| CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV. | CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.
Immler R, Nussbaumer K, Doerner A, El Bounkari O, Huber S, Abisch J, Napoli M, Schmidt S, Margraf A, Pruenster M, Rohwedder I, Lange-Sperandio B, Mall MA, de Jong R, Ohnmacht C, Bernhagen J, Voehringer D, Marth JD, Frommhold D, Sperandio M., Free PMC Article | 05/8/2024 |
| Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression. | Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression.
Chen X, Wang L, Wu Y, Zhang H, Dong W, Yu X, Huang C, Li Y, Wang S, Zhang J. | 03/5/2022 |
| The results of this study indicated that ST3Gal IV is a key molecule in the mechanisms underlying anxiety - a side effect of TLE - and may therefore also be an effective target for treating epilepsy, acting through the same circuits. | Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy.
Srimontri P, Endo S, Sakamoto T, Nakayama Y, Kurosaka A, Itohara S, Hirabayashi Y, Kato K. | 01/17/2015 |
| St3Gal4-deficient myeloid cells had less binding of Ccl5 and impaired Ccl5-triggered integrin activation. St3Gal4 deficiency reduced the size, stage, and inflammatory cell content of atherosclerotic lesions in Apoe(-/-) mice on high-fat diet. | Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication.
Döring Y, Noels H, Mandl M, Kramp B, Neideck C, Lievens D, Drechsler M, Megens RT, Tilstam PV, Langer M, Hartwig H, Theelen W, Marth JD, Sperandio M, Soehnlein O, Weber C., Free PMC Article | 05/17/2014 |
| St3gal4, potentially involved in antithrombin sialylation, was 85% lower in neonates in comparison with adults | Control of post-translational modifications in antithrombin during murine post-natal development by miR-200a.
Teruel R, Martínez-Martínez I, Guerrero JA, González-Conejero R, de la Morena-Barrio ME, Salloum-Asfar S, Arroyo AB, Águila S, García-Barberá N, Miñano A, Vicente V, Corral J, Martínez C., Free PMC Article | 02/15/2014 |
| Expression of the sialyltransferase, ST3Gal4, impacts cardiac voltage-gated sodium channel activity, refractory period and ventricular conduction. | Expression of the sialyltransferase, ST3Gal4, impacts cardiac voltage-gated sodium channel activity, refractory period and ventricular conduction.
Ednie AR, Horton KK, Wu J, Bennett ES. | 11/2/2013 |
| Coordinated participation of both ST3Gal-VI and ST3Gal-IV in the synthesis of functional selectin ligands. | Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands.
Yang WH, Nussbaum C, Grewal PK, Marth JD, Sperandio M., Free PMC Article | 10/27/2012 |
| Data show that the sialyltransferase enzymes St6gal1 and St3gal4 are responsible for the production of sialyllactose in mouse milk. | Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization.
Fuhrer A, Sprenger N, Kurakevich E, Borsig L, Chassard C, Hennet T., Free PMC Article | 02/5/2011 |
| Sialylation by ST3Gal-IV significantly contributes to CXCR2-mediated leukocyte adhesion during inflammation in vivo. | Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
Frommhold D, Ludwig A, Bixel MG, Zarbock A, Babushkina I, Weissinger M, Cauwenberghs S, Ellies LG, Marth JD, Beck-Sickinger AG, Sixt M, Lange-Sperandio B, Zernecke A, Brandt E, Weber C, Vestweber D, Ley K, Sperandio M., Free PMC Article | 01/21/2010 |
| operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands | Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Ellies LG, Ditto D, Levy GG, Wahrenbrock M, Ginsburg D, Varki A, Le DT, Marth JD., Free PMC Article | 01/21/2010 |
| was found to play a role in regulating synthesis of selectin ligands and in vitro rolling of marrow-derived neutrophils on E- or P-selectins presented by Chinese hamster ovary cells | Sialyltransferase specificity in selectin ligand formation.
Ellies LG, Sperandio M, Underhill GH, Yousif J, Smith M, Priatel JJ, Kansas GS, Ley K, Marth JD. | 01/21/2010 |
| Regulates P-selectin ligand protein, the molecule responsible for L-selectin-mediated leukocyte interactions in inflammation. | Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation.
Sperandio M, Frommhold D, Babushkina I, Ellies LG, Olson TS, Smith ML, Fritzsching B, Pauly E, Smith DF, Nobiling R, Linderkamp O, Marth JD, Ley K. | 01/21/2010 |