Kim TI, Jeong KS, Kim KY, Lee H, Shin SJ. | 01/15/2022 |
| Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. | Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.
Kaltheuner IH, Anand K, Moecking J, Düster R, Wang J, Gray NS, Geyer M., Free PMC Article | 12/18/2021 |