| ERRgamma-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress. | ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress.
Jung YS, Radhakrishnan K, Hammad S, Müller S, Müller J, Noh JR, Kim J, Lee IK, Cho SJ, Kim DK, Kim YH, Lee CH, Dooley S, Choi HS., Free PMC Article | 04/3/2024 |
| Estrogen receptor-related receptor gamma uppresses hypoxia-induced angiogenesis by regulating VEGFA in endometrial cancer. | Estrogen receptor-related receptor γ uppresses hypoxia-induced angiogenesis by regulating VEGFA in endometrial cancer.
Wang XX, Hua T, Wang HB. | 11/13/2023 |
| Role of Estrogen-Related Receptor gamma and PGC-1alpha/SIRT3 Pathway in Early Brain Injury After Subarachnoid Hemorrhage. | Role of Estrogen-Related Receptor γ and PGC-1α/SIRT3 Pathway in Early Brain Injury After Subarachnoid Hemorrhage.
Guo Y, Hu Y, Huang Y, Huang L, Kanamaru H, Takemoto Y, Li H, Li D, Gu J, Zhang JH., Free PMC Article | 06/22/2023 |
| Nuclear receptor estrogen-related receptor gamma suppresses colorectal cancer aggressiveness by regulating Wnt/beta-catenin signaling. | Nuclear receptor estrogen-related receptor gamma suppresses colorectal cancer aggressiveness by regulating Wnt/β-catenin signaling.
Guo X, Yue L, Li M, Dai A, Sun J, Fang L, Zhao H, Sun Q. | 10/29/2022 |
| Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placentadagger. | Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta†.
Zou Z, Harris LK, Forbes K, Heazell AEP., Free PMC Article | 06/25/2022 |
| The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation. | The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation.
Sakamoto T, Batmanov K, Wan S, Guo Y, Lai L, Vega RB, Kelly DP., Free PMC Article | 04/30/2022 |
| Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism. | Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism.
Li W, Gong M, Park YP, Elshikha AS, Choi SC, Brown J, Kanda N, Yeh WI, Peters L, Titov AA, Teng X, Brusko TM, Morel L., Free PMC Article | 02/26/2022 |
| Estrogen-related receptor-gamma influences Helicobacter pylori infection by regulating TFF1 in gastric cancer. | Estrogen-related receptor-gamma influences Helicobacter pylori infection by regulating TFF1 in gastric cancer.
Kang MH, Eyun SI, Park YY. | 11/13/2021 |
| Expression of estrogen-related receptors in ovarian cancer and impact on survival. | Expression of estrogen-related receptors in ovarian cancer and impact on survival.
Schüler-Toprak S, Weber F, Skrzypczak M, Ortmann O, Treeck O., Free PMC Article | 08/21/2021 |
| Orphan Nuclear Receptor ERRgamma Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes. | Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes.
Kim BE, Choi B, Park WR, Kim YJ, Kim IY, Jung YS, Kim YH, Lee CH, Choi HS, Kim DK., Free PMC Article | 07/17/2021 |
| N6-methyladenosine-induced ERRgamma triggers chemoresistance of cancer cells through upregulation of ABCB1 and metabolic reprogramming. | N6-methyladenosine-induced ERRγ triggers chemoresistance of cancer cells through upregulation of ABCB1 and metabolic reprogramming.
Chen Z, Wu L, Zhou J, Lin X, Peng Y, Ge L, Chiang CM, Huang H, Wang H, He W., Free PMC Article | 05/1/2021 |
| MiR-424 may be associated with the pathogenesis of fetal growth restriction by modulating trophoblast-derived cell line proliferation and invasion. MiR-424 may play a role in mediating the protein expressions of ERRgamma and HSD17B1. | Potential role of microRNA-424 in regulating ERRγ to suppress trophoblast proliferation and invasion in fetal growth restriction.
Zou Z, He Z, Cai J, Huang L, Zhu H, Luo Y. | 06/13/2020 |
| Overexpression of human ERRgamma in mice favors hepatic VLDL-TG secretion, indicating a novel role of ERRgamma in hepatic TG metabolism. | Estrogen-related receptor γ regulates hepatic triglyceride metabolism through phospholipase A2 G12B.
Chen L, Wu M, Zhang S, Tan W, Guan M, Feng L, Chen C, Tao J, Chen L, Qu L. | 05/30/2020 |
| ESRRG promoter hypermethylation contributed to laryngeal squamous cell carcinoma-related risks, primarily tumor progression and survival prognosis, in patients. ESRRG promoter methylation could, therefore, be a diagnostic and prognostic biomarker in laryngeal squamous cell carcinoma. | ESRRG promoter hypermethylation as a diagnostic and prognostic biomarker in laryngeal squamous cell carcinoma.
