The association of E2F1 and E2F2 single nucleotide polymorphisms with laryngeal squamous cell carcinoma pathomorphological features. | The association of E2F1 and E2F2 single nucleotide polymorphisms with laryngeal squamous cell carcinoma pathomorphological features. Jakstas T, Bartnykaite A, Padervinskis E, Vegiene A, Juozaityte E, Uloza V, Ugenskiene R., Free PMC Article | 02/23/2024 |
DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression. | DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression. Hua R, Chu Q, Guo F, Chen Q, Li M, Zhou X, Zhu Y., Free PMC Article | 01/5/2024 |
C/EBPbeta Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes. | C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes. Liu S, Wang J, Chen S, Han Z, Wu H, Chen H, Duan Y., Free PMC Article | 02/16/2023 |
Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy. | Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy. Liu TT, Yang H, Zhuo FF, Yang Z, Zhao MM, Guo Q, Liu Y, Liu D, Zeng KW, Tu PF., Free PMC Article | 01/14/2023 |
Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis. | Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis. Ye Q, Taleb SJ, Wang H, Parinandi NL, Kass DJ, Rojas M, Wang C, Ma Q, Zhao J, Zhao Y., Free PMC Article | 11/12/2022 |
Alteration of E2F2 Expression in Governing Endothelial Cell Senescence. | Alteration of E2F2 Expression in Governing Endothelial Cell Senescence. Liu H, Chen L, Xiao W, Liu J, Long C, Zhan W, Cui C, Yang L, Chen S., Free PMC Article | 10/8/2022 |
E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry. | E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry. Du K, Sun S, Jiang T, Liu T, Zuo X, Xia X, Liu X, Wang Y, Bu Y., Free PMC Article | 07/23/2022 |
E2F2 enhances the chemoresistance of pancreatic cancer to gemcitabine by regulating the cell cycle and upregulating the expression of RRM2. | E2F2 enhances the chemoresistance of pancreatic cancer to gemcitabine by regulating the cell cycle and upregulating the expression of RRM2. Liu Q, Song C, Li J, Liu M, Fu L, Jiang J, Zeng Z, Zhu H. | 07/2/2022 |
Circular RNA circE2F2 promotes malignant progression of ovarian cancer cells by upregulating the expression of E2F2 protein via binding to HuR protein. | Circular RNA circE2F2 promotes malignant progression of ovarian cancer cells by upregulating the expression of E2F2 protein via binding to HuR protein. Zhang M, Xu Y, Zhang Y, Li B, Lou G. | 04/9/2022 |
Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells. | Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells. Feng H, Sun SZ, Cheng F, Zhang NQ., Free PMC Article | 02/5/2022 |
ChIP-sequencing analysis of E2F transcription factor 2 reveals its role in various biological processes of rheumatoid arthritis synovial fibroblasts. | ChIP-sequencing analysis of E2F transcription factor 2 reveals its role in various biological processes of rheumatoid arthritis synovial fibroblasts. Li L, Zhang Y, Wang L, Pan J. | 12/4/2021 |
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment. | E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment. González-Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A, Tamayo-Caro M, Varela-Rey M, Palomo-Irigoyen M, Gómez-Santos B, de Urturi DS, Núñez-García M, García-Rodríguez JL, Fernández-Ares L, Buqué X, Iglesias-Ara A, Bernales I, De Juan VG, Delgado TC, Goikoetxea-Usandizaga N, Lee R, Bhanot S, Delgado I, Perugorria MJ, Errazti G, Mosteiro L, Gaztambide S, Martinez de la Piscina I, Iruzubieta P, Crespo J, Banales JM, Martínez-Chantar ML, Castaño L, Zubiaga AM, Aspichueta P. | 11/6/2021 |
