| Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer. | Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.
Huang F, Zhao N, Cai P, Hou M, Yang S, Zheng B, Ma Q, Jiang J, Gai X, Mao Y, Wang L, Hu Z, Zha X, Liu F, Zhang H. | 05/13/2024 |
| m 6 A reader IGF2BP1 reduces the sensitivity of nasopharyngeal carcinoma cells to Taxol by upregulation of AKT2. | m 6 A reader IGF2BP1 reduces the sensitivity of nasopharyngeal carcinoma cells to Taxol by upregulation of AKT2.
Zhao C, Zhang F, Tian Y, Tang B, Luo J, Zhang J. | 05/13/2024 |
| Differential prognostic values of the three AKT isoforms in acute myeloid leukemia. | Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.
Corre E, Soum C, Pfeifer R, Bessière C, Dailhau S, Marbœuf C, Meggetto F, Touriol C, Récher C, Bousquet M, Pyronnet S., Free PMC Article | 04/5/2024 |
| All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines. | All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.
Tian LY, Smit DJ, Popova NV, Horn S, Velasquez LN, Huber S, Jücker M., Free PMC Article | 03/13/2024 |
| Differential activation of AKT isoforms by growth factors in human myotubes. | Differential activation of AKT isoforms by growth factors in human myotubes.
Roberts BM, Geddis AV, Matheny RW Jr., Free PMC Article | 11/13/2023 |
| Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-kappaB pathways. | Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Yin J, Hu T, Xu L, Zhang L, Zhu J, Ye Y, Pang Z. | 09/23/2023 |
| CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis. | CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis.
Wu L, Xiao H, Hong Y, Xie M, Yu Y, Jiang L., Free PMC Article | 09/12/2023 |
| Phosphatase and tensin homologue determine inflammatory status by differentially regulating the expression of Akt1 and Akt2 in macrophage alternative polarization of periodontitis. | Phosphatase and tensin homologue determine inflammatory status by differentially regulating the expression of Akt1 and Akt2 in macrophage alternative polarization of periodontitis.
Wu X, Wang Y, Chen H, Wang Y, Gu Y. | 02/14/2023 |
| Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes. | Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes.
Mäkinen S, Datta N, Rangarajan S, Nguyen YH, Olkkonen VM, Latva-Rasku A, Nuutila P, Laakso M, Koistinen HA., Free PMC Article | 01/14/2023 |
| CircPTK2 accelerates tumorigenesis of colorectal cancer by upregulating AKT2 expression via miR-506-3p. | CircPTK2 accelerates tumorigenesis of colorectal cancer by upregulating AKT2 expression via miR-506-3p.
Gong SX, Yang FS, Qiu DD. | 11/19/2022 |
| Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy. | Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, Jayagopal A, Handa JT, Zigler JS Jr, Fort PE, Sodhi A, Sinha D., Free PMC Article | 10/22/2022 |
| AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression. | AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression.
Zhang ZD, Wen B, Li DJ, Deng DX, Wu XD, Cheng YW, Liao LD, Long L, Dong G, Xu LY, Li EM. | 05/7/2022 |
| Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father. | Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father.
Dushar M, Nowaczyk J, Pyrżak B, Akopyan H, Śmigiel R, Walczak A, Rydzanicz M, Płoski R, Szczałuba K. | 03/5/2022 |
| Association between AKT2 gene polymorphism and polycystic ovary syndrome: a case-control study. | Association between AKT2 gene polymorphism and polycystic ovary syndrome: a case-control study.
Li J, Mo S, Sun Y, Huang H, Wang S. | 01/22/2022 |
| Role of AMPK and Akt in triple negative breast cancer lung colonization. | Role of AMPK and Akt in triple negative breast cancer lung colonization.
Johnson J, Chow Z, Lee E, Weiss HL, Evers BM, Rychahou P., Free PMC Article | 11/22/2021 |
| Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo. | Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.
Su B, Zhang L, Zhuang W, Zhang W, Chen X., Free PMC Article | 09/25/2021 |
| A functional SNP in miR-625-5p binding site of AKT2 3'UTR is associated with noise-induced hearing loss susceptibility in the Chinese population. | A functional SNP in miR-625-5p binding site of AKT2 3'UTR is associated with noise-induced hearing loss susceptibility in the Chinese population.
Miao L, Wang B, Zhang J, Yin L, Pu Y. | 09/18/2021 |
| Ultrasound Microbubble-Mediated microRNA-505 Regulates Cervical Cancer Cell Growth via AKT2. | Ultrasound Microbubble-Mediated microRNA-505 Regulates Cervical Cancer Cell Growth via AKT2.
Xu L, Zhang Q, Li C, Hua F, Liu X., Free PMC Article | 08/7/2021 |
| AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma. | AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.
Liu T, Zhu J, Du W, Ning W, Zhang Y, Zeng Y, Liu Z, Huang JA., Free PMC Article | 07/24/2021 |
| A novel miRNA located in the GATA4 gene regulates the expression of IGF-1R and AKT1/2 genes and controls cell proliferation. | A novel miRNA located in the GATA4 gene regulates the expression of IGF-1R and AKT1/2 genes and controls cell proliferation.
Medlej A, Mohammad Soltani B, Javad Mowla S, Hosseini S, Baharvand H. | 07/10/2021 |
| miR-664b-5p Inhibits Hepatocellular Cancer Cell Proliferation Through Targeting Oncogene AKT2. | miR-664b-5p Inhibits Hepatocellular Cancer Cell Proliferation Through Targeting Oncogene AKT2.
Li H, Guo D, Zhang Y, Yang S, Zhang R. | 07/3/2021 |
| Fusobacterium nucleatum promotes epithelial-mesenchymal transiton through regulation of the lncRNA MIR4435-2HG/miR-296-5p/Akt2/SNAI1 signaling pathway. | Fusobacterium nucleatum promotes epithelial-mesenchymal transiton through regulation of the lncRNA MIR4435-2HG/miR-296-5p/Akt2/SNAI1 signaling pathway.
Zhang S, Li C, Liu J, Geng F, Shi X, Li Q, Lu Z, Pan Y., Free PMC Article | 05/22/2021 |
| MicroRNA1493p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma. | MicroRNA‑149‑3p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma.
Shen Q, Zhu H, Lei Q, Chen L, Yang D, Sui W., Free PMC Article | 05/8/2021 |
| Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression. | Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression.
Shi Y, Mao Z, Huang Y, Sun Y, Cao Q, Yin X, Huang J, Zhang Q., Free PMC Article | 04/3/2021 |
| [Effect of glucose on Akt2 mRNA and methylation level and the association between early-pregnancy Akt2 mRNA level in peripheral blood and pre-pregnancy BMI and GDM]. | [Effect of glucose on Akt2 mRNA and methylation level and the association between early-pregnancy Akt2 mRNA level in peripheral blood and pre-pregnancy BMI and GDM].
Zhang QD, Su RN, Qin ST, Wang C, Wei YM. | 02/13/2021 |