| Interference of EFNA4 suppresses cell proliferation, invasion and angiogenesis in hepatocellular carcinoma by downregulating PYGO2. | Interference of EFNA4 suppresses cell proliferation, invasion and angiogenesis in hepatocellular carcinoma by downregulating PYGO2.
Yuan W, Zhao H, Zhou A, Wang S., Free PMC Article | 11/26/2022 |
| Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. | Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells.
Chen YL, Yen YC, Jang CW, Wang SH, Huang HT, Chen CH, Hsiao JR, Chang JY, Chen YW., Free PMC Article | 08/14/2021 |
| Study present for the first time in vitro and in vivo evidence suggesting that the major role of two ephrin A4 isoforms in chronic lymphocytic leukemia could be related with a non-previously described mechanism of survival linked to extravasation strongly dependent on integrin signaling. | EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation.
Flores MA, Fortea P, Trinidad EM, García D, Soler G, Ortuño FJ, Zapata AG, Alonso-Colmenar LM., Free PMC Article | 01/13/2018 |
| The present study provides evidence that microglia upregulates endothelial ephrin-A3 and ephrin-A4 to facilitate in vitro angiogenesis of brain endothelial cells, which is mediated by microglia-released TNF-alpha. | Ephrin-A3 and ephrin-A4 contribute to microglia-induced angiogenesis in brain endothelial cells.
Li Y, Liu DX, Li MY, Qin XX, Fang WG, Zhao WD, Chen YH. | 05/30/2015 |
| The interaction between ephrin-As, Eph receptors and integrin alpha3 is plausibly important for the crosstalk between Eph and integrin signalling pathways at the membrane protrusions and in the migration of brain cancer cells. | Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.
Makarov A, Ylivinkka I, Nyman TA, Hyytiäinen M, Keski-Oja J. | 05/31/2014 |
| Observational study of gene-disease association. (HuGE Navigator) | Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis.
Wilkie AO, Byren JC, Hurst JA, Jayamohan J, Johnson D, Knight SJ, Lester T, Richards PG, Twigg SR, Wall SA., Free PMC Article | 12/5/2010 |
| The cytoplasmic pattern of ephrin A4 could identify a subgroup of primary osteosarcoma patients with a high liability for progression, poor prognosis, and inferior response to chemotherapy. | Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome.
Abdou AG, Abd el-Wahed MM, Asaad NY, Samaka RM, Abdallaha R. | 03/29/2010 |
| EFNA4-EphA2 interactions are involved in Chronic lymphocytic leukemia cell trafficking between blood and the tissues | An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression.
Trinidad EM, Ballesteros M, Zuloaga J, Zapata A, Alonso-Colmenar LM. | 01/21/2010 |
| CLL B-cells showed a more heterogeneous Eph/EFN profile, specially EFNA4, EphB6 and EphA10. EphB6 and EFNA4 were further related with the clinical course of CLL. | Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells.
Alonso-C LM, Trinidad EM, de Garcillan B, Ballesteros M, Castellanos M, Cotillo I, Muñoz JJ, Zapata AG. | 01/21/2010 |
| This provides genetic evidence that Twist1, Msx2 and Efna4 function together in boundary formation and the pathogenesis of coronal synostosis. | Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis.
Merrill AE, Bochukova EG, Brugger SM, Ishii M, Pilz DT, Wall SA, Lyons KM, Wilkie AO, Maxson RE Jr. | 01/21/2010 |
| Characterization of the promoter | Characterization of the human ephrin-A4 promoter.
Munthe E, Aasheim HC., Free PMC Article | 01/21/2010 |