| Reduction of ETV1 is Identified as a Prominent Feature of Age-Related Cataract. | Reduction of ETV1 is Identified as a Prominent Feature of Age-Related Cataract.
Qiu X, Zhang S, Zhang Y, Cai L, Li D, Lu Y. | 04/24/2024 |
| Transcription factor ETV1-induced lncRNA MAFG-AS1 promotes migration, invasion, and epithelial-mesenchymal transition of pancreatic cancer cells by recruiting IGF2BP2 to stabilize ETV1 expression. | Transcription factor ETV1-induced lncRNA MAFG-AS1 promotes migration, invasion, and epithelial-mesenchymal transition of pancreatic cancer cells by recruiting IGF2BP2 to stabilize ETV1 expression.
Weng H, Feng W, Li F, Huang D, Lin L, Wang Z. | 08/3/2023 |
| HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET. | HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET.
Zhang T, Wang Y, Xie M, Ji X, Luo X, Chen X, Zhang B, Liu D, Feng Y, Sun M, Huang W, Xia L., Free PMC Article | 10/1/2022 |
| ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer. | ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer.
Shen X, Zhou C, Feng H, Li J, Xia T, Cheng X, Zhao R, Zou D., Free PMC Article | 08/6/2022 |
| Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas. | Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas.
Hoff AM, Kraggerud SM, Alagaratnam S, Berg KCG, Johannessen B, Høland M, Nilsen G, Lingjærde OC, Andrews PW, Lothe RA, Skotheim RI., Free PMC Article | 08/28/2021 |
| Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer. | Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer.
Oh S, Song H, Freeman WM, Shin S, Janknecht R., Free PMC Article | 08/7/2021 |
| Low ETV1 mRNA expression is associated with recurrence in gastrointestinal stromal tumors. | Low ETV1 mRNA expression is associated with recurrence in gastrointestinal stromal tumors.
Sakamaki K, Funasaka K, Miyahara R, Furukawa K, Yamamura T, Ohno E, Nakamura M, Kawashima H, Hirooka Y, Fujishiro M, Goto H., Free PMC Article | 03/28/2021 |
| Identification of regulatory mRNA and microRNA for differentiation into cementoblasts and periodontal ligament cells. | Identification of regulatory mRNA and microRNA for differentiation into cementoblasts and periodontal ligament cells.
Iwata T, Mizuno N, Nagahara T, Kaneda-Ikeda E, Kajiya M, Kitagawa M, Takeda K, Yoshioka M, Yagi R, Takata T, Kurihara H. | 02/6/2021 |
| A novel PTPRZ1-ETV1 fusion in gliomas. | A novel PTPRZ1-ETV1 fusion in gliomas.
Matjašič A, Zupan A, Boštjančič E, Pižem J, Popović M, Kolenc D., Free PMC Article | 01/2/2021 |
| Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis. | Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis.
Li H, Shen S, Ruan X, Liu X, Zheng J, Liu Y, Yang C, Wang D, Liu L, Ma J, Ma T, Wang P, Cai H, Li Z, Zhao L, Xue Y., Free PMC Article | 09/12/2020 |
| Dualism of FGF and TGF-beta Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. | Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant.
Bordignon P, Bottoni G, Xu X, Popescu AS, Truan Z, Guenova E, Kofler L, Jafari P, Ostano P, Röcken M, Neel V, Dotto GP., Free PMC Article | 08/29/2020 |
| Findings cast light on genes and networks regulated by ETV1 in prostate cancer cells, and open new fronts for studying the role of ETV1 and its target genes in tumorigenesis. | Genome-wide analysis of ETV1 targets: Insights into the role of ETV1 in tumor progression.
Eid W, Abdel-Rehim W. | 07/25/2020 |
| ERG overexpression was observed in 85 of 151 (56%) cases, followed by SPINK1 in 61 of 151 (40%), ETV1 in 9 of 149 (6%), and ETV4 in 4 of 141 (3%). There were 25 of 151 (17%) cases showing both ERG and SPINK1 overexpression within different regions of either the same tumor focus or different foci. | Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1, ETV1, and ETV4 on whole-mount radical prostatectomy tissue.
Lu Z, Williamson SR, Carskadon S, Arachchige PD, Dhamdhere G, Schultz DS, Stricker H, Peabody JO, Jeong W, Chitale DA, Bismar TA, Rogers CG, Menon M, Gupta NS, Palanisamy N. | 04/18/2020 |
| Strong ETV1 protein expression has a negative impact on prostate cancer outcome | Strong cytoplasmic ETV1 expression has a negative impact on prostate cancer outcome.
