Alpha-2-Macroglobulin Is a Novel Anticancer Agent. | Alpha-2-Macroglobulin Is a Novel Anticancer Agent. Facchiano F, D'Arcangelo D, Facchiano A., Free PMC Article | 07/23/2024 |
CCCTC-binding factor suppresses alpha-2-macroglobulin transcription to improve vascular endothelial cell functions in lower extremity arteriosclerosis obliterans. | CCCTC-binding factor suppresses alpha-2-macroglobulin transcription to improve vascular endothelial cell functions in lower extremity arteriosclerosis obliterans. He T, You M, Zhu H, Chen P, Fang S. | 06/7/2024 |
Tandem Mass Tag-Labeled Quantitative Proteome Analyses Identify C1R and A2M as Novel Serum Biomarkers in Pregnant Women with Obstructive Sleep Apnea. | Tandem Mass Tag-Labeled Quantitative Proteome Analyses Identify C1R and A2M as Novel Serum Biomarkers in Pregnant Women with Obstructive Sleep Apnea. Zhang Q, Yue Y, Wang X, Cui H, Liu Y, Gao M, Liu T, Xiao L. | 04/11/2024 |
[Pathogenetic role of multifunctional protein alpha-2-macroglobulin and its activity in tears and serum in age-related macular degeneration and proliferative diabetic retinopathy]. | [Pathogenetic role of multifunctional protein alpha-2-macroglobulin and its activity in tears and serum in age-related macular degeneration and proliferative diabetic retinopathy]. Neroev VV, Chesnokova NB, Neroeva NV, Beznos OV, Pavlenko TA, Okhotsimskaya TD, Utkina OA. | 01/30/2024 |
Alpha-2 macroglobulin activity in SARS-CoV-2 induced infection and in the post-COVID-19 period. | Alpha-2 macroglobulin activity in SARS-CoV-2 induced infection and in the post-COVID-19 period. Akbasheva OE, Mitrofanova DK, Spirina LV, Samoilova YG, Matveeva MV, Podchinenova DV, Oleynik OA. | 09/19/2023 |
Alpha-2-macroglobulin prevents platelet aggregation induced by brain-derived neurotrophic factor. | Alpha-2-macroglobulin prevents platelet aggregation induced by brain-derived neurotrophic factor. Jourdi G, Boukhatem I, Barcelona PF, Fleury S, Welman M, Saragovi HU, Pasquali S, Lordkipanidzé M. | 09/7/2023 |
Alpha-2-Macroglobulin (A2M) and Dopamine Receptor D2 (DRD2) expression analysis and Influence of Separation from Parents in Childhood on the Suicide and Self-injury Behavior and Psychological Adjustment in Adolescence. | Alpha-2-Macroglobulin (A2M) and Dopamine Receptor D2 (DRD2) expression analysis and Influence of Separation from Parents in Childhood on the Suicide and Self-injury Behavior and Psychological Adjustment in Adolescence. Xu Q, Xu H, Li S. | 05/25/2023 |
Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis. | Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis. Wang J, Zhang P, Liu M, Huang Z, Yang X, Ding Y, Liu J, Cheng X, Xu S, He M, Zhang F, Wang G, Li R, Yang X., Free PMC Article | 03/17/2023 |
LincRNA00612 inhibits apoptosis and inflammation in LPS-induced BEAS-2B cells via enhancing interaction between p-STAT3 and A2M promoter. | LincRNA00612 inhibits apoptosis and inflammation in LPS-induced BEAS-2B cells via enhancing interaction between p-STAT3 and A2M promoter. Xiao X, Cai W, Ding Z, Mao Z, Shi Y, Zhang Q., Free PMC Article | 03/9/2023 |
A2M inhibits inflammatory mediators of chondrocytes by blocking IL-1beta/NF-kappaB pathway. | A2M inhibits inflammatory mediators of chondrocytes by blocking IL-1β/NF-κB pathway. Sun C, Cao C, Zhao T, Guo H, Fleming BC, Owens B, Beveridge J, McAllister S, Wei L. | 12/17/2022 |
Association of salivary alpha-2-macroglobulin with glycemia and glycated hemoglobin in type 2 diabetes mellitus: a systematic review and meta-analysis study. | Association of salivary alpha-2-macroglobulin with glycemia and glycated hemoglobin in type 2 diabetes mellitus: a systematic review and meta-analysis study. Caixeta DC, Pennisi PRC, Moura DV, Nunes MAC, Espindola FS, Blumenberg C, Paranhos LR, Sabino-Silva R., Free PMC Article | 11/19/2022 |
Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort. | Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort. Dong L, Mao C, Liu C, Li J, Huang X, Wang J, Lei D, Chu S, Sha L, Xu Q, Peng B, Cui L, Gao J., Free PMC Article | 03/5/2022 |
