| BCL6B-dependent suppression of ETV2 hampers endothelial cell differentiation. | BCL6B-dependent suppression of ETV2 hampers endothelial cell differentiation.
Li Z, Wu W, Li Q, Heng X, Zhang W, Zhu Y, Chen L, Chen Z, Shen M, Ma N, Xiao Q, Yan Y., Free PMC Article | 09/6/2024 |
| SOX17/ETV2 improves the direct reprogramming of adult fibroblasts to endothelial cells. | SOX17/ETV2 improves the direct reprogramming of adult fibroblasts to endothelial cells.
Grath A, Dai G., Free PMC Article | 03/29/2024 |
| ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment. | ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment.
Steimle JD, Kim C, Rowton M, Nadadur RD, Wang Z, Stocker M, Hoffmann AD, Hanson E, Kweon J, Sinha T, Choi K, Black BL, Cunningham JM, Moskowitz IP, Ikegami K., Free PMC Article | 10/13/2023 |
| ETV2/ER71, the key factor leading the paths to vascular regeneration and angiogenic reprogramming. | ETV2/ER71, the key factor leading the paths to vascular regeneration and angiogenic reprogramming.
Kim TM, Lee RH, Kim MS, Lewis CA, Park C., Free PMC Article | 03/20/2023 |
| A 3-Gene Random Forest Model to Diagnose Non-obstructive Azoospermia Based on Transcription Factor-Related Henes. | A 3-Gene Random Forest Model to Diagnose Non-obstructive Azoospermia Based on Transcription Factor-Related Henes.
Zhou R, Liang J, Chen Q, Tian H, Yang C, Liu C. | 01/14/2023 |
| ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways. | ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways.
Li J, Du H, Ji X, Chen Y, Li Y, Heng BC, Xu J., Free PMC Article | 10/15/2022 |
| ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells. | ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells.
Shrestha S, Lamattina A, Pacheco-Rodriguez G, Ng J, Liu X, Sonawane A, Imani J, Qiu W, Kosmas K, Louis P, Hentschel A, Steagall WK, Onishi R, Christou H, Henske EP, Glass K, Perrella MA, Moss J, Tantisira K, El-Chemaly S., Free PMC Article | 05/7/2022 |
| Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA. | Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA.
Wang K, Lin RZ, Hong X, Ng AH, Lee CN, Neumeyer J, Wang G, Wang X, Ma M, Pu WT, Church GM, Melero-Martin JM., Free PMC Article | 04/23/2022 |
| Morphological characterization of Etv2 vascular explants using fractal analysis and atomic force microscopy. | Morphological characterization of Etv2 vascular explants using fractal analysis and atomic force microscopy.
Adelson RP, Palikuqi B, Weiss Z, Checco A, Schreiner R, Rafii S, Rabbany SY., Free PMC Article | 03/5/2022 |
| Upregulation of ETV2 Expression Promotes Endothelial Differentiation of Human Dental Pulp Stem Cells. | Upregulation of ETV2 Expression Promotes Endothelial Differentiation of Human Dental Pulp Stem Cells.
Li J, Zhu Y, Li N, Wu T, Zheng X, Heng BC, Zou D, Xu J., Free PMC Article | 12/25/2021 |
| Biallelic variants in ETV2 in a family with congenital heart defects, vertebral abnormalities and preaxial polydactyly. | Biallelic variants in ETV2 in a family with congenital heart defects, vertebral abnormalities and preaxial polydactyly.
Basel-Salmon L, Ruhrman-Shahar N, Barel O, Hagari O, Marek-Yagel D, Azulai N, Bazak L, Svirsky R, Reznik-Wolf H, Lidzbarsky GA, Shohat M. | 06/26/2021 |
| FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK. | FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK.
Chen PC, Hsueh YW, Lee YH, Tsai HW, Tsai KJ, Chiang PM., Free PMC Article | 04/3/2021 |
| ETV2/ER71 Transcription Factor as a Therapeutic Vehicle for Cardiovascular Disease. | ETV2/ER71 Transcription Factor as a Therapeutic Vehicle for Cardiovascular Disease.
Lee DH, Kim TM, Kim JK, Park C., Free PMC Article | 08/22/2020 |
| These findings provide insight into the novel molecular mechanisms of ETV2 function in regulating cardiovascular lineage development from mouse embryonic stem cells. | ETV2/ER71 regulates the generation of FLK1(+) cells from mouse embryonic stem cells through miR-126-MAPK signaling.
Kim JY, Lee DH, Kim JK, Choi HS, Dwivedi B, Rupji M, Kowalski J, Green SJ, Song H, Park WJ, Chang JY, Kim TM, Park C., Free PMC Article | 07/25/2020 |
| among the many factors wired within this complex regulatory network, ETV2, SCL and RUNX1 are the central components. All three factors are absolutely required for blood cell generation, each one controlling a precise step of specification from the mesoderm germ layer to fully functional blood progenitors | Transcriptional control of blood cell emergence.
Menegatti S, de Kruijf M, Garcia-Alegria E, Lacaud G, Kouskoff V., Free PMC Article | 06/20/2020 |
| ETS transcription factor Etv2, a critical factor for haematopoietic and vascular development, is also required for haematopoietic regeneration. Etv2, which is silent in homeostatic HSCs, was transiently activated in regenerating HSPCs and was required for the HSC expansion and regeneration following bone marrow transplantation or haematopoietic injury. | ETS transcription factor ETV2/ER71/Etsrp in haematopoietic regeneration.
Choi K. | 03/9/2019 |
| REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. | ETS transcription factor ETV2/ER71/Etsrp in hematopoietic and vascular development, injury, and regeneration.
Zhao H, Xu C, Lee TJ, Liu F, Choi K. | 02/17/2018 |
| Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. | Significant improvement of direct reprogramming efficacy of fibroblasts into progenitor endothelial cells by ETV2 and hypoxia.
Van Pham P, Vu NB, Nguyen HT, Huynh OT, Truong MT., Free PMC Article | 11/18/2017 |
| ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. | Direct Reprogramming of Human Dermal Fibroblasts Into Endothelial Cells Using ER71/ETV2.
Lee S, Park C, Han JW, Kim JY, Cho K, Kim EJ, Kim S, Lee SJ, Oh SY, Tanaka Y, Park IH, An HJ, Shin CM, Sharma S, Yoon YS., Free PMC Article | 05/13/2017 |
| ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. | ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.
Morita R, Suzuki M, Kasahara H, Shimizu N, Shichita T, Sekiya T, Kimura A, Sasaki K, Yasukawa H, Yoshimura A., Free PMC Article | 04/25/2015 |
| identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp | Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation.
Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S., Free PMC Article | 01/21/2010 |