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    EDN1 endothelin 1 [ Homo sapiens (human) ]

    Gene ID: 1906, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Endothelin-1 (ET-1) contributes to senescence and phenotypic changes in brain pericytes in diabetes-mimicking conditions.

    Endothelin-1 (ET-1) contributes to senescence and phenotypic changes in brain pericytes in diabetes-mimicking conditions.
    Edgerton-Fulton M, Abdul Y, Jamil S, Ergul A.

    08/29/2024
    ET1 acts as a potential plasma biomarker and therapeutic target in deep venous thrombosis rat model.

    ET1 acts as a potential plasma biomarker and therapeutic target in deep venous thrombosis rat model.
    Wang Z, Wu Z, Hu Z, Zheng H, Chen Z., Free PMC Article

    08/15/2024
    The endothelin-1-driven tumor-stroma feed-forward loops in high-grade serous ovarian cancer.

    The endothelin-1-driven tumor-stroma feed-forward loops in high-grade serous ovarian cancer.
    Tocci P, Roman C, Sestito R, Caprara V, Sacconi A, Molineris I, Tonon G, Blandino G, Bagnato A., Free PMC Article

    07/13/2024
    Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein.

    Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein.
    Owen NE, Williams TL, Maguire JJ, Kuc RE, Davenport EE, Davenport AP.

    07/13/2024
    Diagnostic potential of endothelin-1 in peri-implant diseases: a cross-sectional study.

    Diagnostic potential of endothelin-1 in peri-implant diseases: a cross-sectional study.
    Saito Y, Nodai T, Munemasa T, Mukaibo T, Kondo Y, Masaki C, Hosokawa R., Free PMC Article

    06/27/2024
    Relationship between dynamic electrocardiogram and CRP, IL-6, ET-1 expression in myocardial ischemia patients with coronary heart disease.

    Relationship between dynamic electrocardiogram and CRP, IL-6, ET-1 expression in myocardial ischemia patients with coronary heart disease.
    You L.

    01/5/2024
    Association between endothelin-1 and systemic lupus erythematosus: insights from a case-control study.

    Association between endothelin-1 and systemic lupus erythematosus: insights from a case-control study.
    Li R, Yang C, Tang YY, Wang DC, Xu WD, Huang AF., Free PMC Article

    09/29/2023
    Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.

    Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.
    Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Müller GM, Walther T, Ashraf MI, Moll G, Morawietz H, Witowski J, Catar R.

    09/6/2023
    Association of blood pressure variability with Endothelin-1 by menopause status among Black women: findings from the Jackson Heart Study.

    Association of blood pressure variability with Endothelin-1 by menopause status among Black women: findings from the Jackson Heart Study.
    Rethy L, Polsinelli VB, Muntner P, Bello NA, Cohen JB., Free PMC Article

    08/9/2023
    Research progress on the role of ET-1 in diabetic kidney disease.

    Research progress on the role of ET-1 in diabetic kidney disease.
    Zhang S, Li X, Liu S, Zhang W, Li M, Qiao C.

    06/21/2023
    Plasma endothelin-1 may predict bevacizumab-induced proteinuria in patients with colorectal cancer.

    Plasma endothelin-1 may predict bevacizumab-induced proteinuria in patients with colorectal cancer.
    Nihei S, Ikeda T, Aoki T, Murasato F, Yaegashi M, Asahi K, Kudo K.

    05/8/2023
    Vascular parameters and endothelin-1 measurements in glaucoma patients with low- and high-tension optic disc hemorrhages.

    Vascular parameters and endothelin-1 measurements in glaucoma patients with low- and high-tension optic disc hemorrhages.
    Almeida INF, Taniguchi E, Tito CVA, Dias DT, Ushida M, Dorairaj S, Ritch R, Teixeira SH, Paranhos A Jr, Gracitelli CPB, Kayser C, Prata TS., Free PMC Article

    04/4/2023
    Hypoxic glioma cell-secreted exosomal circ101491 promotes the progression of glioma by regulating miR-125b-5p/EDN1.

    Hypoxic glioma cell-secreted exosomal circ101491 promotes the progression of glioma by regulating miR-125b-5p/EDN1.
    Zhang XH, Song YC, Qiu F, Wang ZC, Li N, Zhao FB.

    03/30/2023
    Endothelin-1 Induces Cell Proliferation and Myofibroblast Differentiation through the ETAR/Galphaq/ERK Signaling Pathway in Human Cardiac Fibroblasts.