Segalés L, Juanpere N, Lorenzo M, Albero-González R, Fumadó L, Cecchini L, Bellmunt J, Lloreta-Trull J, Hernández-Llodrà S. | 11/16/2019 |
| A cardiomyocyte-autonomous, ETV1-dependent pathway that is responsible for specification of rapid conduction zones in the heart was identified. | ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes.
Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS., Free PMC Article | 11/16/2019 |
| Our data indicate that miR-17-5p acts as a tumour suppressor in Triple-negative breast cancer (TNBC)by targeting ETV1, and a low-abundance of miR-17-5p may be involved in the pathogenesis of TNBC. These findings indicate that miR-17-5p may be a therapeutic target for TNBC | miR-17-5p suppresses cell proliferation and invasion by targeting ETV1 in triple-negative breast cancer.
Li J, Lai Y, Ma J, Liu Y, Bi J, Zhang L, Chen L, Yao C, Lv W, Chang G, Wang S, Ouyang M, Wang W., Free PMC Article | 07/14/2018 |
| four oncogenic ETS (ERG, ETV1, ETV4, and ETV5), and no other ETS, interact with the Ewing's sarcoma breakpoint protein, EWS. | An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.
Kedage V, Selvaraj N, Nicholas TR, Budka JA, Plotnik JP, Jerde TJ, Hollenhorst PC., Free PMC Article | 11/25/2017 |
| Our results indicate that assessing AP1 and PEA3 transcription factor status might be a good indicator of OAC status. However, we could not detect any associations with disease stage or patient treatment regime. This suggests that the PEA3-AP1 regulatory module more likely contributes more generally to the cancer phenotype. In keeping with this observation, depletion of ETV1 and/or ETV4 causes an OAC cell growth defect | Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.
Britton E, Rogerson C, Mehta S, Li Y, Li X, OCCAMS consortium, Fitzgerald RC, Ang YS, Sharrocks AD., Free PMC Article | 09/23/2017 |
| Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETV1, ETV4 and ETV5. | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Currie SL, Lau DKW, Doane JJ, Whitby FG, Okon M, McIntosh LP, Graves BJ., Free PMC Article | 07/22/2017 |
| the prostate cancer-related oncogenic E26 transformation-specific (ETS) transcription factors, ETV1, ETV4, and ETV5, were required for TAZ gene transcription in PC3 prostate cancer cells | ETS (E26 transformation-specific) up-regulation of the transcriptional co-activator TAZ promotes cell migration and metastasis in prostate cancer.
Liu CY, Yu T, Huang Y, Cui L, Hong W., Free PMC Article | 06/10/2017 |
| C646 treatment attenuated ETV1 protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 may serve as novel antineoplastic targets and that use of the selective HAT inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors. | An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells.
Gu ML, Wang YM, Zhou XX, Yao HP, Zheng S, Xiang Z, Ji F. | 03/18/2017 |
| these data reveal a JMJD2A/ETV1/YAP1 axis that promotes prostate cancer initiation and that may be a suitable target for therapeutic inhibition. | Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.
Kim TD, Jin F, Shin S, Oh S, Lightfoot SA, Grande JP, Johnson AJ, van Deursen JM, Wren JD, Janknecht R., Free PMC Article | 07/16/2016 |
| conclude that ETV1 is specifically expressed in the majority of gastrointestinal stromal tumors, even in some KIT-negative cases | ETV1 mRNA is specifically expressed in gastrointestinal stromal tumors.
Jang BG, Lee HE, Kim WH. | 02/6/2016 |
| ETV1 and COP1 are a pair of independent predictors of prognosis for triple-negative breast cancer. | COP1, the negative regulator of ETV1, influences prognosis in triple-negative breast cancer.
Ouyang M, Wang H, Ma J, Lü W, Li J, Yao C, Chang G, Bi J, Wang S, Wang W., Free PMC Article | 01/23/2016 |
| ETV1 overexpression is associated with prostate cancer aggressiveness. | Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts.
Mesquita D, Barros-Silva JD, Santos J, Skotheim RI, Lothe RA, Paulo P, Teixeira MR., Free PMC Article | 01/23/2016 |