Shen Z, Hu Y, Zhou C, Yuan J, Xu J, Hao W, Deng H, Ye D., Free PMC Article | 01/11/2020 |
| A novel endogenous steroid Estradienolone acts as an inverse agonist of ERR-alpha and ERR-gamma by directly interacting with these receptors, and inhibiting their transcriptional activity. | Isolation and functional characterization of a novel endogenous inverse agonist of estrogen related receptors (ERRs) from human pregnancy urine.
Ghanbari F, Hebert-Losier A, Barry J, Poirier D, Giguere V, Mader S, Philip A. | 11/23/2019 |
| Aberrant ERRgamma expression may contribute to the pathogenesis of FGR by regulating the transcriptional activity of HSD17B1. | Estrogen-related receptor γ regulates expression of 17β-hydroxysteroid dehydrogenase type 1 in fetal growth restriction.
Zhu H, Huang L, He Z, Zou Z, Luo Y. | 08/31/2019 |
| This study suggests that the ESRRG rs1890552 A > G polymorphism may modulate interindividual differences in atrial stiffness, with a reduction in fasting glucose in response to dietary advice in subjects with IFG after a 3.5-year follow-up. | Influence of estrogen-related receptor γ (ESRRG) rs1890552 A > G polymorphism on changes in fasting glucose and arterial stiffness.
Kim M, Yoo HJ, Kim M, Seo H, Chae JS, Lee SH, Lee JH., Free PMC Article | 04/20/2019 |
| EZH2 as a relevant coregulator for estrogen-related receptors alpha, beta and gamma in breast carcinoma. | Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma.
Kumari K, Adhya AK, Rath AK, Reddy PB, Mishra SK., Free PMC Article | 02/2/2019 |
| ESRRG functions as a negative regulator of the Wnt signaling pathway in gastric cancer. | Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.
Kang MH, Choi H, Oshima M, Cheong JH, Kim S, Lee JH, Park YS, Choi HS, Kweon MN, Pack CG, Lee JS, Mills GB, Myung SJ, Park YY., Free PMC Article | 02/2/2019 |
| ERRgamma may exert oncogenic activity mainly associated with aggressiveness of EC by activating S100A4 transcription. | Estrogen‑related receptor γ promotes the migration and metastasis of endometrial cancer cells by targeting S100A4.
Hua T, Wang X, Chi S, Liu Y, Feng D, Zhao Y, Wang H. | 10/13/2018 |
| Loss of ERRgamma in renal epithelial cells Results in Kidney Disease with Cysts. | Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease.
Zhao J, Lupino K, Wilkins BJ, Qiu C, Liu J, Omura Y, Allred AL, McDonald C, Susztak K, Barish GD, Pei L., Free PMC Article | 09/1/2018 |
| our present results show an intriguing association between the ESRRG rs1890552 GG genotype and an increased risk of impaired fasting glucose or type 2 diabetes mellitus as well as increased oxidative stress. | Estrogen-related receptor γ gene (ESRRG) rs1890552 A>G polymorphism in a Korean population: Association with urinary prostaglandin F2α concentration and impaired fasting glucose or newly diagnosed type 2 diabetes.
Kim M, Kim M, Yoo HJ, Yun R, Lee SH, Lee JH. | 06/30/2018 |
| It was also associated with beta-cell function (P=1.99 x 10(-3)) and fasting glucose level (P<0.05) in the meta-analyses of glucose and insulin-related traits consortium (MAGIC) data set.Cnoclusions:In summary, we identified epigenomic characteristics for obesity genes and suggested ESRRG as a novel obesity-susceptibility gene | Epigenomic elements analyses for promoters identify ESRRG as a new susceptibility gene for obesity-related traits.
Dong SS, Guo Y, Zhu DL, Chen XF, Wu XM, Shen H, Chen XD, Tan LJ, Tian Q, Deng HW, Yang TL., Free PMC Article | 01/20/2018 |
| this study elucidates a molecular mechanism linking CB1R signaling, ERRgamma expression and fibrinogen gene transcription. | Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression.
Zhang Y, Kim DK, Lu Y, Jung YS, Lee JM, Kim YH, Lee YS, Kim J, Dewidar B, Jeong WI, Lee IK, Cho SJ, Dooley S, Lee CH, Li X, Choi HS., Free PMC Article | 10/7/2017 |
| Disruption of the orphan receptor ESRRG and disruption of KIAA0825 identified in a subject with hearing loss and mild developmental delay. Given the translocation breakpoints and supporting literature, disruption of ESRRG is the most likely cause for the disorder. | Estrogen-related receptor gamma implicated in a phenotype including hearing loss and mild developmental delay.
Schilit SL, Currall BB, Yao R, Hanscom C, Collins RL, Pillalamarri V, Lee DY, Kammin T, Zepeda-Mendoza CJ, Mononen T, Nolan LS, Gusella JF, Talkowski ME, Shen J, Morton CC., Free PMC Article | 07/8/2017 |