    Endothelin-1 Induces Cell Proliferation and Myofibroblast Differentiation through the ET(A)R/G(αq)/ERK Signaling Pathway in Human Cardiac Fibroblasts.
    Duangrat R, Parichatikanond W, Likitnukul S, Mangmool S., Free PMC Article

    03/27/2023
    Potential role of eNOS and EDN-1 gene polymorphisms in the development and progression of retinopathy of prematurity.

    Potential role of eNOS and EDN-1 gene polymorphisms in the development and progression of retinopathy of prematurity.
    Choręziak-Michalak A, Gotz-Więckowska A, Chmielarz-Czarnocińska A, Seremak-Mrozikiewicz A, Szpecht D., Free PMC Article

    02/28/2023
    Epstein-Barr Virus Regulates Endothelin-1 Expression through the ERK/FOXO1 Pathway in EBV-Associated Gastric Cancer.

    Epstein-Barr Virus Regulates Endothelin-1 Expression through the ERK/FOXO1 Pathway in EBV-Associated Gastric Cancer.
    Liu W, Zhang Q, Zhang Y, Sun L, Xiao H, Luo B., Free PMC Article

    02/16/2023
    Endothelial Dysfunction Drives CRTd Outcome at 1-Year Follow-Up: A Novel Role as Biomarker for miR-130a-5p.

    Endothelial Dysfunction Drives CRTd Outcome at 1-Year Follow-Up: A Novel Role as Biomarker for miR-130a-5p.
    Sardu C, Santulli G, Savarese G, Trotta MC, Sacra C, Santamaria M, Volpicelli M, Ruocco A, Mauro C, Signoriello G, Marfella L, D'Amico M, Marfella R, Paolisso G., Free PMC Article

    01/28/2023
    [Serum levels of endothelin-1 and connective tissue growth factor are elevated in patients with atrial fibrillation and correlated with relapse following radiofrequency ablation].

    [Serum levels of endothelin-1 and connective tissue growth factor are elevated in patients with atrial fibrillation and correlated with relapse following radiofrequency ablation].
    Gao Q, Geng J, Ding Y, Yao Z, Meng J, Wang C, Zhang H, Kang P, Tang B., Free PMC Article

    01/11/2023
    High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ETA/ETB Receptor and mTOR Pathway.

    High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET(A)/ET(B) Receptor and mTOR Pathway.
    Pandey S, Madreiter-Sokolowski CT, Mangmool S, Parichatikanond W., Free PMC Article

    12/10/2022
    Increased endothelin-1 levels in coronary artery disease with diabetes mellitus in an Indonesian population.

    Increased endothelin-1 levels in coronary artery disease with diabetes mellitus in an Indonesian population.
    Inggriani MP, Musthafa A, Puspitawati I, Fachiroh J, Dewi FST, Hartopo AB.

    12/3/2022
    Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with beta-thalassemia major.

    Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major.
    Tantawy AAG, Tadros MAR, Adly AAM, Ismail EAR, Ibrahim FA, Salah Eldin NM, Hussein MM, Alfeky MA, Ibrahim SM, Hashem MA, Ebeid FSE.

    12/3/2022
    Gender differences in genotypic distribution of endothelin-1 gene and endothelin receptor A gene in pulmonary hypertension associated with rheumatic mitral valve disease.

    Gender differences in genotypic distribution of endothelin-1 gene and endothelin receptor A gene in pulmonary hypertension associated with rheumatic mitral valve disease.
    Mehra P, Mehta V, Yusuf J, Mukhopadhyay S, Dabla PK, Parashar L, Sukhija R, Aronow WS., Free PMC Article

    11/19/2022
    Microrna-486-5P Regulates Human Pulmonary Artery Smooth Muscle Cell Migration via Endothelin-1.

    Microrna-486-5P Regulates Human Pulmonary Artery Smooth Muscle Cell Migration via Endothelin-1.
    Yen TA, Huang HC, Wu ET, Chou HW, Chou HC, Chen CY, Huang SC, Chen YS, Lu F, Wu MH, Tsao PN, Wang CC., Free PMC Article

    10/8/2022
    The EDN1 Missense Variant rs5370G > T Regulates Adaptation and Maladaptation under Hypobaric Hypoxia.

    The EDN1 Missense Variant rs5370G > T Regulates Adaptation and Maladaptation under Hypobaric Hypoxia.
    Palmo T, Abbasi BA, Chanana N, Sharma K, Faruq M, Thinlas T, Abdin MZ, Pasha Q., Free PMC Article

    10/8/2022
    Exploring the pivotal role of endothelin in rheumatoid arthritis.

    Exploring the pivotal role of endothelin in rheumatoid arthritis.
    Sehgal A, Behl T, Singh S, Sharma N, Albratty M, Alhazmi HA, Meraya AM, Aleya L, Sharma A, Bungau S.

    10/8/2022
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