| EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway. | EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway.
Xu Z, Zhou Q, Liu C, Zhang H, Bai N, Xiang T, Luo D, Liu H., Free PMC Article | 11/4/2024 |
| Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein. | Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein.
Owen NE, Williams TL, Maguire JJ, Kuc RE, Davenport EE, Davenport AP. | 07/13/2024 |
| Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue. | Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Williams TL, Kuc RE, Paterson AL, Abraham GR, Pullinger AL, Maguire JJ, Sinha S, Greasley PJ, Ambery P, Davenport AP., Free PMC Article | 06/13/2024 |
| [Study of the clinical significance of ETAR mRNA expression in high-grade serous ovarian cancer and the inhibitory effect of ETAR derived fusion polypeptide on cancer progression]. | [Study of the clinical significance of ETAR mRNA expression in high-grade serous ovarian cancer and the inhibitory effect of ETAR derived fusion polypeptide on cancer progression].
Zhang YL, Xia XK, Zhang M. | 01/3/2024 |
| Role of interleukin-6 and endothelin-1 receptors in enhanced melanocyte dendricity of facial spots and suppression of their ligands by niacinamide and tranexamic acid. | Role of interleukin-6 and endothelin-1 receptors in enhanced melanocyte dendricity of facial spots and suppression of their ligands by niacinamide and tranexamic acid.
Hakozaki T, Wang J, Laughlin T, Jarrold B, Zhao W, Furue M. | 12/22/2023 |
| The interaction of beta-arrestin1 with talin1 driven by endothelin A receptor as a feature of alpha5beta1 integrin activation in high-grade serous ovarian cancer. | The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer.
Masi I, Ottavi F, Del Rio D, Caprara V, Vastarelli C, Giannitelli SM, Fianco G, Mozetic P, Buttarelli M, Ferrandina G, Scambia G, Gallo D, Rainer A, Bagnato A, Spadaro F, Rosanò L., Free PMC Article | 02/4/2023 |
| High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ETA/ETB Receptor and mTOR Pathway. | High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET(A)/ET(B) Receptor and mTOR Pathway.
Pandey S, Madreiter-Sokolowski CT, Mangmool S, Parichatikanond W., Free PMC Article | 12/10/2022 |
| Endothelin A receptors contribute to senescence of brain microvascular endothelial cells. | Endothelin A receptors contribute to senescence of brain microvascular endothelial cells.
Abdul Y, Karakaya E, Chandran R, Jamil S, Ergul A., Free PMC Article | 12/3/2022 |
| Gender differences in genotypic distribution of endothelin-1 gene and endothelin receptor A gene in pulmonary hypertension associated with rheumatic mitral valve disease. | Gender differences in genotypic distribution of endothelin-1 gene and endothelin receptor A gene in pulmonary hypertension associated with rheumatic mitral valve disease.
Mehra P, Mehta V, Yusuf J, Mukhopadhyay S, Dabla PK, Parashar L, Sukhija R, Aronow WS., Free PMC Article | 11/19/2022 |
| Association of polymorphisms in endothelin-1 and endothelin receptor a genes with vasovagal syncope. | Association of polymorphisms in endothelin-1 and endothelin receptor a genes with vasovagal syncope.
Lazurova Z, Habalova V, Mitro P., Free PMC Article | 04/23/2022 |
| Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via beta2-arrestin link to mTOR pathway. | Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway.
Catar RA, Wischnewski O, Chen L, Heidecke H, Rutz C, Schülein R, Dragun D, Philippe A, Kusch A. | 03/19/2022 |
| Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line. | Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line.
Torres MJ, López-Moncada F, Herrera D, Indo S, Lefian A, Llanos P, Tapia J, Castellón EA, Contreras HR., Free PMC Article | 12/4/2021 |
| Homology modeling, molecular dynamics and virtual screening of endothelin-A receptor for the treatment of pulmonary arterial hypertension. | Homology modeling, molecular dynamics and virtual screening of endothelin-A receptor for the treatment of pulmonary arterial hypertension.
Gu X, Wang Y, Wang H, Wu H, Li W, Wang J, Li N. | 08/21/2021 |
| Diabetes-related sex differences in the brain endothelin system following ischemia in vivo and in human brain endothelial cells in vitro. | Diabetes-related sex differences in the brain endothelin system following ischemia in vivo and in human brain endothelial cells in vitro.
Abdul Y, Li W, Vargas JD, Grant E, He L, Jamil S, Ergul A., Free PMC Article | 07/10/2021 |
| Endothelin receptor heteromerization inhibits beta-arrestin function in HEK293 cells. | Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.