LBX2-AS1 promotes ovarian cancer progression by facilitating E2F2 gene expression via miR-455-5p and miR-491-5p sponging. | LBX2-AS1 promotes ovarian cancer progression by facilitating E2F2 gene expression via miR-455-5p and miR-491-5p sponging. Cao J, Wang H, Liu G, Tang R, Ding Y, Xu P, Wang H, Miao J, Gu X, Han S., Free PMC Article | 09/18/2021 |
E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer. | E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer. Li H, Zhao S, Shen L, Wang P, Liu S, Ma Y, Liang Z, Wang G, Lv J, Qiu W., Free PMC Article | 07/24/2021 |
Selected E2F2 Polymorphisms in Oral and Oropharyngeal Squamous Cell Carcinoma. | Selected E2F2 Polymorphisms in Oral and Oropharyngeal Squamous Cell Carcinoma. Gołąbek K, Biernacki K, Gaździcka J, Strzelczyk JK, Miśkiewicz-Orczyk K, Krakowczyk Ł, Zięba N, Kiczmer P, Ostrowska Z, Misiołek M., Free PMC Article | 05/29/2021 |
Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data. | Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data. Zeng Z, Cao Z, Tang Y., Free PMC Article | 05/15/2021 |
E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner. | E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner. Zhang L, Liu Z, Dong Y, Kong L. | 05/8/2021 |
Low E2F2 activity is associated with high genomic instability and PARPi resistance. | Low E2F2 activity is associated with high genomic instability and PARPi resistance. Rennhack JP, Andrechek ER., Free PMC Article | 04/13/2021 |
LncRNA NNT-AS1 regulates the progression of lung cancer through the NNT-AS1/miR-3666/E2F2 axis. | LncRNA NNT-AS1 regulates the progression of lung cancer through the NNT-AS1/miR-3666/E2F2 axis. Huang JW, Luo XY, Li ZH, Lang BP. | 01/2/2021 |
miR-638 represses the stem cell characteristics of breast cancer cells by targeting E2F2. | miR-638 represses the stem cell characteristics of breast cancer cells by targeting E2F2. Lin QY, Wang JQ, Wu LL, Zheng WE, Chen PR. | 09/26/2020 |
Downregulation of FLVCR1-AS1 inhibited proliferation, migration and invasion of glioma cells. FLVCR1-AS1 directly targeted miR-4731-5p/E2F2 axis. | Long noncoding RNA FLVCR1-AS1 aggravates biological behaviors of glioma cells via targeting miR-4731-5p/E2F2 axis. Yan Z, Zhang W, Xiong Y, Wang Y, Li Z. | 08/1/2020 |
DANCR knockdown inhibited growth and metastasis of PC cells. Furthermore, DANCR acted as sponge to regulate miR-214-5p, and miR-214-5p inhibitor reversed the effects of DANCR knockdown on PC cells. DANCR positively modulated E2F2 expression through miR-214-5p in PC cells. CONCLUSIONS Collectively, Findings demonstrated that lncRNA DANCR/miR-214-5p/E2F2 axis acts as an oncogene in PC development. | Long Non-Coding RNA Differentiation Antagonizing Nonprotein Coding RNA (DANCR) Promotes Proliferation and Invasion of Pancreatic Cancer by Sponging miR-214-5p to Regulate E2F2 Expression. Yao Z, Chen Q, Ni Z, Zhou L, Wang Y, Yang Y, Huang H., Free PMC Article | 01/18/2020 |
Cyclin F controls cell-cycle transcriptional outputs by directing the degradation of the E2F1, E2F2, and E2F3a. | Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M., Free PMC Article | 01/18/2020 |
MiR-490-5p inhibits the metastasis of hepatocellular carcinoma by down-regulating E2F2 and ECT2. | MiR-490-5p inhibits the metastasis of hepatocellular carcinoma by down-regulating E2F2 and ECT2. Fang ZQ, Li MC, Zhang YQ, Liu XG. | 10/12/2019 |
these findings indicate that E2F2 may play an important role in pathogenesis of rheumatoid arthritis. | A critical role of E2F transcription factor 2 in proinflammatory cytokines-dependent proliferation and invasiveness of fibroblast-like synoviocytes in rheumatoid Arthritis. Zhang R, Wang L, Pan JH, Han J., Free PMC Article | 08/24/2019 |