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    Cx3cl1 C-X3-C motif chemokine ligand 1 [ Mus musculus (house mouse) ]

    Gene ID: 20312, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma.

    Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma.
    Eain HS, Kawai H, Nakayama M, Oo MW, Ohara T, Fukuhara Y, Takabatake K, Shan Q, Soe Y, Ono K, Nakano K, Mizukawa N, Iida S, Nagatsuka H., Free PMC Article

    10/8/2024
    CX3CL1 release during immunogenic apoptosis is associated with enhanced anti-tumour immunity.

    CX3CL1 release during immunogenic apoptosis is associated with enhanced anti-tumour immunity.
    Naessens F, Demuynck R, Vershinina O, Efimova I, Saviuk M, De Smet G, Mishchenko TA, Vedunova MV, Krysko O, Catanzaro E, Krysko DV., Free PMC Article

    07/22/2024
    Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling.

    Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling.
    Frias-Anaya E, Gallego-Gutierrez H, Gongol B, Weinsheimer S, Lai CC, Orecchioni M, Sriram A, Bui CM, Nelsen B, Hale P, Pham A, Shenkar R, DeBiasse D, Lightle R, Girard R, Li Y, Srinath A, Daneman R, Nudleman E, Sun H, Guma M, Dubrac A, Mesarwi OA, Ley K, Kim H, Awad IA, Ginsberg MH, Lopez-Ramirez MA.,

    05/29/2024
    Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina.

    Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina.
    Rodriguez D, Church KA, Pietramale AN, Cardona SM, Vanegas D, Rorex C, Leary MC, Muzzio IA, Nash KR, Cardona AE., Free PMC Article

    03/7/2024
    Inhibition of CX3CL1 by treadmill training prevents osteoclast-induced fibrocartilage complex resorption during TBI healing.

    Inhibition of CX3CL1 by treadmill training prevents osteoclast-induced fibrocartilage complex resorption during TBI healing.
    Liu X, Zhou M, Tan J, Ma L, Tang H, He G, Tao X, Guo L, Kang X, Tang K, Bian X., Free PMC Article

    03/1/2024
    Hypothalamic FTO promotes high-fat diet-induced leptin resistance in mice through increasing CX3CL1 expression.

    Hypothalamic FTO promotes high-fat diet-induced leptin resistance in mice through increasing CX3CL1 expression.
    Liu S, Song S, Wang S, Cai T, Qin L, Wang X, Zhu G, Wang H, Yang W, Fang C, Wei Y, Zhou F, Yu Y, Lin S, Peng S, Li L.

    12/16/2023
    Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions.

    Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions.
    Mikosz A, Ni K, Gally F, Pratte KA, Winfree S, Lin Q, Echelman I, Wetmore B, Cao D, Justice MJ, Sandhaus RA, Maier L, Strange C, Bowler RP, Petrache I, Serban KA.,

    11/18/2023
    Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury.

    Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury.
    Gong Q, Lai T, Liang L, Jiang Y, Liu F., Free PMC Article

    10/28/2023
    CX3CL1 represses autophagy via CX3CR1/ CaMKIIdelta/HDAC4/Rubicon axis and exacerbates chronic intermittent hypoxia induced Kupffer cell apoptosis.

    CX3CL1 represses autophagy via CX3CR1/ CaMKIIδ/HDAC4/Rubicon axis and exacerbates chronic intermittent hypoxia induced Kupffer cell apoptosis.
    Li Y, Chen Y, Xiao X, Deng S, Kuang J, Wang Y.

    10/10/2023
    Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling.

    Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling.
    Ribeiro R, Silva EG, Moreira FC, Gomes GF, Cussat GR, Silva BSR, da Silva MCM, de Barros Fernandes H, de Sena Oliveira C, de Oliveira Guarnieri L, Lopes V, Ferreira CN, de Faria AMC, Maioli TU, Ribeiro FM, de Miranda AS, Moraes GSP, de Oliveira ACP, Vieira LB., Free PMC Article

    10/10/2023
    CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation through NF-kappaB signaling pathway in ankylosing spondylitis in vitro.

    CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation through NF-κB signaling pathway in ankylosing spondylitis in vitro.
    Feng X, Zhu S, Qiao J, Ji Z, Zhou B, Xu W., Free PMC Article

    08/30/2023
    Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer.

    Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer.
    Bocanegra A, Fernández-Hinojal G, Ajona D, Blanco E, Zuazo M, Garnica M, Chocarro L, Alfaro-Arnedo E, Piñeiro-Hermida S, Morente P, Fernández L, Remirez A, Echaide M, Martinez-Aguillo M, Morilla I, Tavira B, Roncero A, Gotera C, Ventura A, Recalde N, Pichel JG, Lasarte JJ, Montuenga L, Vera R, Pio R, Escors D, Kochan G., Free PMC Article

    08/4/2023
    Blockage of CX3CL1 Attenuates Platelet and Leukocyte Recruitment in Murine Hepatic I/R.

    Blockage of CX3CL1 Attenuates Platelet and Leukocyte Recruitment in Murine Hepatic I/R.
    Funken D, Brüggemann A, Mende K, Lerchenberger M, Rentsch M, Khandoga A., Free PMC Article

    06/26/2023
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling.

    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling.
    Gayen M, Benoit MR, Fan Q, Hudobenko J, Yan R., Free PMC Article

    12/3/2022
    CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status.

    CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status.
    Ni Y, Zhuge F, Ni L, Nagata N, Yamashita T, Mukaida N, Kaneko S, Ota T, Nagashimada M.

    10/8/2022
    CX3CL1 inhibits NLRP3 inflammasome-induced microglial pyroptosis and improves neuronal function in mice with experimentally-induced ischemic stroke.

    CX3CL1 inhibits NLRP3 inflammasome-induced microglial pyroptosis and improves neuronal function in mice with experimentally-induced ischemic stroke.
    Ge Y, Wang L, Wang C, Chen J, Dai M, Yao S, Lin Y.

    05/28/2022
    Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis.

    Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis.
    Sun Y, Zhang XX, Huang S, Pan H, Gai YZ, Zhou YQ, Zhu L, Nie HZ, Li DX., Free PMC Article

    05/7/2022
    Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells.

    Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells.
    Watson AES, de Almeida MMA, Dittmann NL, Li Y, Torabi P, Footz T, Vetere G, Galleguillos D, Sipione S, Cardona AE, Voronova A., Free PMC Article

    03/19/2022
    Compromised fractalkine signaling delays microglial occupancy of emerging modules in the multisensory midbrain.

    Compromised fractalkine signaling delays microglial occupancy of emerging modules in the multisensory midbrain.
    Brett CA, Carroll JB, Gabriele ML., Free PMC Article

    03/19/2022
    Role of Fractalkine-CX3CR1 Axis in Acute Rejection of Mouse Heart Allografts Subjected to Ischemia Reperfusion Injury.

    Role of Fractalkine-CX3CR1 Axis in Acute Rejection of Mouse Heart Allografts Subjected to Ischemia Reperfusion Injury.
    Kanzawa T, Tokita D, Saiga K, Yamakawa T, Ishigooka H, Fukuda H, Katsumata H, Miyairi S, Ishii R, Hirai T, Imai T, Okumi M, Tanabe K., Free PMC Article

    03/5/2022
    Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy.

    Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy.
    Mills SA, Jobling AI, Dixon MA, Bui BV, Vessey KA, Phipps JA, Greferath U, Venables G, Wong VHY, Wong CHY, He Z, Hui F, Young JC, Tonc J, Ivanova E, Sagdullaev BT, Fletcher EL., Free PMC Article

    01/15/2022
    Orthopedic surgery-induced cognitive dysfunction is mediated by CX3CL1/R1 signaling.

    Orthopedic surgery-induced cognitive dysfunction is mediated by CX3CL1/R1 signaling.
    Cho I, Kim JM, Kim EJ, Kim SY, Kam EH, Cheong E, Suh M, Koo BN., Free PMC Article

    11/22/2021
    CX3CL1-CX3CR1 Signaling Deficiency Exacerbates Obesity-induced Inflammation and Insulin Resistance in Male Mice.

    CX3CL1-CX3CR1 Signaling Deficiency Exacerbates Obesity-induced Inflammation and Insulin Resistance in Male Mice.
    Nagashimada M, Sawamoto K, Ni Y, Kitade H, Nagata N, Xu L, Kobori M, Mukaida N, Yamashita T, Kaneko S, Ota T.

    10/9/2021
    Association of CX3CL1 and CX3CR1 Expression with Liver Fibrosis in a Mouse Model of Schistosomiasis.

    Association of CX3CL1 and CX3CR1 Expression with Liver Fibrosis in a Mouse Model of Schistosomiasis.
    Zhang P, Wang BJ, Wang JZ, Xie XM, Tong QX.

    09/25/2021
    PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1.

    PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1.
    Zhang Q, He L, Chen M, Yang H, Cao X, Liu X, Hao Q, Chen Z, Liu T, Wei XE, Rong L.

    08/28/2021
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