Zrein A, Bagher AM, Young AP, Denovan-Wright EM, Kelly MEM. | 06/5/2021 |
| The role of endothelin A receptors in peripheral vascular control at rest and during exercise in patients with hypertension. | The role of endothelin A receptors in peripheral vascular control at rest and during exercise in patients with hypertension.
Craig JC, Broxterman RM, La Salle DT, Cerbie J, Ratchford SM, Gifford JR, Bunsawat K, Nelson AD, Bledsoe AD, Morgan DE, Wray DW, Richardson RS, Trinity JD., Free PMC Article | 02/13/2021 |
| Loss-of-function of Endothelin receptor type A results in Oro-Oto-Cardiac syndrome. | Loss-of-function of Endothelin receptor type A results in Oro-Oto-Cardiac syndrome.
Pritchard AB, Kanai SM, Krock B, Schindewolf E, Oliver-Krasinski J, Khalek N, Okashah N, Lambert NA, Tavares ALP, Zackai E, Clouthier DE., Free PMC Article | 01/16/2021 |
| Effects of genotype on TENS effectiveness in controlling knee pain in persons with mild to moderate osteoarthritis. | Effects of genotype on TENS effectiveness in controlling knee pain in persons with mild to moderate osteoarthritis.
Govil M, Mukhopadhyay N, Holwerda T, Sluka K, Rakel B, Schutte DL. | 11/28/2020 |
| Endothelins and their receptors in embryo implantation. | Endothelins and their receptors in embryo implantation.
Mihanfar A, Sadigh AR, Fattahi A, Latifi Z, Hasanzadeh-Moghadam M, Samadi M, Farzadi L, Hamdi K, Ghasemzadeh A, Nejabati HR, Nouri M. | 08/22/2020 |
| The findings suggest that ETAR expression, as detected by Immunohistochemical staining, could be useful as a molecular marker to predict prognosis for gastric cancer patients. | Endothelin-A receptor in gastric cancer and enhanced antitumor activity of trastuzumab in combination with the endothelin-A receptor antagonist ZD4054.
Shen W, Xi H, Li C, Bian S, Cheng H, Cui J, Wang N, Wei B, Huang X, Chen L. | 04/11/2020 |
| The ENDRA rs5333 gene polymorphism may be associated with genetic predisposition to steroid resistance in idiopathic nephrotic syndrome Egyptian children | Association of endothelin receptor type A rs5333 gene polymorphism with steroid response in Egyptian children with idiopathic nephrotic syndrome.
Ezzat GM, Ali AB, Mohamed NA, Hetta HF. | 03/21/2020 |
| In this systematic review, the genetic variant of EDNRA, rs6841581, was significantly associated with increased risk of intracranial aneurysm. | Association of Endothelin Receptor Type A with Intracranial Aneurysm in 20,609 East Asians: An Updated Meta-Analysis.
Hong EP, Kim BJ, Jeon JP, Yang JS, Choi HJ, Kang SH, Cho YJ. | 01/25/2020 |
| These findings support the important role of EDNRA and EDNRB polymorphisms in intracerebral hemorrhage, and suggest that they do not interact with blood pressure levels on altering intracerebral hemorrhage risk. | Associations of EDNRA and EDNRB Polymorphisms with Intracerebral Hemorrhage.
Zeng Y, Chen R, Ma M, Liu B, Xia J, Xu H, Liu Y, Du X, Hu Z, Yang Q, Zhang L. | 01/25/2020 |
| Subjects with either TC or CC genotypes at rs5333 exhibited significantly greater increases in brachial-ankle pulse wave velocity with age | Effects of endothelin-related gene polymorphisms and aerobic exercise habit on age-related arterial stiffening: a 10-yr longitudinal study.
Sugawara J, Tomoto T, Noda N, Matsukura S, Tsukagoshi K, Hayashi K, Hieda M, Maeda S. | 10/26/2019 |
| Common endothelin SNPs were found to be associated with aneurysmal subarachnoid hemorrhage (aSAH) and its sequelae. The T allele of the END1 T/G SNP (rs1800541) was associated with aSAH. The G allele of the EDNRA G/C SNP (rs5335) was associated with clinical vasospasm. | Associations between endothelin polymorphisms and aneurysmal subarachnoid hemorrhage, clinical vasospasm, delayed cerebral ischemia, and functional outcome.
Griessenauer CJ, Starke RM, Foreman PM, Hendrix P, Harrigan MR, Fisher WS, Vyas NA, Lipsky RH, Lin M, Walters BC, Pittet JF, Mathru M. | 09/14/2019 |