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    Shh sonic hedgehog [ Mus musculus (house mouse) ]

    Gene ID: 20423, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth.

    Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth.
    Guyodo H, Rizzo A, Diab F, Noury F, Mironov S, de Tayrac M, David V, Odent S, Dubourg C, Dupé V., Free PMC Article

    04/4/2024
    Characterization of Sonic Hedgehog transcripts in the adult mouse brain: co-expression with neuronal and oligodendroglial markers.

    Characterization of Sonic Hedgehog transcripts in the adult mouse brain: co-expression with neuronal and oligodendroglial markers.
    Russo M, Pellegrino G, Faure H, Tirou L, Sharif A, Ruat M., Free PMC Article

    03/29/2024
    TRIP6 promotes neural stem cell maintenance through YAP-mediated Sonic Hedgehog activation.

    TRIP6 promotes neural stem cell maintenance through YAP-mediated Sonic Hedgehog activation.
    Li MY, Yang XL, Chung CC, Lai YJ, Tsai JC, Kuo YL, Yu JY, Wang TW.

    02/28/2024
    SALL4 is a CRL3[REN/KCTD11] substrate that drives Sonic Hedgehog-dependent medulloblastoma.

    SALL4 is a CRL3(REN/KCTD11) substrate that drives Sonic Hedgehog-dependent medulloblastoma.
    Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L., Free PMC Article

    02/12/2024
    Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression.

    Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression.
    Hasselluhn MC, Decker-Farrell AR, Vlahos L, Thomas DH, Curiel-Garcia A, Maurer HC, Wasko UN, Tomassoni L, Sastra SA, Palermo CF, Dalton TC, Ma A, Li F, Tolosa EJ, Hibshoosh H, Fernandez-Zapico ME, Muir A, Califano A, Olive KP., Free PMC Article

    02/12/2024
    Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis.

    Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis.
    Pei F, Ma L, Guo T, Zhang M, Jing J, Wen Q, Feng J, Lei J, He J, Janečková E, Ho TV, Chen JF, Chai Y.,

    01/15/2024
    Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration.

    Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration.
    Orzechowska-Licari EJ, Bialkowska AB, Yang VW., Free PMC Article

    09/26/2023
    [Effect study of Sonic hedgehog overexpressed hair follicle stem cells in hair follicle regeneration].

    [Effect study of Sonic hedgehog overexpressed hair follicle stem cells in hair follicle regeneration].
    Yang Y, Wang G, Yang Q, Diao B., Free PMC Article

    07/20/2023
    The SHH-GLI1 pathway is required in skin expansion and angiogenesis.

    The SHH-GLI1 pathway is required in skin expansion and angiogenesis.
    Zhang X, Chen Y, Ding P, Lin Z, Sun Z, Jin M, Li C, Zhao Z, Bi H.

    07/12/2023
    IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice.

    IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice.
    Li B, Yan YP, He YY, Liang C, Li MY, Wang Y, Yang ZM.

    03/8/2023
    Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.

    Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.
    Zhou P, Xu Y, Yang L, Meng P, Guo J, Liu Z, Jin B, Xie K, Zhu H, Du L, Jin X.

    12/10/2022
    ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development.

    ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development.
    Zhang W, Yu J, Fu G, Li J, Huang H, Liu J, Yu D, Qiu M, Li F.

    10/29/2022
    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.

    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
    Wang S, Tanaka Y, Xu Y, Takeda S, Hirokawa N.

    10/15/2022
    The Primary Ciliary Deficits in Cerebellar Bergmann Glia of the Mouse Model of Fragile X Syndrome.

    The Primary Ciliary Deficits in Cerebellar Bergmann Glia of the Mouse Model of Fragile X Syndrome.
    Lee B, Beuhler L, Lee HY., Free PMC Article

    09/3/2022
    Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.

    Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
    Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ, Wurst W., Free PMC Article

    08/27/2022
    Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud.

    Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud.
    Koyano-Nakagawa N, Gong W, Das S, Theisen JWM, Swanholm TB, Van Ly D, Dsouza N, Singh BN, Kawakami H, Young S, Chen KQ, Kawakami Y, Garry DJ., Free PMC Article

    07/30/2022
    STAT3 is required for Smo-dependent signaling and mediates Smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma.

    STAT3 is required for Smo-dependent signaling and mediates Smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma.
    Yuan L, Zhang H, Liu J, Malhotra A, Dey A, Yu B, Jella KK, McSwain LF, Schniederjan MJ, MacDonald TJ., Free PMC Article

    07/9/2022
    SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation.

    SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation.
    Adolphe C, Millar A, Kojic M, Barkauskas DS, Sundström A, Swartling FJ, Hediyeh-Zadeh S, Tan CW, Davis MJ, Genovesi LA, Wainwright BJ.

    03/26/2022
    An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.

    An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
    Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Günther A, Stainier DYR, Samakovlis C., Free PMC Article

    03/12/2022
    A subpopulation of astrocyte progenitors defined by Sonic hedgehog signaling.

    A subpopulation of astrocyte progenitors defined by Sonic hedgehog signaling.
    Gingrich EC, Case K, Garcia ADR., Free PMC Article

    03/12/2022
    Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.

    Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.
    Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB., Free PMC Article

    03/5/2022
    HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.

    HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
    Sharma D, Mirando AJ, Leinroth A, Long JT, Karner CM, Hilton MJ., Free PMC Article

    02/19/2022
    FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development.

    FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development.
    Meuser M, Deuper L, Rudat C, Aydoğdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A.

    02/12/2022
    SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.

    SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.
    Gamart J, Barozzi I, Laurent F, Reinhardt R, Martins LR, Oberholzer T, Visel A, Zeller R, Zuniga A., Free PMC Article

    02/5/2022
    Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.

    Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.
    Zhang C, Li Y, Cao J, Yu B, Zhang K, Li K, Xu X, Guo Z, Liang Y, Yang X, Yang Z, Sun Y, Kaartinen V, Ding K, Wang J., Free PMC Article

    02/5/2022
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