A mass spectrometric approach to study the interaction of amyloid beta peptides with human alpha-2-macroglobulin. | A mass spectrometric approach to study the interaction of amyloid β peptides with human α-2-macroglobulin. Protasov AV, Mirgorodskaya OA, Kozmin YP, Gobom J. | 02/5/2022 |
Production of Recombinant Polypeptides Binding alpha2-Macroglobulin and Analysis of Their Ability to Bind Human Serum alpha2-Macroglobulin. | Production of Recombinant Polypeptides Binding α2-Macroglobulin and Analysis of Their Ability to Bind Human Serum α2-Macroglobulin. Bormotova EA, Gupalova TV. | 07/10/2021 |
Interaction of Human Alpha-2-Macroglobulin with Pesticide Aldicarb Using Spectroscopy and Molecular Docking. | Interaction of Human Alpha-2-Macroglobulin with Pesticide Aldicarb Using Spectroscopy and Molecular Docking. Dixit S, Zia MK, Siddiqui T, Ahsan H, Khan FH. | 07/3/2021 |
The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia. | The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia. Naseraldeen N, Michelis R, Barhoum M, Chezar J, Tadmor T, Aviv A, Shvidel L, Litmanovich A, Shehadeh M, Stemer G, Shaoul E, Braester A., Free PMC Article | 06/26/2021 |
Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. | Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. N'Guessan K, Grzywa R, Seren S, Gabant G, Juliano MA, Moniatte M, van Dorsselaer A, Bieth JG, Kellenberger C, Gauthier F, Wysocka M, Lesner A, Sienczyk M, Cadene M, Korkmaz B. | 05/22/2021 |
The effect of adrenocorticotropic hormone on alpha-2-macroglobulin in osteoblasts derived from human mesenchymal stem cells. | The effect of adrenocorticotropic hormone on alpha-2-macroglobulin in osteoblasts derived from human mesenchymal stem cells. Sadeghi F, Vahednia E, Naderi Meshkin H, Kerachian MA., Free PMC Article | 05/1/2021 |
GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of alpha2M. | GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of α2M. Liu C, Li Z, Xu L, Shi Y, Zhang X, Shi S, Hou K, Fan Y, Li C, Wang X, Zhou L, Liu Y, Qu X, Che X., Free PMC Article | 03/13/2021 |
Activated alpha2-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion. | Activated α(2)-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion. Bastida-Ruiz D, Wuillemin C, Pederencino A, Yaron M, Martinez de Tejada B, Pizzo SV, Cohen M., Free PMC Article | 12/12/2020 |
Molecular form and concentration of serum alpha2-macroglobulin in diabetes. | Molecular form and concentration of serum α(2)-macroglobulin in diabetes. Yoshino S, Fujimoto K, Takada T, Kawamura S, Ogawa J, Kamata Y, Kodera Y, Shichiri M., Free PMC Article | 10/31/2020 |
The results suggest that A2M positively regulates Microvesicle shedding through the activation of LRP1 on myofibroblasts. | α-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. Laberge A, Ayoub A, Arif S, Larochelle S, Garnier A, Moulin VJ. | 05/9/2020 |
Significantly lower levels of alpha-2-macroglobulin were found in the serum of patients with steroid-induced necrosis of the femoral head (SINFH) than in controls (P < 0.05). Immunohistochemical staining and western blotting demonstrated that the expression of alpha-2-macroglobulin was significantly decreased in the necrotic area of SINFH patients (P < 0.05). | Relationship of α2-Macroglobulin with Steroid-Induced Femoral Head Necrosis: A Chinese Population-Based Association Study in Southeast China. Fang SH, Li YF, Jiang JR, Chen P., Free PMC Article | 01/11/2020 |
High A2M expression is associated with Pancreatic cancer. | Pancreatic cancer biomarker detection by two support vector strategies for recursive feature elimination. Wang Y, Liu K, Ma Q, Tan Y, Du W, Lv Y, Tian Y, Wang H., Free PMC Article | 01/11/2020 |
Impaired fibrinolysis and lower levels of alpha2-macroglobulin might predispose to a higher rate of asthma exacerbations, suggesting new links between disturbed hemostasis and asthma. | Impaired fibrinolysis and lower levels of plasma α(2)-macroglobulin are associated with an increased risk of severe asthma exacerbations. Bazan-Socha S, Mastalerz L, Cybulska A, Zareba L, Kremers R, Zabczyk M, Pulka G, Iwaniec T, Bazan JG, Hemker C, Undas A., Free PMC Article | 06/8/2019 |